Leflunomide-d4 [1189987-23-2]
Katalog-Nummer HY-B0083S-500ug
Size : 500ug
Marke : MedChemExpress
Leflunomide-d4 (HWA486-d4) is the deuterium labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent[1][2].
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
Leflunomide-d4 Chemische Struktur
CAS. Nr. : 1189987-23-2
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Leflunomide-d4:
- Leflunomide In-stock
Beschreibung |
Leflunomide-d4 (HWA486-d4) is the deuterium labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent[1][2]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
Molekulargewicht |
274.23 |
Formel |
C12H5D4F3N2O2 |
CAS. Nr. |
1189987-23-2 |
Unlabeled CAS |
75706-12-6 |
SMILES |
C(NC1=C(C(=C(C(F)(F)F)C(=C1[2H])[2H])[2H])[2H])(=O)C2=C(C)ON=C2 |
Versand | Room temperature in continental US; may vary elsewhere. |
Speicherung |
Please store the product under the recommended conditions in the Certificate of Analysis. |
Reinheit & Dokumentation | |
Verweise |
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Leflunomide-d4 Related Classifications
- Cancer
- Cancer Targeted Therapy Cancer Metabolism and Metastasis
- Metabolic Enzyme/Protease
- Dihydroorotate Dehydrogenase
Molaritätsrechner
Verdünnungsrechner
Die Formel zur Berechnung von Molaritäten
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Leflunomide-d41189987-23-2Dihydroorotate DehydrogenaseDHODHInhibitorinhibitorinhibit