MHC Class 1 (MHC Class I) (Biotin)

Cat# M3885-48Q2-100ul

Size : 100ul

Brand : US Biological

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M3885-48Q2 MHC Class 1 (MHC Class I) (Biotin)

Clone Type
Polyclonal
Host
mouse
Source
mouse
Isotype
IgG2b
Grade
Affinity Purified
Applications
IP
Crossreactivity
Bo Gp Hm Hu Mo Po Rt Sh
Shipping Temp
Blue Ice
Storage Temp
-20°C

MHC Class 1 is expressed at varying levels on the majority of nucleated cells. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.||Applications:|Suitable for use in Flow Cytometry (Not Tested) and Immunoprecipitation. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | |Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG2b|Clone No: 10F80|Host: mouse|Source: mouse|Concentration: As reported |Form: Supplied as a liquid in PBS, pH 7.4. Labeled with Biotin.|Purity: Purified by Protein A affinity chromatography from tissue culture supernatant.|Immunogen: Purified H-2Kb and H-2Db MHC-I molecules.|Specificity: Recognizes the monomorphic epitope present on mouse MHC Class 1. The epitope recognised is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this may recognize a polymorphic epitope of canine MHC class I. Species Crossreactivity: rat, guinea pig, sheep, bovine, porcine, human, hamster. ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Purified H-2Kb and H-2Db MHC-I molecules.
Form
Supplied as a liquid in PBS, pH 7.4. Labeled with Biotin.
Purity
Purified by Protein A affinity chromatography from tissue culture supernatant.
Specificity
Recognizes the monomorphic epitope present on mouse MHC Class 1. The epitope recognised is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this may recognize a polymorphic epitope of canine MHC class I. Species Crossreactivity: rat, guinea pig, sheep, bovine, porcine, human, hamster.