Rabbit Polyclonal Anti-Uroplakin 3A (Bladder Carcinoma Marker) Polyclonal Antibody
Cat# 24-7380-RBP1-500ul
Size : 500ul
Brand : American Research Products
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Phone : +1 850 650 7790
Anti-Uroplakin 3A (Bladder Carcinoma Marker), Polyclonal Antibody
Category: Antibodies
Catalog
24-7380-RBP1
| Product Name | Anti-Uroplakin 3A (Bladder Carcinoma Marker), Polyclonal Antibody |
|---|---|
| Description | Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. |
| Synonyms | UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A |
| Isotype | IgG |
| Reactivity | Human |
| Applications | FC, IF, WB |
| Form | 200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
| Gene Id | 7380 |
| Uniprot | O75631 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Lai Y et. al. 2010. UPK3A: a promising novel urinary marker for the detection of bladder cancer. Urology 76, 514; 2009 |
| Supplier | ARP |
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