Moravek

Solutions offered by Moravek include
 
  • Custom GMP radiolabeling of [14C] APIs – suitable for use in clinical trials
  • Method transfer, development, validation and system suitability under GLP or GMP
  • GLP custom synthesis of labeled and non-labeled compounds
  • Custom synthesis of [14C], [3H], stable labeled and non-labeled compounds – non-GMP
  • Catalog of labeled compounds – 2,000 exceptionally high quality catalog items for standard research
  • Analytical services – NMR of various nuclides, MS, GC/MS, LC/MS, HPLC, UPLC, Karl Fischer and more
  • Stability studies – carried out with NIST traceable temperature tracking and qualified HPLC systems
  • Purification – by various methods including HPLC, flash chromatography and lobar
  • Comprehensive logistics services – storing, dispensing, shipping, chain of custody and temperature tracking
 
Website : www.moravek.com
 
Radioisotopes

Radioisotopes

All radioisotopes are unstable isotopes that emit radiation as a result of the nuclear disintegration they undergo. The radiation emitted is of three types: Alpha, Beta and Gamma. These three types of radiation are distinguished by their penetrating power. Indeed, alpha radiation can be stopped easily by a few centimeters of air or a sheet of paper, beta radiation can be stopped by aluminum foil and gamma radiation are the most penetrating of the 3 and are more difficult to stop .

Radioisotopes are widely used for diagnostic or research purposes. Radioisotopes present naturally or introduced into the body emit gamma rays and, after detection and treatment of the results, provide information on the anatomy of the person and on the functioning of specific organs. When used in this way the radioisotopes are called tracers.

Radiation therapy also uses radioisotopes in the treatment of certain diseases such as cancer. Powerful sources of gamma rays are also used to sterilize medical equipment.

One of the applications of radioisotopes in biology is the study of DNA with the use of Phosphorus-32 (P-32). The stable phosphorus is replaced by P-32 and the radioactivity is used to analyze molecules and their fate.