T-box 3 (Tbx3, T-box family of transcription factors)

TBX3 belongs to the T-box family of transcription factors, which are involved in regulation of developmental processes. TBX3 acts as a transcriptional repressor regulating anterior/posterior axis of the forelimb. Mutations in TBX3 are associated with ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. TBX3 has 3 splice isoforms.|Preparation|Goat antibodies were raised against purified, E. coli-derived, recombinant human TBX3 (rhTBX3; aa 321-487; Accession # NM_016569). Polyclonal antibody was affinity-purified on a column derivatized with rhTBX3 and further purified by isolating the IgG fraction.||Applications: |Suitable for use in ELISA, Western Blotting. Other applications not tested.||Recommended Dilution:|Western Blotting: 1ug/ml|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.