View product citations for antibody PAB15135 on CiteAb
  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of TMED10.PAB,polyclonal Ab,polyclonal antibody

    Immunogen

    A synthetic peptide corresponding to residues within 50-150 at internal region of human TMED10.

    Host

    Rabbit

    Reactivity

    Bovine, Human, Mouse, Primates, Rabbit, Rat, Xenopus

    Specificity

    This antibody is useful for Western blot analysis where a band is seen at ~21 KDa.

    Form

    Liquid

    Conjugation

    DyLight 650

    Purification

    Immunogen affinity purification

    Recommend Usage

    Immunohistochemistry
    Western Blot
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50 mM sodium borate (0.05% sodium azide).

    Storage Instruction

    Store at 4°C in the dark.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

    Immunohistochemistry

  • Gene Info — TMED10

    Entrez GeneID

    10972

    Protein Accession#

    P49755

    Gene Name

    TMED10

    Gene Alias

    P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I

    Gene Description

    transmembrane emp24-like trafficking protein 10 (yeast)

    Omim ID

    605406

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq

    Other Designations

    21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10

  • Interactomes
  • Diseases