KLRC Family Polyclonal Antibody
Cat# bs-2416R-20ul
Size : 20ul
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KLRC Family Polyclonal Antibody
Image kindly submitted by Shoko Hagen at Oregon Health and Science University.\\n\\nRhesus Macaques PBMCs were stained with 5uL per tube of Rabbit Anti-NKG2C Polyclonal Antibody, FITC Conjugated (bs-2416R-FITC)
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2416R |
| Product Name | KLRC Family Polyclonal Antibody |
| Applications | ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Reactivity | Others, Monkey |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NKG2C |
| Immunogen Range | 51-150/231 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 3822 |
| Swiss Prot | P26717 |
| Subcellular location | Cell membrane |
| Synonyms | KLRC1; NKG2-A/NKG2-B type II integral membrane protein; CD159a; NKG2-A/B-activating NK receptor; NK cell receptor A; NKG2A; NKG2B; KLRC2; NKG2-C type II integral membrane protein; CD159c; NK cell receptor C; NKG2-C-activating NK receptor; NKG2C; KLRC3; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor; NKG2E; KLRC4; NKG2-F type II integral membrane protein; NK cell receptor F; NKG2-F-activating NK receptor; NKG2F. |
| Background | Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| FCM | 1:20-100 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |