Assay kits for Glucose-6-Phosphate (G6P) detection and quantification are valuable tools for studying glycolysis, carbohydrate metabolism, and related areas such as oxidative stress and diabetes. G6P is a key metabolic intermediate formed during the first step of glycolysis, when glucose is phosphorylated by hexokinase or glucokinase. It also lies at the start of the pentose phosphate pathway and can be stored as glycogen when blood glucose levels are high.
Applications
G6P assay kits find applications in various fields:
- Quantifying G6P in Biological Samples: These kits are used for the quantitative determination of glucose-6-phosphate in biological samples.
- Studying Metabolic Pathways: They are used in research to study glycolysis and the pentose phosphate pathway. G6P lies at the start of these two major metabolic pathways.
- Assessing Oxidative Stress: G6P is utilized by glucose-6-phosphate dehydrogenase (G6PDH) to generate NADPH, which is important for reducing equivalents and combating hemolytic anemia.
- Researching Diabetes and Obesity: These kits are used in research areas such as diabetes and obesity.