Our PCM1/JAK2 fusion probe is designed to detect fusions between PCM1 and JAK2. The probe comes labeled in orange and green, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
Gene Summary
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: PCM1
Gene Name: Pericentriolar Material 1
Chromosome: CHR8: 17780365-17887457
Locus: 8p22