Optimization buffers - Casein blocking buffers
Why do you need optimization?
- If you have false positive or negative results.
- If you have a specific signal lack due to too much background noise.
Problems with immunoassay results are frequent, with more than 80% of the tests being affected by different types of problems that are independent of the manipulator's level of experience.
These problems can have several sources:
- Matrix Effects
- Cross-reactivity
- Non-specific connections
- HAMAs (human anti-mouse antibodies) or other heterophilic antibodies
- The endogenous proteins present in the tested samples
The perfect solution for interference problems in immunoassays should remove weak to medium affinities without affecting strong affinities.
Optimization solutions are a class of solutions for advantageous and multifunctional immunoassays.
The casein-based surface blocker is also part of the class of optimizers. The blocking solution has exceptional blocking characteristics combined with reduced background noise and high sensitivity of the immunoassay.
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