NGFR Antibody

Cat# OACA10456-50UG

Size : 50ug

Brand : Aviva Systems Biology

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NGFR Antibody (OACA10456)

Datasheets/ManualsPrintable datasheet for NGFR Antibody (OACA10456)
Product Info
Predicted Species ReactivityHuman|Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationELISA|IHC|WB
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Tumor necrosis factor receptor superfamily member 16 protein (277-391AA)
PurificationProtein G Purified
Preservative0.03% Proclin 300
Formulation50% Glycerol, 0.01M PBS, pH 7.4
Purity>95%
Gene SymbolNGFR
Gene Full Namenerve growth factor receptor
Alias SymbolsCD271, Gp80-LNGFR, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, TNFRSF16, tumor necrosis factor receptor superfamily member 16.
NCBI Gene Id4804
Protein NameTumor necrosis factor receptor superfamily member 16
Description of TargetPlays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Uniprot IDP08138
Protein Accession #NP_002498
Nucleotide Accession #NM_002507