HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]
Cat# AM03005RP-N
Size : 100ug
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| Product Data | |
| Clone Name | W6/32 |
|---|---|
| Application | FC |
| Application | Flow Cytometry (1/50). |
| Reactivity | Bovine, Feline, Human, Primate |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Membrane of human tonsil cells |
| Specificity | The antibody W6/32 recognises virtually all nucleated human cells. It is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody W6/32 is also suitable as a positive control for HLA tissue typing and crossmatching. |
| Buffer | Provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: PE State: Liquid purified Ig fraction Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions |
| Concentration | lot specific |
| Purification | Size-Exclusion Chromatography |
| Conjugation | PE |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Background | HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. |
| Synonyms | MHC class I ABC, HLA Class 2 ABC |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.