FADD Polyclonal Antibody, PE-Cy7 Conjugated
Cat# bs-0511R-PE-Cy7
Size : 100ul
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FADD Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-0511R-PE-Cy7 |
| Product Name | FADD Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications | WB |
| Reactivity | Human, Mouse, Rat, Pig, Monkey |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from mouse FADD |
| Immunogen Range | 1-80/205 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 14082 |
| Swiss Prot | Q61160 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Mort1/FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Protein FADD; Fadd; Mort1 |
| Background | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |