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> CysOx2

CysOx2

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Cat# HY-151505

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Brand : MedChemExpress

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CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells.

For research use only. We do not sell to patients.

CysOx2 Chemical Structure

CysOx2 Chemical Structure

This product is a controlled substance and not for sale in your territory.

Description

CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells[1].

IC50 & Target

Sulfenic acid[1]
In Vitro

CysOx2 (1 mM; 1 h) reacts with H2O2 and produces fluorescence in 50 mM HEPES pH 7.4[1].
CysOx2 is cell permeable[1].
CysOx2 (50 μM; 1 h) shows fluorescence signal in epitope-tagged wild-type EGFR expression HeLa cells, the signal is absent in C797S EGFR expression HeLa cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CysOx2 Related Antibodies
Molecular Weight

305.32

Formula

C15H12FNO3S
SMILES

O=C1CS(=O)(C2=CC(F)=C(C3=CC=CC1=C32)N4CCC4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References

  • [1]. Ferreira RB, et al. Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells. Nat Commun. 2022 Sep 21;13(1):5522.  [Content Brief]

  • [1]. Ferreira RB, et al. Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells. Nat Commun. 2022 Sep 21;13(1):5522.

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CysOx2 Related Classifications

  • Others
  • Others
  • Fluorescent Dye

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CysOx2CysOx 2CysOx-2Fluorescent Dyesulfenic acidliving cellcysteine oxidationfluorogenic probeInhibitorinhibitorinhibit