CD45 Polyclonal Antibody, FITC Conjugated
Cat# bs-0522R-FITC
Size : 100ul
CD45 Polyclonal Antibody, FITC Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-0522R-FITC |
Product Name | CD45 Polyclonal Antibody, FITC Conjugated |
Applications | WB, FCM, IF(IHC-P), IF(ICC) |
Specificity | The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples. |
Reactivity | Human, Mouse, Rat, Rabbit |
Predicted Reactivity | Cow |
Specifications | |
Conjugation | FITC |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human CD45 |
Immunogen Range | 1210-1304/1304 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 5788 |
Swiss Prot | P08575 |
Subcellular location | Cell membrane |
Synonyms | LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC |
Background | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |
Application Dilution | |
WB | 1:300-5000 |
FCM | 1:20-100 |
IF(IHC-P) | 1:50-200 |
IF(ICC) | 1:50-200 |
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