Anti-CD7 CE/IVD for IHC - Hematopathology

Anti-CD7 CE/IVD for IHC - Hematopathology

 
CD7 is a single-pass type 1 transmembrane protein that is a member of the immunoglobulin superfamily. It plays an essential role in T-cell interactions and also in T-cell/B-cell interactions during early lymphoid development. CD7 is expressed on thymocytes, T- and natural killer cells, and progenitors of lymphoid and myeloid cells. It is also expressed on T-cell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia and Chronic Myelogenous Leukemia. CD7 antibody is the most sensitive and specific T-cell deletion marker. Loss of CD7 expression by neoplastic lymphocytes is considered a distinguishing characteristic of mycosis fungoides (MF) and cutaneous T-cell lymphoma.
Anti-CD7, when used in adjunct with Anti-CD4, is useful for differentiating mycosis fungoides or Sézary syndrome (both cutaneous T-cell lymphomas) from benign dermatoses.
 
 
 
Tonsil section

 

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RUOCE / IVD
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Cat#
Description
Cond.
Price Bef. VAT
IHC541-100
 0.1ml,Concentrated 
IHC541-1
 1ml,Concentrated 
IHC541-7
 7ml,Prediluted