mtTFA (TFAM) Human Gene Knockout Kit (CRISPR)
Cat# KN215488BN
Size : 1kit
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mtTFA (TFAM) Human Gene Knockout Kit (CRISPR)
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | mtTFA |
| Locus ID | 7019 |
| Components | KN215488G1, mtTFA gRNA vector 1 in pCas-Guide CRISPR vector KN215488G2, mtTFA gRNA vector 2 in pCas-Guide CRISPR vector KN215488BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001270782, NM_003201, NM_012251, NR_073073 |
| UniProt ID | Q00059 |
| Synonyms | MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3 |
| Summary | This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
| Shipping | Ambient |
More linear donor DNA can be ordered separately
| Cat# | KN215488BND |
| Description | 10 ug linear donor DNA for KN215488BN kit |
| /€515 |
If you want to order 50ug, please order quantity of 5 for KN215488BND
Other selection marker is available for donor DNA.
Please contact tech@biotrend.com for a custom quote.
| Product Manuals |
| FAQs |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| GA104828 | TFAM CRISPRa kit - CRISPR gene activation of human transcription factor A, mitochondrial | 1 kit | | |
| KN215488 | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN215488LP | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN215488RB | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN415488 | TFAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.