Anti-CD279 (PD-1) (Human) mAb
Cat# D132-3
Size : 100μg
Contact local distributor :
Please Note: MBL International will be shutting down its operations effective December 31, 2024. Distribution of MBL products in the United States will be transferred to Cosmo Bio US on January 1st while European Distributors will remain unchanged. For any US inquiries regarding orders or support during this transition, reach out to Cosmo Bio: https://www.cosmobiousa.com/. For Non-US inquiries reach out to MBL in Japan: https://www.mblbio.com/.
| Target | PD-1 |
|---|---|
| Product Type | Antibody |
| Application | FCM, WB |
| Clonality | Monoclonal |
| Conjugate | Unlabeled |
| Isotype | IgG1 |
| Immunogen | Fusion protein of human PD-1-Fc |
| Host Species | Mouse |
| Species Reactivity | Human |
| Formulation | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Research Area | Cancer, Immunology |
| Description/Background | Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells. |
| Storage Temperature | -20°C |
| Protocols | FCM, WB |
| Clone Number | J110 |
| Concentration | 1 mg/mL |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
D132-3
Antibody
100 μg