General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.6U/mL |
| Detection Limit: | 1.56-100U/mL |
| Short Description: | This AANAT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | AANAT |
| Gene ID: | 15 |
| Uniprot ID: | SNAT_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Description
| Tissue Specificity | Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. |
| Post Translational Modifications | cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. |
| Function | Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. |
| Protein Name | Serotonin N-AcetyltransferaseSerotonin AcetylaseAralkylamine N-AcetyltransferaseAa-Nat |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Serotonin N-Acetyltransferase ELISA kitSerotonin Acetylase ELISA kitAralkylamine N-Acetyltransferase ELISA kitAa-Nat ELISA kitAANAT ELISA kitSNAT ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance