Soluble in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
Shipping Code:
RT
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Size:
Quantity
10 mg
$30.00
50 mg
$50.00
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Adapalene (106685-40-9) is a stable analog of retinoic acid that acts as a selective agonist for RARβ and RARγ. Adapalene also inhibits proliferation and induces apoptosis in colorectal cancer cells in culture.
References/Citations:
1) Michel et al. (1998), Pharmacology of Adapalene; Br. J. Dermatol., 139 Suppl. 52 3 2) Ocker et al. (2003), The synthetic retinoid adapalene inhibits proliferation and induces apoptosis in colorectal cancer cells on vitro; Int. J. Cancer, 107 453 3) Milikan et al. (2000), Adapalene: an update on newer comparative studies between the various retinoids; Int. J. Dermatol., 39 784 4) Bernard et al. (1993), Adapalene, a new chemical entity with retinoid activity; Skin Pharmacol., 6 61
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Adapalene (106685-40-9) is a stable analog of retinoic acid that acts as a selective agonist for RARβ and RARγ. Adapalene also inhibits proliferation and induces apoptosis in colorectal cancer cells in culture.
References/Citations:
1) Michel et al. (1998), Pharmacology of Adapalene; Br. J. Dermatol., 139 Suppl. 52 3 2) Ocker et al. (2003), The synthetic retinoid adapalene inhibits proliferation and induces apoptosis in colorectal cancer cells on vitro; Int. J. Cancer, 107 453 3) Milikan et al. (2000), Adapalene: an update on newer comparative studies between the various retinoids; Int. J. Dermatol., 39 784 4) Bernard et al. (1993), Adapalene, a new chemical entity with retinoid activity; Skin Pharmacol., 6 61
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