OPRB00170 | Interleukin-4 Protein Biotrend

Datasheets/Manuals	Printable datasheet for Interleukin-4 Protein (OPRB00170)

Product Info
Product Format	Liquid
Application	WB
Additional Information	Buffer: Carrier free format presented in 50% glycerol buffered with saline or Tris
Reconstitution and Storage	<=-20C
Purity	>95% by SDS-PAGE

Reference	Ohara, J. (1989) Year Immunol. 5 : 126-159. Beckmann, M.P. et al. (1992) Chem. Immunol. 51 : 107- 134
Gene Symbol	IL4
Alias Symbols	BSF1, IL-4, BCGF1, BSF-1, BCGF-1
NCBI Gene Id	3565
Protein Name	Interleukin-4
Uniprot ID	P05112

Protein interactions

Name	# of Products
A2M	261
CD53	74
IL13RA2	24
IL2RG	89
IL4R	67
PIK3CD	67

Biological pathways

Name	# of Products
B cell differentiation	158
Cellular defense response	219
Chemotaxis	300
Cholesterol metabolic process	142
Connective tissue growth factor biosynthetic process	15
Dendritic cell differentiation	32
Negative regulation of apoptotic process	538
Negative regulation of osteoclast differentiation	65
Negative regulation of transcription, DNA-dependent	660
Positive regulation of B cell proliferation	254
Positive regulation of interleukin-13 production	26
Positive regulation of isotype switching to IgE isotypes	30
Positive regulation of isotype switching to IgG isotypes	88
Positive regulation of MHC class II biosynthetic process	55
Positive regulation of T cell differentiation	59
Positive regulation of transcription from RNA polymerase II promoter	1210
T-helper 2 cell cytokine production	20

Biological process

Name	# of Products
B cell differentiation	46
Cellular defense response	54
Cellular response to mercury ion	8
Chemotaxis	142
Cholesterol metabolic process	72
Connective tissue growth factor biosynthetic process	1
Dendritic cell differentiation	11
Female pregnancy	73
Immune response	404
Innate immune response in mucosa	9
Negative regulation of acute inflammatory response	9
Negative regulation of apoptotic process	356
Negative regulation of chronic inflammatory response	6
Negative regulation of macrophage activation	7
Negative regulation of nitric oxide biosynthetic process	16
Negative regulation of osteoclast differentiation	23
Negative regulation of T cell activation	17
Negative regulation of T-helper 17 cell differentiation	5
Negative regulation of transcription, DNA-dependent	520
Positive regulation of activated T cell proliferation	45
Positive regulation of B cell proliferation	66
Positive regulation of cell proliferation	483
Positive regulation of chemokine biosynthetic process	27
Positive regulation of interleukin-10 production	32
Positive regulation of interleukin-13 production	11
Positive regulation of isotype switching to IgE isotypes	6
Positive regulation of isotype switching to IgG isotypes	27
Positive regulation of MHC class II biosynthetic process	24
Positive regulation of peptidyl-tyrosine phosphorylation	112
Positive regulation of sequence-specific DNA binding transcription factor activity	92
Positive regulation of T cell differentiation	22
Positive regulation of T cell proliferation	93
Positive regulation of transcription from RNA polymerase II promoter	968
Positive regulation of transcription, DNA-dependent	681
Positive regulation of tyrosine phosphorylation of Stat5 protein	37
Regulation of immune response	89
Regulation of inflammatory response	39
Regulation of isotype switching	2
Regulation of phosphorylation	32
Regulation of proton transport	7
Response to cytokine stimulus	73
Response to drug	323
Response to ethanol	105
Response to nutrient	95
Response to organic cyclic compound	128
T-helper 2 cell cytokine production	6
Type 2 immune response	3

Cellular components

Name	# of Products
External side of plasma membrane	261
Extracellular region	1573
Extracellular space	884

Protein function

Name	# of Products
Cytokine activity	1104
Growth factor activity	831
Interleukin-4 receptor binding	35
Protein binding	12191

Interleukin-4 Protein

Cat# OPRB00170

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Brand : Aviva Systems Biology

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