HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]
Cat# SM1222R
Size : 100Tests
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| Product Data | |
| Clone Name | W6/32 |
|---|---|
| Application | FC |
| Application | Flow Cytometry: Use 10 μl of neat antibody to label 1x106 cells or 100 μl whole blood. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes. |
| Reactivity | Bovine, Feline, Human, Monkey, Primate |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Purified human tonsil lymphocyte membranes. Spleen cells from immunised BALB/c mice were fused with cells of the NS1/1 - Ag4.1 mouse myeloma cell line. |
| Specificity | Antibody SM1222R recognises an antigenic determinant shared among products of the HLA A, B and C loci. Clone W6/32 recognises a conformational epitope, reacting with HLA class I alpha-3 and alpha-2 domains (See Ishitani, A. et al. for details). MHC class I glycoproteins are found on the surface of almost all nucleated somatic cells. |
| Buffer | PBS Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore with 1ml distilled water |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Background | The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. |
| Synonyms | MHC class I ABC, HLA Class 2 ABC |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.