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> Hydroxychloroquine [118-42-3]

Hydroxychloroquine [118-42-3]

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Cat# T9287-100mg

Size : 100mg

Brand : TargetMol

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Hydroxychloroquine

Hydroxychloroquine
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Purity:99.03%
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COA HNMR HPLC

Hydroxychloroquine

Catalog No. T9287Cas No. 118-42-3
Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack Size
50 mg
100 mg
200 mg
500 mg

Product Introduction

Bioactivity
Description
Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
Alias2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol
Chemical Properties
Molecular Weight335.87
FormulaC18H26ClN3O
Cas No.118-42-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 1.65 mg/mL (4.91 mM), Sonication and heating to 60℃ are recommended.
DMSO: < 1 mg/mL (insoluble or slightly soluble)
1M HCl: 99 mg/mL (294.75 mM), when pH is adjusted to 2 with HCl.
Solution Preparation Table
1M HCl/H2O
1mg5mg10mg50mg
1 mM2.9773 mL14.8867 mL29.7734 mL148.8671 mL
1M HCl
1mg5mg10mg50mg
5 mM0.5955 mL2.9773 mL5.9547 mL29.7734 mL
10 mM0.2977 mL1.4887 mL2.9773 mL14.8867 mL
20 mM0.1489 mL0.7443 mL1.4887 mL7.4434 mL
50 mM0.0595 mL0.2977 mL0.5955 mL2.9773 mL
100 mM0.0298 mL0.1489 mL0.2977 mL1.4887 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ParasiteToll-like Receptor (TLR)SARS-CoVInhibitorSARS coronavirusAutophagyinhibitHydroxychloroquine