Human Mannose Phosphate Isomerase (MPI) activation kit by CRISPRa
Cat# GA102961
Size : 1kit
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
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Target Symbol | MPI |
Locus ID | 4351 |
Components | GA102961G1, Mannose Phosphate Isomerase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102961G2, Mannose Phosphate Isomerase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102961G3, Mannose Phosphate Isomerase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Shipping | Ambient |
Reference Data | |
RefSeq | NM_001289155, NM_001289156, NM_001289157, NM_002435, NM_001330372 |
UniProt ID | P34949 |
Synonyms | CDG1B; PMI; PMI1 |
Summary | Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Product Manuals |
FAQs |
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SDS |
SKU | Description | Size | ||
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KN408134 | MPI - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
Citations
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