Human Hexokinase 1 (HK1) activation kit by CRISPRa

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Cat# GA102113

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Human Hexokinase 1 (HK1) activation kit by CRISPRa

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SKU

GA102113

HK1 CRISPRa kit - CRISPR gene activation of human hexokinase 1

Datasheet SDS

Find the corresponding CRISPRi Inhibitor Kit

2 Weeks*

Specifications
Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol	HK1
Locus ID	3098
Components	GA102113G1, Hexokinase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102113G2, Hexokinase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102113G3, Hexokinase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping	Ambient
Reference Data
RefSeq	NM_000188, NM_001322364, NM_001322365, NM_001322366, NM_001322367, NM_033496, NM_033497, NM_033498, NM_033500, NM_001358263
UniProt ID	P19367
Synonyms	hexokinase; HK; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1
Summary	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]

Product Manuals
CRISPR activation (CRISPRa) and CRISPR interference (CRISPRi) Manual
FAQs
FAQ for CRISPR Products
SDS
SDS for GA102113

Gene Expression Resources
4-min CRISPR Quick-Learning Video Video Protocol: Gene Knockout with CRISPR Kit Frequently Asked Questions on CRISPR Webinar from Cell: Expanding CRISPR Toolbox CRISPR Knockout kit manual CRISPR vector manual CRISPR Trangene Knockin at AAVS1 and ROSA26 loci manual CRISPR activation (CRISPRa) and CRISPR interference (CRISPRi) manual HA-Tagging Validation Data qPCR manual Mycoplasma Detection Kit w/ IAC Video Protocol: MycoTrack^TM

SKU	Description	Size
KN200464	HK1 - human gene knockout kit via CRISPR, HDR mediated	1 kit
KN200464BN	HK1 - human gene knockout kit via CRISPR, HDR mediated	1 kit
KN200464LP	HK1 - human gene knockout kit via CRISPR, HDR mediated	1 kit
KN200464RB	HK1 - human gene knockout kit via CRISPR, HDR mediated	1 kit
KN400464	HK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.	1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.