FADD Polyclonal Antibody, HRP Conjugated
Katalog-Nummer bs-0511R-HRP
Size : 100ul
FADD Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Overview | |
Catalog # | bs-0511R-HRP |
Product Name | FADD Polyclonal Antibody, HRP Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Reactivity | Human, Mouse, Rat, Pig, Monkey |
Specifications | |
Conjugation | HRP |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from mouse FADD |
Immunogen Range | 1-80/205 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 14082 |
Swiss Prot | Q61160 |
Subcellular location | Cytoplasm, Cell membrane |
Synonyms | Mort1/FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Protein FADD; Fadd; Mort1 |
Background | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |