Gilteritinib [1254053-43-4]
Katalog-Nummer HY-12432-5mg
Size : 5mg
Marke : MedChemExpress
Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.
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Gilteritinib Chemische Struktur
CAS. Nr. : 1254053-43-4
This product is a controlled substance and not for sale in your territory.
Based on 28 publication(s) in Google Scholar
Other Forms of Gilteritinib:
- Gilteritinib hemifumarate In-stock
- Gilteritinib-d8 In-stock
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Gilteritinib purchased from MedChemExpress. Usage Cited in: Cancer Cell Int. 2020 Jun 17;20:250. [Abstract]
- MV4-11 and MOLM13 cells are treated with Gilteritinib (2.5 nM) and/or ATO (0.5 µM) for 48 h and protein levels of P-FLT3 and FLT3 are determined by Western blot. Gilteritinib exhibits a strong inhibition on the phosphorylated FLT3 even at a low concentration of 2.5 nM, but had little effect on total FLT3 and USP10.
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Gilteritinib purchased from MedChemExpress. Usage Cited in: Cancer Cell Int. 2020 Jun 17;20:250. [Abstract]
- Proliferation assay demonstrates that FLT3-ITD mutant cells (MV4-11 and MOLM13) are more sensitive to Gilteritinib compared with FLT3-WT cells (THP1 and HL60).