Umifenovir-d6 (hydrochloride) [2928218-29-3]
Cat# HY-14904AS-500ug
Size : 500ug
Brand : MedChemExpress
Umifenovir-d6 (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3].
For research use only. We do not sell to patients.
Umifenovir-d6 hydrochloride Chemical Structure
CAS No. : 2928218-29-3
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Umifenovir-d6 hydrochloride:
- Umifenovir hydrochloride In-stock
Description |
Umifenovir-d6 (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Molecular Weight |
519.91 |
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Formula |
C22H20D6BrClN2O3S |
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CAS No. |
2928218-29-3 |
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Unlabeled CAS |
131707-23-8 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C(C1=C(CSC2=CC=CC=C2)N(C)C3=C1C(CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=C(O)C(Br)=C3)OCC.14Cl |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvent & Solubility |
In Vitro:
DMSO : 25 mg/mL (48.09 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Purity & Documentation |
Purity: 98.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 1.9234 mL | 9.6170 mL | 19.2341 mL | 48.0852 mL |
5 mM | 0.3847 mL | 1.9234 mL | 3.8468 mL | 9.6170 mL | |
10 mM | 0.1923 mL | 0.9617 mL | 1.9234 mL | 4.8085 mL | |
15 mM | 0.1282 mL | 0.6411 mL | 1.2823 mL | 3.2057 mL | |
20 mM | 0.0962 mL | 0.4809 mL | 0.9617 mL | 2.4043 mL | |
25 mM | 0.0769 mL | 0.3847 mL | 0.7694 mL | 1.9234 mL | |
30 mM | 0.0641 mL | 0.3206 mL | 0.6411 mL | 1.6028 mL | |
40 mM | 0.0481 mL | 0.2404 mL | 0.4809 mL | 1.2021 mL |
Umifenovir-d6 hydrochloride Related Classifications
- Infection
- Others Anti-infection
- Isotope-Labeled Compounds Influenza Virus SARS-CoV
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Umifenovir-d62928218-29-3Isotope-Labeled CompoundsInfluenza VirusSARS-CoVSARS coronavirusInhibitorinhibitorinhibit