CDKN1A Polyclonal Antibody, PerCP Conjugated
Cat# bs-0741R-PerCP
Size : 100ul
CDKN1A Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-0741r-percp-100ul |
Product Name | CDKN1A Polyclonal Antibody, PerCP Conjugated |
Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Human, Mouse, Rat, Sheep |
Predicted Reactivity | Dog, Cow, Chicken |
Specifications | |
Conjugation | PerCP |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human CDKN1A |
Immunogen Range | 101-164/164 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 12575 |
Swiss Prot | P38936 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP2; Cdkn1; p21WAF; p21Cip1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein; Cdkn1a |
Background | May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |