SARS-CoV-2 - Spike protein - Primary antibodies
The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.
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RUOCE / IVD
- Unconjugated 1802
- Biotin 45
- HRP 33
- FITC 12
- PE 3
- Alexa Fluor 350 1
- Alexa Fluor 488 1
- Alexa Fluor 555 1
- Alexa Fluor 568 1
- Alexa Fluor 594 1
- Alexa Fluor 647 1
- Alexa Fluor 680 1
- Alexa Fluor 750 1
- Cy7 1
- Gold 1
- virus 1362
- human 159
- mouse 78
- rabbit 4
- all species 3
- monkey 2
- rabbit 712
- mouse 455
- human 357
- llama 40
- goat 23
- chicken 8
- yeast 6
- monkey 2
- sars-cov-2 2
- Primary antibody
- ELISA 1678
- WB 653
- IF 213
- Neutralization 158
- FC 115
- ICC 112
- IP 91
- IHC 58
- Assay 45
- Chemiluminescence 18
- FA 10
- Immunoassay 8
- Dot blot 5
- Blocking 3
- Chromatography 2
- Detection 2
- Lateral Flow 1
- Monoclonal 478
- Polyclonal 403
- S 32
- CR3022 25
- D001 21
- D003 16
- D004 14
- A1 13
- AM122 12
- D006 11
- 5D9 10
- CB6 10
- DM24 10
- DM25 10
- 7 9
- D005 9
- DM39 9
- DM40 9
- DM41 9
- H6 9
- AM130 8
- RH-01 8
- RH-02 8
- 5E8 7
- MAbs in vitro: R107 7
- MAbs in vivo: RBD1106 7
- R007 7
- RBD1125 7
- #41 6
- 118 6
- 43 6
- DM26 6
- DM27 6
- DM35 6
- DM42 6
- 1H2 5
- 4A3 5
- 5A7 5
- ABM19C9 5
- AM001414 (414-1) 5
- AM002414 (414-2) 5
- AM004414 (414-4) 5
- AM043105 (105-43) 5
- OTI1H6 5
- OTI5A7 5
- R00231-234 5
- R00240-242 5
- R00244-246 5
- R00247-250 5
- R00251-254 5
- R00263-266 5
- R00267-270 5
- R00271-274 5
- R00319-322 5
- R00323-326 5
- R00327-330 5
- R00331-334 5
- 1B2 4
- 2146 4
- 2165 4
- 2196 4
- 5.00E+12 4
- ABM5D1.1E8 4
- AD10.F6.G3.E3 4
- DM54 4
- DM55 4
- M89079 4
- #0004 3
- #530 3
- #57 3
- 001 3
- 003 3
- 05 3
- 1 3
- 1.6C7 3
- 117 3
- 135 3
- 16-F-28 3
- 17 3
- 18C7B10 3
- 18H2 3
- 19-J-16 3
- 190 3
- 1A159 3
- 1C2 3
- 1F7 3
- 1G8D11 3
- 1H11 3
- 1H7 3
- 20C3G5 3
- 23-D-12 3
- 235 3
- 27B12 3
- 27C2 3
- 28D9 3
- 28H3 3
- 2B9 3
- 2F1 3
- 30C5 3
- 34-G3 3
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