Guinea pig Polyclonal Anti-Cytokeratin/Keratin14
Cat# 03-GP-CK14-25ul
Size : 25ul
Brand : American Research Products
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Phone : +1 850 650 7790
Anti-Cytokeratin/Keratin14 Polyclonal Antibody
Category: Antibodies
Catalog
03-GP-CK14
| Product Name | Anti-Cytokeratin/Keratin14 Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
| Synonyms | KRT14, K14, NFJ, CK14, EBS3, EBS4 |
| Clonality | Polyclonal |
| Immunogen | Recombinant human keratin K14 (complete polypeptide) |
| Specificity | Acidic keratin K14 (Mr 50 000; formerly also designated cytokeratin 14), expressed in basal and first suprabasal layers of epidermis. The antiserum reacts with keratin K14, expressed in the basal cells of the larynx, esophagus, trachea, bladder, prostate, cervix, vagina, breast acini, skin and sweat glands. |
| Reactivity | Bovine, Human, Mouse |
| Applications | IHC, WB |
| Form | Stabilized Serum |
| Storage | 2-8C |
| References | Demirkesen, C. et al. (1995) J. Cutan. Pathol. 22: 518-535Moll, R. et al. (1995) In: Aktuelle Aspekte der Tumorimmunologie in der Gynaekologie. W. Zuckschwerdt VerlagHoffmann I et al. (2000) J Cell Science 113: 2471-2483Herrmann T et al. (2003) J Cell Biol 161: 1105-1115Langbein L et al. (2003) Eur J Cell Biol 82: 385-400 |
| Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
| Supplier | ARP |
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