Application
| IHC-P |
|---|---|
| Primary Accession | Q15761 |
| Reactivity | Human, Mouse, Hamster, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51kDa |
| Dilution | IHC-P (3-5 µg/ml) |
| Gene ID | 4889 |
|---|---|
| Other Names | Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor, NPY5R, NPYR5 |
| Target/Specificity | Human NPY5R. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | NPY5R Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPY5R |
|---|---|
| Synonyms | NPYR5 |
| Function | Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Brain; hypothalamus. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
References
Hu Y.,et al.J. Biol. Chem. 271:26315-26319(1996).
Gerald C.,et al.Nature 382:168-171(1996).
Herzog H.,et al.Genomics 41:315-319(1997).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).