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> β-Amyloid (1-15) [183745-81-5]

β-Amyloid (1-15) [183745-81-5]

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Cat# TP1229-1mg

Size : 1mg

Brand : TargetMol

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Phone : +1 850 650 7790

β-Amyloid (1-15)

β-Amyloid (1-15)
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Purity:99.88%
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COA HPLC MS

β-Amyloid (1-15)

Catalog No. TP1229Cas No. 183745-81-5
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
In vitro
Produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP), β-Amyloid (1-15) appears to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition. It may have several advantages compared to measuring longer cerebrospinal fluid (CSF) Aβ species[1].
AliasAmyloid β-Protein (1-15)
Chemical Properties
Molecular Weight1826.84
FormulaC78H107N25O27
Cas No.183745-81-5
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 30 mg/mL(16.42 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
20 mM0.0274 mL0.1368 mL0.2737 mL1.3685 mL
50 mM0.0109 mL0.0547 mL0.1095 mL0.5474 mL
100 mM0.0055 mL0.0274 mL0.0547 mL0.2737 mL

Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

β Amyloid (1 15)beta-Amyloidb-Amyloid 1-15Amyloid beta-ProteinAmyloid β-Proteinβ-AmyloidAmyloid b-Proteinbeta-Amyloid 1-15b-Amyloidβ-Amyloid 1-15βAmyloid (115)

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