OptoDArG [2230617-93-1]
Cat# AOB31427-1
Size : 1mg
Brand : AOBIOUS
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Data sheet
Molecular Formula | C43H52N4O5 |
Molecular Weight | 704.39 |
CAS Numbers | 2230617-93-1 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | OptoDArG; Opto-DArG; Opto DArG |
IUPAC/Chemical Name | 3-hydroxypropane-1,2-diyl bis(4-(4-((E)-(4-butylphenyl)diazenyl)phenyl)butanoate) |
InChl Key | ZBBHLPDZJFKXFD-NFAUJPPVSA-N |
InChl Code | InChI=1S/C43H52N4O5/c1-3-5-9-33-15-23-37(24-16-33)44-46-39-27-19-35(20-28-39)11-7-13-42(49)51-32-41(31-48)52-43(50)14-8-12-36-21-29-40(30-22-36)47-45-38-25-17-34(18-26-38)10-6-4-2/h15-30,41,48H,3-14,31-32H2,1-2H3/b46-44+,47-45+ |
SMILES Code | CCCCC1=CC=C(/N=N/C2=CC=C(CCCC(OCC(CO)OC(CCCC3=CC=C(/N=N/C4=CC=C(CCCC)C=C4)C=C3)=O)=O)C=C2)C=C1 |
References | Lichtenegger M, Tiapko O, Svobodova B, Stockner T, Glasnov TN, Schreibmayer W, Platzer D, de la Cruz GG, Krenn S, Schober R, Shrestha N, Schindl R, Romanin C, Groschner K. An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel. Nat Chem Biol. 2018 Apr;14(4):396-404. doi: 10.1038/s41589-018-0015-6. Epub 2018 Mar 19. PubMed PMID: 29556099; PubMed Central PMCID: PMC5903546. |
More info
Novel diacylglycerol (DAG) photoswitch, enabling efficient control of TRPC3 by light