TLR4 Mouse Monoclonal Antibody [Clone ID: HTA125]
Cat# SM1677R
Size : 100Tests
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| Product Data | |
| Clone Name | HTA125 |
|---|---|
| Application | FC |
| Application | Flow Cytometry: Use 10 µl of neat antibody to label 106 cells or 100 µl whole blood. |
| Reactivity | Canine, Guinea Pig, Human, Monkey, Porcine |
| Antibody Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line. |
| Specificity | This antibody recognises the Toll like receptor 4 (TLR4) cell surface antigen. This antibody has been demonstrated to block activation of monocytes with LPS. We recommend the use of SM1677LE for this purpose. |
| Buffer | PBS Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA and 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore with 1.0 ml distilled water. |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | toll like receptor 4 |
| Database Link | |
| Background | TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. |
| Synonyms | Toll-like receptor 4 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.