Polyclonal antibody production
Use of rabbits to produce polyclonal antibodies allow to obtain important amounts of antiserum containing a high titer of antibodies with a strong affinity to the antigen.
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Use of Goats give large volumes of antibody.
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Use of Sheeps give large volumes of antibody.
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Use of Guinea Pig give less antibody volumes however these animals are phylogenetically far from mouse in comparison with rat and then can be used to produce anti-mouse antibodies.
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Use of Chinese Hamster give few antibody volumes however they can be used to produce anti-mouse antibodies.
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Use of Donkeys give very large volumes of antibody.
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Use of rats give less antibody volumes however they allow production of IgE or strictly specific antibodies against mouse proteins.
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Use of mice give few antibody volumes however they allow a cheaper production with few antigen consuming.
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This technique allows to make the mouse express in vivo the gene coding for the antigen of interest.
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