HSP90AA1 Antibody
Katalog-Nummer OAED00217
Size : 50ug
Marke : Aviva Systems Biology
Contact local distributor :
Telefonnummer : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for anti-HSP90AA1 (OAED00217) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Bovine, Beluga, Dog, Fish, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Sheep, Xenopus |
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| Clonality | Polyclonal |
| Host | Rabbit |
| Application | FC |
| Reconstitution and Storage | Long Term Storage : +4C |
| Immunogen | Synthetic peptide corresponding to a portion of mouse Hsp86. |
| Specificity | Recognizes human, mouse, rat, bovine, beluga, dog, fish, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus Hsp90 alpha. Detects a band of ~90kDa by Western blot. |
| Formulation | Liquid. In PBS, pH 7.2, containing 0.09% sodium azide. |
| Purity | Protein A-affinity purified. |
| Application Info | Flow Cytometry (1:100) Optimal conditions must be determined individually for each application. |
| Gene Symbol | HSP90AA1 |
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| Gene Full Name | Heat shock protein HSP 90-alpha |
| Alias Symbols | EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p |
| NCBI Gene Id | 3320 |
| Protein Name | Heat shock protein HSP 90-alpha |
| Description of Target | The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents. |
| Uniprot ID | P07900 |
| Protein Accession # | NP_001017963.2; NP_005339.3 |
| Nucleotide Accession # | NM_001017963.2; NM_005348.3 |
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What is the species homology for "HSP90AA1 Antibody (OAED00217)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Bovine, Beluga, Dog, Fish, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Sheep, Xenopus".
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How long will it take to receive "HSP90AA1 Antibody (OAED00217)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "HSP90AA1 Antibody (OAED00217)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "HSP90AA1 Antibody (OAED00217)"?
This target may also be called "EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p" in publications.
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What is the shipping cost for "HSP90AA1 Antibody (OAED00217)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "HSP90AA1 Antibody (OAED00217)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "HSP90AA1 Antibody (OAED00217)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "HSP90AA1 Antibody (OAED00217)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "HSP90AA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "HSP90AA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "HSP90AA1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "HSP90AA1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "HSP90AA1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "HSP90AA1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.