GGT5 light chain Polyclonal Antibody, Biotin Conjugated

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Cat# bs-10458R-Biotin

Size : 100ul

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bs-10458R-Biotin [Conjugated Primary Antibody]

GGT5 light chain Polyclonal Antibody, Biotin Conjugated

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Host: Rabbit

Target Protein: GGT5 light chain

Immunogen Range: 388-450/586

Clonality: Polyclonal

Isotype: IgG

Swiss Prot: P36269

Source: KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 light chain

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4; it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)

Predicted Molecular Weight: 22

Predicted Cross Reactive Species: Human
Mouse
Rat
Cow
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS

Zhang Yanli. et al. Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice. NEURAL REGEN RES. 2024 Apr;:10.4103/NRR.NRRRead more>>