Staurosporine[62996-74-1]
Cat# 00025
Size : 100UG
Brand : Biotium
Contact local distributor :
Phone : +1 850 650 7790
Protocols
SDS
Supporting Documents
Product Description
Staurosporine inhibits a wide variety of protein kinases by competing for the ATP binding site. It is a potent and cell-permeable competitive inhibitor for protein kinase C (IC50 = 0.7 nM), protein kinase A (IC50 = 7 nM), and protein kinase G (IC50 = 8.5 nM) (1,2). Staurosporine induces apoptosis in human neuroblastoma cells and chick embryonic neurons (3,4).
- Cell-permeable inhibitor of protein kinases
- Competitive inhibition at the ATP binding site
- Soluble in DMSO or ethanol
- [62996-74-1]
References
1. Biochem Biophys Res Commun. 158, 105 (1989), DOI: 10.1016/S0006-291X(89)80183-4
2. Biochem Biophys Res Commun. 135, 397 (1986), DOI: 10.1016/0006-291X(86)90008-2
3. Neuropharmacology 36, 811 (1997), DOI: s0028-3908(97)00030-0
4. J. Neurochem. 66, 1418 (1996), DOI: 10.1046/j.1471-4159.1996.66041418.x
Powered by Bioz See more details on Bioz
You might also be interested by the following products:
Cat#
Description
Cond.
Price Bef. VAT