Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> Vorinostat [149647-78-9]

Vorinostat [149647-78-9]

Drucken Drucken
Melden Sie sich an

Katalog-Nummer HY-10221-250mg

Size : 250mg

Marke : MedChemExpress

Weitere Informationen anfordern

Contact local distributor :


Telefonnummer : +1 850 650 7790

Vorinostat (SAHA) est un pan-inhibiteur puissant et oralement actif des HDAC1, HDAC2 et HDAC3 (classe I), HDAC7 ( Classe II) et HDAC11 (Classe IV), avec des valeurs ID50 de 10 nM et 20 nM pour HDAC1 et HDAC3, respectivement. Vorinostat induit l'apoptose cellulaire.

Vorinostat (SAHA) ist ein potenter und oral wirksamer Pan-Inhibitor von HDAC1, HDAC2 und HDAC3 (Class I), HDAC7 (Class II) und HDAC11 (Class IV), mit ID50-Werten von 10 nM bzw. 20 nM für HDAC1 und HDAC3. Der Vorinostat induziert die apoptosis.

Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Vorinostat Chemische Struktur

Vorinostat Chemische Struktur

CAS. Nr. : 149647-78-9

This product is a controlled substance and not for sale in your territory.

Based on 112 publication(s) in Google Scholar

Other Forms of Vorinostat:

  • Vorinostat-d5 Angebot einholen
  • Vorinostat (GMP) Angebot einholen
  • Vorinostat (Standard) Angebot einholen

    Vorinostat purchased from MedChemExpress. Usage Cited in: RSC Adv., 2018, 8, 17279-17292

    The NH2 cells expressing Tat. All tested cells are treated with SAHA for 24 h. The expression of GFP for tested J-Lat A2 and 2D10 cells is measured by FACS. Whole cell extracts for tested NH1 and NH2 cells are prepared and examined for the luciferase activities.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Biochim Biophys Acta Gene Regul Mech. 2018 May 18;S1874-9399(18)30028-2.  [Abstract]

    Jurkat T cells are treated for various times with Vorinostat 1 μM and Chidamide at 0.6 μM. Levels of SALL2 and cleaved PARP are evaluated by Western blot analysis. β-actin is used as a loading control.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Nat Commun. 2017 Dec 20;8(1):2207.  [Abstract]

    HCT116 cells are treated with Vorinostat for 24 h, followed by by western blot analysis for the indicated proteins.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Mol Psychiatry. 2017 May;22(5):711-723.  [Abstract]

    Oral SAHA administration increases brain plasma membrane calcium ATPase (PMCA) levels, reduces oxidative stress, improves behavioral deficits and prevents neurodegeneration in ASM knockout (ASMko) mice. (a,b) Western blot of hippocampal membrane extracts from wt (a) and ASMko (b) mice orally administered SAHA complexed to HOP-β-CDX (SAHA) or HOP-β-CDX (control), and probed for PMCA and ATP6V1A.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Biol Pharm Bull. 2017;40(10):1747-1753.  [Abstract]

    Synergistic Decrease Bcl-2 Expression by the Combination of Vorinostat with BMS-354825 in MCF-7 Cells.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Oncotarget. 2017 May 23;8(21):34362-34373.  [Abstract]

    Notch3 protein levels after treatment with SAHA at different concentrations or DMSO (vehicle control), determined by western blot.

    Vorinostat purchased from MedChemExpress. Usage Cited in: Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. 15-06-2015.

    SAHA, a histone deacetylase inhibitor that is shown to increase PMCA levels and to enhance calcium clearance in a breast cancer cell model.

    Alle HDAC Isoform-spezifische Produkte anzeigen:

    Alle Isoformen anzeigen
    HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

    Alle Filovirus Isoform-spezifische Produkte anzeigen:

    Alle Isoformen anzeigen
    EBOV MARV ZEBOV
    Beschreibung

    Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis[1][4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification[7].

    IC50 & Target[1][3][4]

    HDAC1

    10 nM (ID50)

    HDAC3

    20 nM (ID50)

    HDAC2

     

    HDAC7

     

    HDAC11

     

    Autophagy

     

    Mitophagy

     

    Cellular Effect
    Cell Line Type Value Description References
    4T1 IC50
    1.59 μM
    Compound: SAHA
    Antiproliferative activity against mouse 4T1 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against mouse 4T1 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    		[PMID: 33586434]
    4T1 IC50
    12.12 μM
    Compound: SAHA
    Antiproliferative activity against mouse 4T1 cells assessed as cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against mouse 4T1 cells assessed as cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    4T1 IC50
    4.317 μM
    Compound: SAHA
    Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    4T1 IC50
    4.76 μM
    Compound: Vorinostat
    Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    518A2 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    786-0 GI50
    3.2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human 786-0 cells after 72 hrs by MTS assay
    Growth inhibition of human 786-0 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    A2780 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
    Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    A2780 IC50
    0.43 μM
    Compound: 3; SAHA
    Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    A2780 IC50
    0.44 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin resistant human A2780 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin resistant human A2780 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    A2780 IC50
    0.53 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in human A2780 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in human A2780 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    A2780 IC50
    0.64 μM
    Compound: Vorinostat
    Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further incubation for 3 hrs by microplate reader based fluorescence assay
    Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further incubation for 3 hrs by microplate reader based fluorescence assay
    		[PMID: 31431326]
    A2780 IC50
    0.96 μM
    Compound: Vorinostat
    Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay
    Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay
    		[PMID: 31762274]
    A2780 IC50
    1.16 μM
    Compound: Vorinostat
    Antiproliferative activity against human A2780 cells after 72 hrs by microplate reader based MTT assay
    Antiproliferative activity against human A2780 cells after 72 hrs by microplate reader based MTT assay
    		[PMID: 31431326]
    A2780 IC50
    1.62 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human A2780 cells after 96 hrs by celltiter 96 assay
    Antiproliferative activity against human A2780 cells after 96 hrs by celltiter 96 assay
    		[PMID: 21634430]
    A2780 IC50
    2.04 μM
    Compound: 1
    Cytotoxicity against human A2780 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human A2780 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 31787463]
    A2780 IC50
    2.1 μM
    Compound: SAHA
    Antiproliferative activity against human A2780 cells after 72 hrs by SRB assay
    Antiproliferative activity against human A2780 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    A2780 IC50
    2.1 μM
    Compound: SAHA
    Antiproliferative activity against human A2780 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human A2780 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    A2780 IC50
    2.42 μM
    Compound: Vorinostat
    Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 33360560]
    A2780 IC50
    2.42 μM
    Compound: Vorinostat
    Cytotoxicity against human A2780 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
    Cytotoxicity against human A2780 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
    		[PMID: 31762274]
    A2780 IC50
    2.42 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
    Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    A2780 CC50
    2600 nM
    Compound: 1
    Antiproliferative activity against human A2780 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human A2780 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    A2780 IC50
    2600 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human A2780 cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human A2780 cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    A2780 IC50
    3.12 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin resistant human A2780 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin resistant human A2780 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    A2780 GI50
    3150 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human A2780 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human A2780 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    A2780 EC50
    377.48 nM
    Compound: SAHA
    Inhibition of HDAC1/2/3 in human A2780S cells assessed as histone H3 acetylation incubated for 6 hrs by cytoblot assay
    Inhibition of HDAC1/2/3 in human A2780S cells assessed as histone H3 acetylation incubated for 6 hrs by cytoblot assay
    		[PMID: 27186676]
    A2780 EC50
    399.25 nM
    Compound: SAHA
    Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assay
    Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assay
    		[PMID: 27186676]
    A2780 IC50
    8.82 μM
    Compound: SAHA
    Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 37116762]
    A2780 IC50
    870 nM
    Compound: SAHA
    Cytotoxicity against human A2780S cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human A2780S cells assessed as growth inhibition after 24 hrs by MTT assay
    		[PMID: 27186676]
    A2780S IC50
    5541 nM
    Compound: SAHA
    Antiproliferative activity against human A2780S cells after 72 hrs by MTT assay
    Antiproliferative activity against human A2780S cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    A-375 IC50
    2.68 μM
    Compound: SAHA
    Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    		[PMID: 31991336]
    A-375 IC50
    2.827 μM
    Compound: SAHA
    Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    A-375 IC50
    4.1 μM
    Compound: SAHA
    Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 28131715]
    A-431 IC50
    0.63 μM
    Compound: SAHA
    Antiproliferative activity against human A-431 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human A-431 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    A-431 IC50
    1.47 μM
    Compound: Vorinostat
    Antiproliferative activity against human A431 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A431 cells incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    A-431 IC50
    2.29 μM
    Compound: 8
    Antiproliferative activity against human A431 cells expressing EGFR/HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Antiproliferative activity against human A431 cells expressing EGFR/HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    		[PMID: 27769671]
    A-431 IC50
    3.5 μM
    Compound: SAHA
    Antiproliferative activity against human A431 cells after 72 hrs by SRB assay
    Antiproliferative activity against human A431 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    A-431 IC50
    4.2 μM
    Compound: 2a
    Cytotoxicity against human A431 cells overexpressing EGFR by resazurin dye reduction assay
    Cytotoxicity against human A431 cells overexpressing EGFR by resazurin dye reduction assay
    		[PMID: 21080629]
    A-431 GI50
    4.48 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human A431 cells by MTT assay
    Growth inhibition of human A431 cells by MTT assay
    		[PMID: 23601706]
    A-431 IC50
    5.13 μM
    Compound: Zolinza, SAHA
    Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
    		[PMID: 22698782]
    A498 GI50
    1.4 μM
    Compound: SAHA
    Antiproliferative activity against human A498 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human A498 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    A498 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human A498 cells after 72 hrs by MTS assay
    Growth inhibition of human A498 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    A498 IC50
    25.08 μM
    Compound: SAHA
    Antiproliferative activity against human A498 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    Antiproliferative activity against human A498 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    		[PMID: 34111829]
    A549 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    		[PMID: 35272009]
    A549 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
    		[PMID: 34116381]
    A549 IC50
    > 100 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    A549 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    A549 GI50
    > 200 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 19822426]
    A549 GI50
    > 410 nM
    Compound: Vorinostat
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    A549 IC50
    0.59 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    		[PMID: 34237620]
    A549 IC50
    0.6 mM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells after 2 days by MTT assay
    Antiproliferative activity against human A549 cells after 2 days by MTT assay
    		[PMID: 19608304]
    A549 IC50
    0.63 μM
    Compound: 8
    Cytotoxicity against human A549 cells expressing EGFR and KRAS mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells expressing EGFR and KRAS mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
    		[PMID: 27769671]
    A549 IC50
    0.69 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 21733698]
    A549 IC50
    0.74 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    A549 IC50
    0.76 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs
    Antiproliferative activity against human A549 cells after 48 hrs
    		[PMID: 20576572]
    A549 GI50
    0.79 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
    Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
    		[PMID: 21712146]
    A549 IC50
    0.86 μM
    Compound: SAHA
    Anti-proliferative activity against human A549 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    A549 IC50
    0.868 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells by SRB assay
    Cytotoxicity against human A549 cells by SRB assay
    		[PMID: 20855208]
    A549 IC50
    0.89 μM
    Compound: 1
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    A549 EC50
    1 μM
    Compound: SAHA
    Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISA
    Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISA
    		[PMID: 25734520]
    A549 GI50
    1.02 μM
    Compound: 1; SAHA
    Growth inhibition of human A549 cells incubated for 48 hrs by SRB assay
    Growth inhibition of human A549 cells incubated for 48 hrs by SRB assay
    		[PMID: 32058238]
    A549 GI50
    1.02 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
    Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
    		[PMID: 27344487]
    A549 GI50
    1.02 μM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    		[PMID: 31655430]
    A549 GI50
    1.02 μM
    Compound: SAHA; 1
    Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 29567459]
    A549 EC50
    1.03 μM
    Compound: SAHA
    Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assay
    Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assay
    		[PMID: 25238284]
    A549 IC50
    1.079 μM
    Compound: vorinostat
    Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    		[PMID: 26629860]
    A549 IC50
    1.08 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells after 72 hrs by CellTiter-Glo assay
    Cytotoxicity against human A549 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 30245394]
    A549 IC50
    1.08 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human A549 cells after 72 hrs by CellTiter-Glo assay
    Antiproliferative activity against human A549 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 23792316]
    A549 IC50
    1.35 μM
    Compound: Vorinostat
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    A549 IC50
    1.5 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    A549 IC50
    1.54 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    		[PMID: 24766560]
    A549 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human A549/ATCC cells after 72 hrs by MTS assay
    Growth inhibition of human A549/ATCC cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    A549 IC50
    1.65 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    		[PMID: 25953722]
    A549 IC50
    1.65 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    		[PMID: 25874326]
    A549 IC50
    1.67 μM
    Compound: SAHA
    Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
    Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
    		[PMID: 33744687]
    A549 IC50
    1.69 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 35858522]
    A549 IC50
    1.7 μM
    Compound: SAHA
    Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
    Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
    		[PMID: 33744687]
    A549 IC50
    1.7 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    		[PMID: 32738414]
    A549 IC50
    1.7 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 29223096]
    A549 GI50
    1.73 μM
    Compound: 1; SAHA
    Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 28395150]
    A549 GI50
    1.78 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 23601706]
    A549 IC50
    1.8 μM
    Compound: 2a
    Cytotoxicity against human A549 cells overexpressing HDAC by resazurin dye reduction assay
    Cytotoxicity against human A549 cells overexpressing HDAC by resazurin dye reduction assay
    		[PMID: 21080629]
    A549 GI50
    1.85 μM
    Compound: 1, SAHA
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    		[PMID: 22439863]
    A549 EC50
    12 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells measured after 72 hrs by WST1 assay
    Antiproliferative activity against human A549 cells measured after 72 hrs by WST1 assay
    		[PMID: 27597246]
    A549 IC50
    12.46 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		10.1039/C5MD00247H
    A549 IC50
    12.5 nM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
    		[PMID: 32679451]
    A549 IC50
    15.73 μM
    Compound: SAHA
    Antiproliferative activity in human A549 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    Antiproliferative activity in human A549 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    		[PMID: 32061484]
    A549 IC50
    17.9 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23707260]
    A549 IC50
    1746.95 nM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
    Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
    		[PMID: 30115492]
    A549 CC50
    1800 nM
    Compound: 1
    Antiproliferative activity against human P53 expressing A549 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human P53 expressing A549 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    A549 IC50
    1800 nM
    Compound: 1, SAHA
    Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19410459]
    A549 IC50
    1800 nM
    Compound: 1, SAHA
    Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue viability assay
    Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue viability assay
    		[PMID: 18809328]
    A549 IC50
    1800 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human A549 cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human A549 cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    A549 GI50
    19.45 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 28629630]
    A549 IC50
    2.01 μM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
    		[PMID: 30045621]
    A549 IC50
    2.1 μM
    Compound: SAHA
    Antiproliferative against human A549 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative against human A549 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 33045329]
    A549 IC50
    2.2 μM
    Compound: 6, SAHA
    Cytotoxicity against human A549 cells after 72 hrs by alamar-blue cell viability assay
    Cytotoxicity against human A549 cells after 72 hrs by alamar-blue cell viability assay
    		[PMID: 19301902]
    A549 IC50
    2.24 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 30525585]
    A549 IC50
    2.27 μM
    Compound: Vorinostat
    Cytotoxicity against human A549 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    Cytotoxicity against human A549 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    		[PMID: 23829483]
    A549 IC50
    2.36 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    A549 IC50
    2.39 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    		[PMID: 28987602]
    A549 IC50
    2.42 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
    		[PMID: 31413795]
    A549 IC50
    2.61 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    A549 GI50
    2.62 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
    		[PMID: 31924504]
    A549 IC50
    2.63 μM
    Compound: 4; SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
    		[PMID: 29670692]
    A549 IC50
    2.79 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    A549 IC50
    2.9 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells by CCK8 assay
    Antiproliferative activity against human A549 cells by CCK8 assay
    		[PMID: 30660827]
    A549 IC50
    2.93 μM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    		[PMID: 32180916]
    A549 IC50
    2651.1 nM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    		[PMID: 32679451]
    A549 IC50
    27.8 μM
    Compound: Zolinza, SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 22698782]
    A549 GI50
    3.1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human A549 cells after 72 hrs by MTT assay
    Growth inhibition of human A549 cells after 72 hrs by MTT assay
    		[PMID: 22435669]
    A549 GI50
    3.13 μM
    Compound: 1, SAHA
    Growth inhibition of human A549 cells after 96 hrs by MTT assay
    Growth inhibition of human A549 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    A549 IC50
    3.14 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells incubated for 96 hrs by resazurin assay
    Antiproliferative activity against human A549 cells incubated for 96 hrs by resazurin assay
    		[PMID: 32435375]
    A549 IC50
    3.5 μM
    Compound: 2; SAHA
    Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 34634618]
    A549 IC50
    3.7 μM
    Compound: Vorinostat
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    A549 IC50
    3.7 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs
    Antiproliferative activity against human A549 cells after 48 hrs
    		[PMID: 24262004]
    A549 IC50
    3.8 μM
    Compound: 1, SAHA
    Inhibition of human A549 cell proliferation after 48 hrs by MTT assay
    Inhibition of human A549 cell proliferation after 48 hrs by MTT assay
    		[PMID: 23493449]
    A549 IC50
    3.9 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    A549 IC50
    3.9 μM
    Compound: SA, SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    A549 IC50
    4.12 μM
    Compound: 1; SAHA
    Cytotoxicity against human A549 cells assessed as decrease in cell viability measured after 72 hrs by CellTiter-Glo Luminescent assay
    Cytotoxicity against human A549 cells assessed as decrease in cell viability measured after 72 hrs by CellTiter-Glo Luminescent assay
    		[PMID: 31223439]
    A549 IC50
    4.25 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    A549 IC50
    4.3 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    		[PMID: 34624191]
    A549 IC50
    4.372 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    		[PMID: 34454126]
    A549 IC50
    4.4 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    		[PMID: 35608269]
    A549 IC50
    4.4 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    		[PMID: 29348808]
    A549 IC50
    4.5 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 23570542]
    A549 IC50
    4.97 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    A549 IC50
    476.86 nM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells measured after 48 hrs by sulforhodamine-B assay
    Antiproliferative activity against human A549 cells measured after 48 hrs by sulforhodamine-B assay
    		[PMID: 27886544]
    A549 IC50
    5 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    A549 IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells by MTT assay
    Antiproliferative activity against human A549 cells by MTT assay
    		[PMID: 31546197]
    A549 GI50
    5.02 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells after 96 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 96 hrs by MTT assay
    		[PMID: 29500130]
    A549 GI50
    5.27 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    A549 IC50
    5.32 μM
    Compound: SAHA
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26149591]
    A549 IC50
    5.37 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		10.1039/C5MD00247H
    A549 GI50
    5.4 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    		[PMID: 34500130]
    A549 IC50
    5.74 μM
    Compound: I-1; SAHA
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 35245830]
    A549 GI50
    5700 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human A549 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human A549 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    A549 IC50
    7.06 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK8 assay
    		[PMID: 32247729]
    A549 IC50
    7.32 μM
    Compound: 1; SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 34656899]
    A549 IC50
    7.44 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    		[PMID: 35043615]
    A549 IC50
    7.49 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells measured after 72 hrs
    Antiproliferative activity against human A549 cells measured after 72 hrs
    		[PMID: 35697181]
    A549 IC50
    78.76 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		10.1039/C5MD00247H
    A549 EC50
    8.3 μM
    Compound: SAHA
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 23820574]
    A549 IC50
    80.3 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against SAHA-resistant human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against SAHA-resistant human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 23707260]
    A549 IC50
    9.13 μM
    Compound: Vorinostat
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    		[PMID: 35255412]
    ACHN GI50
    0.65 μM
    Compound: SAHA
    Growth inhibition of human ACHN cells after 21 hrs by MTT assay
    Growth inhibition of human ACHN cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    ACHN GI50
    0.73 μM
    Compound: 1, SAHA
    Growth inhibition of ACHN cells by SRB assay
    Growth inhibition of ACHN cells by SRB assay
    		[PMID: 17477518]
    ACHN GI50
    0.73 μM
    Compound: 2, SAHA
    Antiproliferative activity against human ACHN cells by SRB assay
    Antiproliferative activity against human ACHN cells by SRB assay
    		[PMID: 16723227]
    ACHN GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human ACHN cells after 72 hrs by MTS assay
    Growth inhibition of human ACHN cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    ACHN IC50
    2.08 μM
    Compound: SAHA
    Antiproliferative activity against human ACHN cells after 72 hrs by MTT assay
    Antiproliferative activity against human ACHN cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    ACHN GI50
    2.22 μM
    Compound: 2, SAHA
    Growth inhibition of human ACHN cells by SRB assay
    Growth inhibition of human ACHN cells by SRB assay
    		[PMID: 17904843]
    ACHN GI50
    4.22 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human ACHN cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human ACHN cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    ACHN GI50
    4.22 μM
    Compound: SAHA
    Growth inhibition of human ACHN cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human ACHN cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    ACHN GI50
    4.22 μM
    Compound: SAHA
    Growth inhibition of human ACHN cells after 5 days by sulforhodamine B assay
    Growth inhibition of human ACHN cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    AGS IC50
    4 μM
    Compound: SAHA
    Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    AGS IC50
    4.23 μM
    Compound: SAHA
    Antiproliferative activity against human AGS cells after 72 hrs by MTT assay
    Antiproliferative activity against human AGS cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    ASPC1 IC50
    > 411 nM
    Compound: Vorinostat
    Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    ASPC1 GI50
    2.09 μM
    Compound: 1, SAHA
    Growth inhibition of human Aspc-1 cells after 96 hrs by MTT assay
    Growth inhibition of human Aspc-1 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    ASPC1 IC50
    3.09 μM
    Compound: SAHA
    Antiproliferative activity against human ASPC1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human ASPC1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    ASPC1 IC50
    3.2 μM
    Compound: SAHA
    Antiproliferative activity against human Aspc-1 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human Aspc-1 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 31546197]
    ASPC1 IC50
    3.2 μM
    Compound: Vorinostat
    Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    ASPC1 IC50
    3.66 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human AsPC1 cells after 48 hrs by SRB assay
    Antiproliferative activity against human AsPC1 cells after 48 hrs by SRB assay
    		[PMID: 24185378]
    ASPC1 GI50
    5.44 μM
    Compound: 1; SAHA
    Growth inhibition of human AsPC1 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human AsPC1 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 28395150]
    B16 IC50
    2.26 μM
    Compound: I-1; SAHA
    Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
    Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
    		[PMID: 35245830]
    B16 IC50
    4.44 μM
    Compound: 1, SAHA
    Cytotoxicity against mouse B16 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against mouse B16 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    B16-F10 IC50
    11.36 μM
    Compound: SAHA
    Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    		[PMID: 35043615]
    B16-F10 IC50
    13.1 μM
    Compound: SAHA
    Cytotoxicity against mouse B16F10 cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against mouse B16F10 cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 28131715]
    B16-F10 IC50
    13.52 μM
    Compound: SAHA
    Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    B16-F10 IC50
    2.067 μM
    Compound: SAHA
    Cytotoxicity against human B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    Bcap37 IC50
    3.098 μM
    Compound: SAHA
    Cytotoxicity against human Bcap37 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    BE(2)-C IC50
    1.1 μM
    Compound: SAHA
    Antiproliferative activity against human BE(2)-C cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human BE(2)-C cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25238284]
    BE(2)-C IC50
    2 μM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human BE(2)-C cells after 72 hrs by Alamar blue assay
    Antiproliferative activity against human BE(2)-C cells after 72 hrs by Alamar blue assay
    		[PMID: 22932316]
    BEAS-2B IC50
    > 50 μM
    Compound: 1; SAHA
    Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability after 48 hrs by SRB assay
    Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability after 48 hrs by SRB assay
    		[PMID: 32180916]
    Bel-7402 IC50
    27.35 μM
    Compound: SAHA
    Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    Bel-7402 IC50
    4.207 μM
    Compound: SAHA
    Cytotoxicity against human Bel-7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human Bel-7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    Bel-7402 IC50
    4.7 μM
    Compound: SAHA
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    		[PMID: 31120744]
    Bel-7402 IC50
    4.72 μM
    Compound: SAHA
    Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    Bel-7402 IC50
    7.1 μM
    Compound: 5; SAHA
    Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    Bel7402/5-FU IC50
    9.83 μM
    Compound: SAHA
    Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    BGC-823 IC50
    12.98 μM
    Compound: SAHA
    Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    BGC-823 IC50
    2.94 μM
    Compound: SAHA
    Antiproliferative activity against human BGC823 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    BGC-823 GI50
    3.09 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human BGC823 cells by MTT assay
    Growth inhibition of human BGC823 cells by MTT assay
    		[PMID: 23601706]
    BGC-823 GI50
    4.26 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human BGC823 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human BGC823 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    BJ IC50
    > 100 μM
    Compound: SAHA
    Growth inhibition of human BJ cells after 48 hrs by MTT assay
    Growth inhibition of human BJ cells after 48 hrs by MTT assay
    		[PMID: 20143840]
    BMDM CC50
    5 μM
    Compound: 1
    Cytotoxicity against Swiss mouse BMDM assessed as reduction in cell viability measured after 72 hrs by tryphan blue assay
    Cytotoxicity against Swiss mouse BMDM assessed as reduction in cell viability measured after 72 hrs by tryphan blue assay
    		[PMID: 32392053]
    BT-474 IC50
    2.67 μM
    Compound: 8
    Cytotoxicity against human BT474 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human BT474 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    		[PMID: 27769671]
    BT-549 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human BT549 cells after 72 hrs by MTS assay
    Growth inhibition of human BT549 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    BT-549 IC50
    2.96 μM
    Compound: SAHA
    Antiproliferative activity against human BT-549 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human BT-549 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    		[PMID: 33586434]
    BT-549 IC50
    8.67 μM
    Compound: SAHA
    Cytotoxicity against human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    BXPC-3 IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human BxPC3 cells after hrs by ATP content assay
    Antiproliferative activity against human BxPC3 cells after hrs by ATP content assay
    		[PMID: 20143778]
    BXPC-3 IC50
    4.74 μM
    Compound: SAHA
    Antiproliferative activity against human BXPC-3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human BXPC-3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    BXPC-3 IC50
    5 μM
    Compound: 1a, SAHA
    Growth inhibition of human BxPC3 cells after 72 hrs by MTS assay
    Growth inhibition of human BxPC3 cells after 72 hrs by MTS assay
    		[PMID: 20055418]
    BXPC-3 IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against human BxPC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human BxPC3 cells after 72 hrs by MTT assay
    		[PMID: 18642892]
    BXPC-3 IC50
    5 μM
    Compound: SAHA
    Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay
    Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay
    		[PMID: 18494463]
    BXPC-3 IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against human BxPC3 cells by MTT assay
    Antiproliferative activity against human BxPC3 cells by MTT assay
    		[PMID: 19419863]
    BXPC-3 GI50
    5.56 μM
    Compound: Vorin
    Cytotoxicity against human BxPC3 cells after 72 hrs by MTS assay
    Cytotoxicity against human BxPC3 cells after 72 hrs by MTS assay
    		[PMID: 24900743]
    Caco-2 IC50
    0.037 μM
    Compound: SAHA
    Induction of HDAC-mediated histone acetylation in human Caco-2 cells at 5 uM after 6 hrs by indirect ELISA
    Induction of HDAC-mediated histone acetylation in human Caco-2 cells at 5 uM after 6 hrs by indirect ELISA
    		[PMID: 20143840]
    Caco-2 IC50
    0.119 μM
    Compound: SAHA
    Ex vivo inhibition of human HDAC1 in human Caco-2 cells by fluorometric cellular activity assay
    Ex vivo inhibition of human HDAC1 in human Caco-2 cells by fluorometric cellular activity assay
    		[PMID: 20143840]
    Caco-2 IC50
    0.147 μM
    Compound: SAHA
    Ex vivo inhibition of human HDAC3 in human Caco-2 cells by fluorometric cellular activity assay
    Ex vivo inhibition of human HDAC3 in human Caco-2 cells by fluorometric cellular activity assay
    		[PMID: 20143840]
    Caco-2 IC50
    12.6 μM
    Compound: SAHA
    Ex vivo inhibition of human HDAC5 in human Caco-2 cells by fluorometric cellular activity assay
    Ex vivo inhibition of human HDAC5 in human Caco-2 cells by fluorometric cellular activity assay
    		[PMID: 20143840]
    Caco-2 IC50
    3 μM
    Compound: SAHA
    Cytotoxicity against human Caco2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Caco2 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    Caco-2 IC50
    41 μM
    Compound: SAHA
    Ex vivo inhibition of human HDAC7 in human Caco-2 cells by fluorometric cellular activity assay
    Ex vivo inhibition of human HDAC7 in human Caco-2 cells by fluorometric cellular activity assay
    		[PMID: 20143840]
    Caco-2 IC50
    8.1 μM
    Compound: SAHA
    Growth inhibition of human Caco-2 cells after 48 hrs by MTT assay
    Growth inhibition of human Caco-2 cells after 48 hrs by MTT assay
    		[PMID: 20143840]
    CAKI-1 GI50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human Caki1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human Caki1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    CAKI-1 IC50
    32.46 μM
    Compound: SAHA
    Antiproliferative activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    Antiproliferative activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    		[PMID: 34111829]
    CAL-27 IC50
    0.36 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin sensitive human CAL27 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin sensitive human CAL27 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    CAL-27 IC50
    0.61 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin resistant human CAL27 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin resistant human CAL27 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    CAL-27 IC50
    1.5 μM
    Compound: 1
    Cytotoxicity against human CAL27 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human CAL27 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 31787463]
    CAL-27 IC50
    1.96 μM
    Compound: Vorinostat
    Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM)
    Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM)
    		[PMID: 31762274]
    CAL-27 IC50
    1.98 μM
    Compound: Vorinostat
    Antiproliferative activity against human CAL-27 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human CAL-27 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 33360560]
    CAL-27 IC50
    1.98 μM
    Compound: Vorinostat
    Antiproliferative activity against human CAL27 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human CAL27 cells measured after 72 hrs by MTT assay
    		[PMID: 28581289]
    CAL-27 IC50
    1.99 μM
    Compound: Vorinostat
    Antiproliferative activity against human CAL27 cells after 72 hrs by microplate reader based MTT assay
    Antiproliferative activity against human CAL27 cells after 72 hrs by microplate reader based MTT assay
    		[PMID: 31431326]
    CAL-27 IC50
    2.08 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin resistant human CAL27 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin resistant human CAL27 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    CAL-27 IC50
    2.64 μM
    Compound: Vorinostat
    Cytotoxicity against human CAL27 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
    Cytotoxicity against human CAL27 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
    		[PMID: 31762274]
    CAL-27 IC50
    2.64 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin sensitive human CAL27 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin sensitive human CAL27 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    CAL-27 IC50
    3.2 μM
    Compound: 2a
    Cytotoxicity against human CAL27 cells overexpressing EGFR by resazurin dye reduction assay
    Cytotoxicity against human CAL27 cells overexpressing EGFR by resazurin dye reduction assay
    		[PMID: 21080629]
    CAL-51 IC50
    1.04 μM
    Compound: SAHA
    Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    		[PMID: 33586434]
    CAPAN-1 IC50
    1.8 μM
    Compound: SAHA
    Antiproliferative activity against human Capan1 cells after 72 hrs by SRB assay
    Antiproliferative activity against human Capan1 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    CAPAN-1 IC50
    7.3 μM
    Compound: SAHA
    Antiproliferative activity against human Capan1 cells after hrs by ATP content assay
    Antiproliferative activity against human Capan1 cells after hrs by ATP content assay
    		[PMID: 20143778]
    Capan-2 IC50
    3 μM
    Compound: 5; SAHA
    Antiproliferative activity against human Capan2 cells after 96 hrs by MTT assay
    Antiproliferative activity against human Capan2 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    CCRF-CEM GI50
    0.7 μM
    Compound: SAHA
    Antiproliferative activity against human CCRF-CEM cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human CCRF-CEM cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    CCRF-CEM GI50
    0.8 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human CCRF-CEM cells after 72 hrs by MTS assay
    Growth inhibition of human CCRF-CEM cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    CCRF-CEM IC50
    0.8 μM
    Compound: 6, SAHA
    Cytotoxicity against human CCRF-CEM cells after 72 hrs by alamar-blue cell viability assay
    Cytotoxicity against human CCRF-CEM cells after 72 hrs by alamar-blue cell viability assay
    		[PMID: 19301902]
    CCRF-CEM CC50
    2.5 μM
    Compound: SAHA
    Cytotoxicity against human CEM cells assessed as cell death incubated for 20 hrs measured by DNS assay
    Cytotoxicity against human CEM cells assessed as cell death incubated for 20 hrs measured by DNS assay
    		[PMID: 34006099]
    CHP-134 IC50
    1.74 μM
    Compound: Vorinostat
    Antiproliferative activity against human CHP134 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    Antiproliferative activity against human CHP134 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    		[PMID: 31391882]
    CMK IC50
    439.3 nM
    Compound: SAHA
    Antiproliferative activity against human CMK cells after 72 hrs by MTT assay
    Antiproliferative activity against human CMK cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    CMK IC50
    490.2 nM
    Compound: SAHA
    Antiproliferative activity against Ara-C resistant human CMK cells after 72 hrs by MTT assay
    Antiproliferative activity against Ara-C resistant human CMK cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    CNE-2 IC50
    1.3 μM
    Compound: SAHA
    Antiproliferative activity against human CNE-2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human CNE-2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    COLO 205 GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
    Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    COLO 205 IC50
    1.8 μM
    Compound: SAHA
    Cytotoxicity against human COLO205 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human COLO205 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    COLO 205 IC50
    2.12 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter 96 assay
    Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter 96 assay
    		[PMID: 21634430]
    COLO 205 IC50
    2.9 μM
    Compound: SAHA
    Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter assay
    Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter assay
    		[PMID: 19181524]
    COLO 205 GI50
    4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
    Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    COR-L23 GI50
    1100 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human COR-L23 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human COR-L23 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    COR-L23 GI50
    3300 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against doxorubicin-resistant human COR-L23 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against doxorubicin-resistant human COR-L23 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    CT26 GI50
    2.35 μM
    Compound: 3; SAHA
    Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK-8 assay
    Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK-8 assay
    		[PMID: 35390714]
    CT26 GI50
    2.7 μM
    Compound: 7; SAHA
    Antiproliferative activity against mouse CT26 cells measured after 72 hrs by CCK8 assay
    Antiproliferative activity against mouse CT26 cells measured after 72 hrs by CCK8 assay
    		[PMID: 34783558]
    CT26 IC50
    5.65 μM
    Compound: I-1; SAHA
    Antiproliferative activity against mouse CT26 cells after 72 hrs by MTT assay
    Antiproliferative activity against mouse CT26 cells after 72 hrs by MTT assay
    		[PMID: 35245830]
    CT26 IC50
    5.97 μM
    Compound: 4; SAHA
    Antiproliferative activity against mouse CT26 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against mouse CT26 cells after 48 hrs by CCK-8 assay
    		[PMID: 29670692]
    DG-75 IC50
    2.1 μM
    Compound: SAHA
    Antiproliferative activity against human DG75 cells after 72 hrs by MTT assay
    Antiproliferative activity against human DG75 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    DLD-1 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human DLD1 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    Antiproliferative activity against human DLD1 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    		[PMID: 32153186]
    DLD-1 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human DLD-1 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human DLD-1 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    DMS-114 GI50
    2.9 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human DMS114 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human DMS114 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    DU-145 IC50
    0.79 μM
    Compound: 1; SAHA
    Antiproliferative activity against human DU-145 cells incubated for 48 hrs by Sulforhodamine B staining method
    Antiproliferative activity against human DU-145 cells incubated for 48 hrs by Sulforhodamine B staining method
    		[PMID: 33077264]
    DU-145 IC50
    0.87 μM
    Compound: SAHA
    Antiproliferative activity against human DU145 cells after 72 hrs by SRB assay
    Antiproliferative activity against human DU145 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    DU-145 IC50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33965842]
    DU-145 IC50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    		[PMID: 25993269]
    DU-145 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human DU145 cells after 72 hrs by MTS assay
    Growth inhibition of human DU145 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    DU-145 GI50
    1.36 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
    Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    DU-145 IC50
    1.8 μM
    Compound: 5; SAHA
    Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    DU-145 GI50
    1050 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human DU145 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human DU145 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    DU-145 GI50
    1590 nM
    Compound: SAHA
    Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay
    		[PMID: 26331334]
    DU-145 EC50
    2.11 μM
    Compound: SAHA
    Viability of human DU145 cells after 72 hrs by MTS assay
    Viability of human DU145 cells after 72 hrs by MTS assay
    		[PMID: 18397827]
    DU-145 IC50
    2.12 μM
    Compound: SAHA, Vorinostat
    Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    		[PMID: 23622981]
    DU-145 IC50
    2.12 μM
    Compound: SAHA
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    DU-145 EC50
    2.12 μM
    Compound: SAHA
    Viability of human DU145 cells after 72 hrs by trypan blue staining
    Viability of human DU145 cells after 72 hrs by trypan blue staining
    		[PMID: 18397827]
    DU-145 EC50
    2.12 μM
    Compound: SAHA
    Cytotoxicity against human DU145 cells after 72 hrs by trypan blue exclusion assay
    Cytotoxicity against human DU145 cells after 72 hrs by trypan blue exclusion assay
    		[PMID: 19093884]
    DU-145 IC50
    2.49 μM
    Compound: SAHA
    Cytotoxicity against androgen-independent human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against androgen-independent human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 24304348]
    DU-145 IC50
    2.58 μM
    Compound: Vorinostat
    Cytotoxicity against human DU145 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    Cytotoxicity against human DU145 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    		[PMID: 23829483]
    DU-145 IC50
    27.2 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23707260]
    DU-145 IC50
    3.45 μM
    Compound: SAHA
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    DU-145 IC50
    3.7 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against ERalpha-deficient human DU145 cells expressing ERbeta assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against ERalpha-deficient human DU145 cells expressing ERbeta assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23786452]
    DU-145 GI50
    6.86 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human DU145 cells by MTT assay
    Growth inhibition of human DU145 cells by MTT assay
    		[PMID: 23601706]
    EA.hy 926 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    EB-3 GI50
    2.8 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human EB3 cells assessed as growth inhibition incubated for 3 days by MTT assay
    Antiproliferative activity against human EB3 cells assessed as growth inhibition incubated for 3 days by MTT assay
    		10.1039/C4MD00252K
    EB-3 GI50
    2.8 μM
    Compound: 1, SAHA
    Cytotoxic activity against human EB3 cells after 3 days by MTT assay
    Cytotoxic activity against human EB3 cells after 3 days by MTT assay
    		[PMID: 25380299]
    EBC-1 IC50
    1.3 μM
    Compound: SAHA
    Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
    Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
    		[PMID: 28835797]
    EJ IC50
    5.46 μM
    Compound: Vorinostat
    Cytotoxicity against human EJ cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human EJ cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    EKVX GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human EKVX cells after 72 hrs by MTS assay
    Growth inhibition of human EKVX cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    EOL1 IC50
    1 μM
    Compound: 6, SAHA
    Cytotoxicity against human EOL-1 cells after 72 hrs by alamar-blue cell viability assay
    Cytotoxicity against human EOL-1 cells after 72 hrs by alamar-blue cell viability assay
    		[PMID: 19301902]
    Epithelial cell IC50
    14000 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human renal epithelial cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human renal epithelial cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    ES-2 IC50
    0.53 μM
    Compound: SAHA
    Antiproliferative activity against human ES2 cells assessed as reduction in cell viability measured after 7 days
    Antiproliferative activity against human ES2 cells assessed as reduction in cell viability measured after 7 days
    		[PMID: 35643262]
    FHC IC50
    2.59 μM
    Compound: Vorinostat
    Cytotoxicity against human FHC cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human FHC cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    Fibroblast EC50
    > 10 μM
    Compound: SAHA
    Cytotoxicity against human primary lung fibroblasts after 72 hrs by trypan blue exclusion assay
    Cytotoxicity against human primary lung fibroblasts after 72 hrs by trypan blue exclusion assay
    		[PMID: 19093884]
    G-401 CC50
    1000 nM
    Compound: 1
    Antiproliferative activity against human G401 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human G401 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    G-401 IC50
    1000 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human G401 cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human G401 cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    G55T2 IC50
    0.78 μM
    Compound: Vorinostat
    Antiproliferative activity against human G55T2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human G55T2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 31391882]
    GES1 IC50
    233 μM
    Compound: SAHA
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    GES1 IC50
    4690 nM
    Compound: SAHA
    Antiproliferative activity against human GES-1 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human GES-1 cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    HAL-01 IC50
    0.299 μM
    Compound: Vorinostat
    Cytotoxicity against human HAL-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    Cytotoxicity against human HAL-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    		[PMID: 36351184]
    HCC 2998 GI50
    1.9 μM
    Compound: SAHA
    Antiproliferative activity against human HCC2998 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human HCC2998 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    HCC1937 IC50
    4.23 μM
    Compound: SAHA
    Antiproliferative activity against human HCC1937 cells after 3 days by MTT assay
    Antiproliferative activity against human HCC1937 cells after 3 days by MTT assay
    		[PMID: 28601509]
    HCC827 IC50
    1.18 μM
    Compound: SAHA
    Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    HCC827 IC50
    1.8 μM
    Compound: SAHA
    Antiproliferative activity against human HCC827 cells after hrs by ATP content assay
    Antiproliferative activity against human HCC827 cells after hrs by ATP content assay
    		[PMID: 20143778]
    HCCLM3 IC50
    6.52 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCCLM3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCCLM3 cells after 48 hrs by MTT assay
    		[PMID: 30455152]
    HCT-116 IC50
    < 1 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 29954683]
    HCT-116 IC50
    < 1.18 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		10.1039/C5MD00247H
    HCT-116 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    		[PMID: 32153186]
    HCT-116 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    HCT-116 GI50
    > 410 nM
    Compound: Vorinostat
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    HCT-116 IC50
    0.08 mM
    Compound: Vorinostat
    Antiproliferative activity against human HCT116 cells after 2 days by MTT assay
    Antiproliferative activity against human HCT116 cells after 2 days by MTT assay
    		[PMID: 19608304]
    HCT-116 GI50
    0.15 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by SRB assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by SRB assay
    		[PMID: 27344487]
    HCT-116 GI50
    0.15 μM
    Compound: SAHA; 1
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 29567459]
    HCT-116 IC50
    0.27 μM
    Compound: 1
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    HCT-116 IC50
    0.31 μM
    Compound: SAHA
    Antiproliferative activity human HCT116 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    Antiproliferative activity human HCT116 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    		[PMID: 26890116]
    HCT-116 IC50
    0.31 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs
    Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs
    		[PMID: 24742384]
    HCT-116 IC50
    0.31 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs
    Antiproliferative activity against human HCT116 cells after 72 hrs
    		[PMID: 19084294]
    HCT-116 IC50
    0.33 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    HCT-116 IC50
    0.34 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 21733698]
    HCT-116 GI50
    0.37 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
    Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    HCT-116 GI50
    0.4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
    Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    HCT-116 GI50
    0.4 μM
    Compound: 2, SAHA, Vorinostat
    Cytotoxicity against human HCT116 cells after 96 hrs by MTS-PMS assay
    Cytotoxicity against human HCT116 cells after 96 hrs by MTS-PMS assay
    		[PMID: 24164245]
    HCT-116 GI50
    0.44 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
    		[PMID: 31924504]
    HCT-116 IC50
    0.49 μM
    Compound: 3; SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    HCT-116 IC50
    0.55 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    		[PMID: 32738414]
    HCT-116 GI50
    0.55 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    		[PMID: 31655430]
    HCT-116 EC50
    0.57 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 23820574]
    HCT-116 GI50
    0.58 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    HCT-116 IC50
    0.6 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
    		[PMID: 25746815]
    HCT-116 IC50
    0.6 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
    		[PMID: 22877635]
    HCT-116 GI50
    0.6 μM
    Compound: SAHA
    Growth inhibition of human HCT116 cells after 5 days by alamar blue assay
    Growth inhibition of human HCT116 cells after 5 days by alamar blue assay
    		[PMID: 21978679]
    HCT-116 IC50
    0.6 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar blue assay
    Antiproliferative activity against human HCT116 cells after 5 days by Alamar blue assay
    		[PMID: 21420859]
    HCT-116 GI50
    0.6 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 20605448]
    HCT-116 IC50
    0.61 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 24766560]
    HCT-116 GI50
    0.65 μM
    Compound: Vorinostat
    Growth inhibition of human HCT116 cells after 72 hrs by CellTiter Glo assay
    Growth inhibition of human HCT116 cells after 72 hrs by CellTiter Glo assay
    		[PMID: 25182565]
    HCT-116 IC50
    0.67 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    HCT-116 IC50
    0.7 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay
    		[PMID: 21745740]
    HCT-116 IC50
    0.757 μM
    Compound: vorinostat
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    		[PMID: 26629860]
    HCT-116 IC50
    0.76 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
    Cytotoxicity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 30245394]
    HCT-116 IC50
    0.76 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 23792316]
    HCT-116 IC50
    0.79 mM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 20171895]
    HCT-116 IC50
    0.797 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    		[PMID: 35272009]
    HCT-116 IC50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
    		[PMID: 24095018]
    HCT-116 IC50
    0.877 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 29100734]
    HCT-116 GI50
    0.878 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 48 hrs by Sulforhodamine B assay
    Cytotoxicity against human HCT116 cells after 48 hrs by Sulforhodamine B assay
    		[PMID: 23639537]
    HCT-116 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HCT-116 GI50
    0.94 μM
    Compound: 1, SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 24119555]
    HCT-116 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 29100734]
    HCT-116 GI50
    1 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 23538115]
    HCT-116 IC50
    1 μM
    Compound: Vorinostat
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
    		[PMID: 30660827]
    HCT-116 IC50
    1.03 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    HCT-116 GI50
    1.04 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 25800646]
    HCT-116 IC50
    1.08 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    HCT-116 IC50
    1.18 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by CCK8 assay
    		[PMID: 30045621]
    HCT-116 IC50
    1.18 μM
    Compound: SAHA
    Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    HCT-116 IC50
    1.2 μM
    Compound: 2, SAHA
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    		[PMID: 21073160]
    HCT-116 IC50
    1.2 μM
    Compound: SAHA, vorinostat
    Growth inhibition of human HCT116 cells by SRB assay
    Growth inhibition of human HCT116 cells by SRB assay
    		[PMID: 17892933]
    HCT-116 IC50
    1.2 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 24 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT116 cells after 24 hrs by sulforhodamine B assay
    		[PMID: 19359173]
    HCT-116 IC50
    1.2 μM
    Compound: SAHA
    Growth inhibition of human HCT116 cells after 72 hrs
    Growth inhibition of human HCT116 cells after 72 hrs
    		[PMID: 26376355]
    HCT-116 IC50
    1.26 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    		[PMID: 31991336]
    HCT-116 IC50
    1.27 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36153841]
    HCT-116 IC50
    1.28 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    		[PMID: 25874326]
    HCT-116 IC50
    1.31 μM
    Compound: SAHA
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
    		[PMID: 35984756]
    HCT-116 IC50
    1.31 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
    		[PMID: 28213282]
    HCT-116 IC50
    1.39 μM
    Compound: Vorinostat
    Cytotoxicity against human HCT116 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    		[PMID: 23829483]
    HCT-116 IC50
    1.4 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    HCT-116 IC50
    1.4 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    		[PMID: 28835797]
    HCT-116 IC50
    1.47 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells measured after 72 hrs
    Antiproliferative activity against human HCT-116 cells measured after 72 hrs
    		[PMID: 35697181]
    HCT-116 IC50
    1.55 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    HCT-116 IC50
    1.8 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HCT-116 cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    HCT-116 IC50
    1.8 μM
    Compound: SAHA, 3
    Cytotoxicity against human HCT116 cells assessed as cell viability after 96 hrs by MTS reduction assay
    Cytotoxicity against human HCT116 cells assessed as cell viability after 96 hrs by MTS reduction assay
    		[PMID: 18348516]
    HCT-116 IC50
    1.81 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human HCT116 cells assessed as cell viability after 72 hrs by CCK8 assay
    		[PMID: 26211462]
    HCT-116 IC50
    1.81 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    		[PMID: 31413795]
    HCT-116 IC50
    1.85 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
    		[PMID: 33957387]
    HCT-116 IC50
    1.85 μM
    Compound: 2
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 28953386]
    HCT-116 IC50
    1.85 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 27541357]
    HCT-116 IC50
    1.9 μM
    Compound: 5; SAHA
    Antiproliferative activity against human HCT116 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    HCT-116 IC50
    1.9 μM
    Compound: 4
    Concentration required to inhibit the HCT116 cell growth by 50%.
    Concentration required to inhibit the HCT116 cell growth by 50%.
    		[PMID: 11831887]
    HCT-116 CC50
    1000 nM
    Compound: 1
    Antiproliferative activity against human P53 expressing HCT116 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human P53 expressing HCT116 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    HCT-116 IC50
    1000 nM
    Compound: 1, SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19410459]
    HCT-116 IC50
    1000 nM
    Compound: 1, SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue viability assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue viability assay
    		[PMID: 18809328]
    HCT-116 IC50
    1000 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human HCT116 cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human HCT116 cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    HCT-116 IC50
    11.8 nM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
    		[PMID: 32679451]
    HCT-116 IC50
    1450 nM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 24 hrs by MTT assay
    		[PMID: 27186676]
    HCT-116 IC50
    1488.6 nM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT116 cells measured after 48 hrs by sulforhodamine-B assay
    Antiproliferative activity against human HCT116 cells measured after 48 hrs by sulforhodamine-B assay
    		[PMID: 27886544]
    HCT-116 IC50
    1617.76 nM
    Compound: SAHA
    Cytotoxicity against human HCT-116 cells after 72 hrs by SRB assay
    Cytotoxicity against human HCT-116 cells after 72 hrs by SRB assay
    		[PMID: 30819618]
    HCT-116 EC50
    2 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells after 71 hrs by MTS assay
    Cytotoxicity against human HCT116 cells after 71 hrs by MTS assay
    		[PMID: 20392638]
    HCT-116 GI50
    2.03 μM
    Compound: 1, SAHA
    Growth inhibition of human HCT116 cells after 96 hrs by MTT assay
    Growth inhibition of human HCT116 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    HCT-116 IC50
    2.2 μM
    Compound: 4
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    HCT-116 IC50
    2.35 μM
    Compound: SAHA
    Anti-proliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    HCT-116 IC50
    2.41 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    		[PMID: 35043615]
    HCT-116 GI50
    2.5 μM
    Compound: Vorin
    Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
    		[PMID: 24900743]
    HCT-116 IC50
    2.59 μM
    Compound: SAHA
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 34043359]
    HCT-116 GI50
    2.69 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 19822426]
    HCT-116 IC50
    2.7 μM
    Compound: 1; SAHA
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    HCT-116 IC50
    2.8 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 24296013]
    HCT-116 IC50
    2.81 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    HCT-116 IC50
    2.81 μM
    Compound: SA, SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    HCT-116 IC50
    2.85 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human HCT116 cells after 96 hrs by celltiter 96 assay
    Antiproliferative activity against human HCT116 cells after 96 hrs by celltiter 96 assay
    		[PMID: 21634430]
    HCT-116 EC50
    3 μM
    Compound: Vorinostat
    Antiproliferative activity against human HCT116 cells measured after 72 hrs by WST1 assay
    Antiproliferative activity against human HCT116 cells measured after 72 hrs by WST1 assay
    		[PMID: 27597246]
    HCT-116 IC50
    3.07 μM
    Compound: 4; SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by CCK-8 assay
    		[PMID: 29670692]
    HCT-116 IC50
    3.1 μM
    Compound: 1; SAHA
    Cytotoxicity in human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity in human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28885834]
    HCT-116 IC50
    3.45 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by WST8 assay
    		[PMID: 25261927]
    HCT-116 IC50
    3.59 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 34656899]
    HCT-116 IC50
    3.7 μM
    Compound: SAHA
    Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
    Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
    		[PMID: 33744687]
    HCT-116 IC50
    3.7 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 25815139]
    HCT-116 IC50
    3.75 μM
    Compound: SAHA
    Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
    Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
    		[PMID: 33744687]
    HCT-116 IC50
    32.46 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		10.1039/C5MD00247H
    HCT-116 IC50
    4.2 μM
    Compound: 1; SAHA
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33668008]
    HCT-116 IC50
    4.23 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    HCT-116 IC50
    4.25 μM
    Compound: 1, SAHA
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    HCT-116 IC50
    4.25 μM
    Compound: 6, SAHA
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 25906087]
    HCT-116 GI50
    4.64 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26555243]
    HCT-116 IC50
    4.9 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 32151834]
    HCT-116 IC50
    4.95 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells by MTT assay
    Antiproliferative activity against human HCT116 cells by MTT assay
    		[PMID: 31546197]
    HCT-116 IC50
    4.97 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    HCT-116 IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
    		[PMID: 29100734]
    HCT-116 IC50
    5.06 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		10.1039/C5MD00247H
    HCT-116 IC50
    5.53 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 30108831]
    HCT-116 IC50
    5.53 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    		[PMID: 29288941]
    HCT-116 IC50
    5.53 μM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26555243]
    HCT-116 IC50
    5.66 μM
    Compound: SAHA
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 37116762]
    HCT-116 IC50
    561.32 nM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    		[PMID: 30115492]
    HCT-116 IC50
    6 μM
    Compound: 1, SAHA
    Inhibition of human HCT116 cell proliferation after 48 hrs by MTT assay
    Inhibition of human HCT116 cell proliferation after 48 hrs by MTT assay
    		[PMID: 23493449]
    HCT-116 IC50
    6.15 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    HCT-116 IC50
    720 nM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    HCT-116 GI50
    740 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human HCT116 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    HCT-116 GI50
    750 nM
    Compound: SAHA
    Growth inhibition of human HCT116 cells after 72 hrs by SRB assay
    Growth inhibition of human HCT116 cells after 72 hrs by SRB assay
    		[PMID: 20884208]
    HCT-116 IC50
    882.5 nM
    Compound: SAHA
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    HCT-116 IC50
    895 nM
    Compound: 1; SAHA
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    		[PMID: 32679451]
    HCT-116 IC50
    9.6 μM
    Compound: SAHA
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    		[PMID: 29348808]
    HCT-15 GI50
    0.82 μM
    Compound: 1, SAHA
    Growth inhibition of HCT15 cells by SRB assay
    Growth inhibition of HCT15 cells by SRB assay
    		[PMID: 17477518]
    HCT-15 GI50
    0.82 μM
    Compound: 2, SAHA
    Antiproliferative activity against human HCT15 cells by SRB assay
    Antiproliferative activity against human HCT15 cells by SRB assay
    		[PMID: 16723227]
    HCT-15 GI50
    0.95 μM
    Compound: SAHA
    Growth inhibition of human HCT15 cells after 21 hrs by MTT assay
    Growth inhibition of human HCT15 cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    HCT-15 GI50
    2.49 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    HCT-15 GI50
    2.49 μM
    Compound: 2, SAHA
    Growth inhibition of human HCT15 cells by SRB assay
    Growth inhibition of human HCT15 cells by SRB assay
    		[PMID: 17904843]
    HCT-15 GI50
    2.49 μM
    Compound: SAHA
    Growth inhibition of human HCT15 cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human HCT15 cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    HCT-15 GI50
    2.49 μM
    Compound: SAHA
    Growth inhibition of human HCT15 cells after 5 days by sulforhodamine B assay
    Growth inhibition of human HCT15 cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    HCT-15 GI50
    2.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HCT15 cells after 72 hrs by MTS assay
    Growth inhibition of human HCT15 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    HCT-8 IC50
    0.35 μM
    Compound: 5; SAHA
    Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    HEK293 IC50
    > 30 μM
    Compound: SAHA
    Inhibition of recombinant human ERG expressed in HEK293 cells at -80 mV holding potential measured for 9 mins by Qpatch clamp method
    Inhibition of recombinant human ERG expressed in HEK293 cells at -80 mV holding potential measured for 9 mins by Qpatch clamp method
    		[PMID: 28947154]
    HEK293 IC50
    0.01 μM
    Compound: SAHA
    Inhibition of recombinant human GST-fused HDAC1 expressed in HEK293 cells Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    Inhibition of recombinant human GST-fused HDAC1 expressed in HEK293 cells Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    		[PMID: 30245394]
    HEK293 IC50
    0.013 μM
    Compound: 2, SAHA
    Inhibition of human recombinant HDAC1 expressed in human HEK293 cells using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
    Inhibition of human recombinant HDAC1 expressed in human HEK293 cells using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
    		10.1039/C2MD00317A
    HEK293 IC50
    0.016 μM
    Compound: SAHA
    Inhibition of full length human N-terminal FLAG-tagged HDAC6 (1 to 1215 residues) expressed in HEK293 cells preincubated for 15 mins followed by acetyl-Gly-Ala-[acetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
    Inhibition of full length human N-terminal FLAG-tagged HDAC6 (1 to 1215 residues) expressed in HEK293 cells preincubated for 15 mins followed by acetyl-Gly-Ala-[acetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
    		[PMID: 30613344]
    HEK293 IC50
    0.122 μM
    Compound: SAHA
    Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
    Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
    		[PMID: 31414801]
    HEK293 IC50
    0.241 μM
    Compound: SAHA
    Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
    Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
    		[PMID: 31414801]
    HEK293 IC50
    0.669 μM
    Compound: SAHA
    Inhibition of full length human N-terminal FLAG-tagged HDAC8 (1 to 377 residues) expressed in HEK293 cells preincubated for 15 mins followed by Boc-[trifluoroacetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
    Inhibition of full length human N-terminal FLAG-tagged HDAC8 (1 to 377 residues) expressed in HEK293 cells preincubated for 15 mins followed by Boc-[trifluoroacetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
    		[PMID: 30613344]
    HEK293 GI50
    13 μM
    Compound: 1, SAHA
    Growth inhibition of human HEK293 cells after 72 hrs by XTT assay
    Growth inhibition of human HEK293 cells after 72 hrs by XTT assay
    		[PMID: 24900500]
    HEK293 CC50
    2.3 μM
    Compound: Vorinostat
    Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
    		[PMID: 30973727]
    HEK293 GI50
    3.38 μM
    Compound: 1, SAHA
    Cytotoxicity against HEK293 cells assessed as growth inhibition after 96 hrs by MTT assay
    Cytotoxicity against HEK293 cells assessed as growth inhibition after 96 hrs by MTT assay
    		[PMID: 26814680]
    HEK293 IC50
    5170 nM
    Compound: SAHA
    Cytotoxicity against HEK293 cells after 48 hrs by resazurin dye based assay
    Cytotoxicity against HEK293 cells after 48 hrs by resazurin dye based assay
    		[PMID: 30245402]
    HEK-293T IC50
    4.5 μM
    Compound: Vorinostat
    Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
    Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
    		[PMID: 35175762]
    HEK-293T IC50
    8.221 μM
    Compound: SAHA
    Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    HEL IC50
    0.02 μM
    Compound: SAHA
    Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    HEL IC50
    0.15 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    HEL IC50
    0.19 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 72 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    HEL IC50
    0.21 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 28336407]
    HEL IC50
    0.25 μM
    Compound: Vorinostat
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 28371677]
    HEL IC50
    0.3 μM
    Compound: 3; SAHA
    Synergistic antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
    Synergistic antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
    		[PMID: 30901208]
    HEL IC50
    0.49 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    HEL IC50
    0.49 μM
    Compound: SA, SAHA
    Antiproliferative activity against HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against HEL cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    HEL IC50
    0.52 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    HEL IC50
    0.65 μM
    Compound: 1
    Antiproliferative activity against HEL cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against HEL cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    HEL IC50
    0.65 μM
    Compound: 3; SAHA
    Antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 30901208]
    HEL GI50
    0.76 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human HEL cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    		[PMID: 25800646]
    HEL IC50
    0.79 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 29500131]
    HEL IC50
    0.86 μM
    Compound: 2; SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
    		[PMID: 29940115]
    HEL IC50
    0.89 μM
    Compound: SAHA
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    HEL IC50
    1.27 μM
    Compound: SAHA
    Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    HEL IC50
    1.74 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    HEL IC50
    2.42 μM
    Compound: 1, SAHA
    Cytotoxicity against HEL cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against HEL cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    HEL IC50
    2.42 μM
    Compound: 6, SAHA
    Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 25906087]
    HEL 92.1.7 IC50
    0.49 μM
    Compound: 4
    Antiproliferative activity against human HEL 92.1.7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HEL 92.1.7 cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    HEL 92.1.7 IC50
    0.49 μM
    Compound: 2
    Antiproliferative activity against human HEL 92.1.7 cells after 36 hrs by PrestoBlue dye based assay
    Antiproliferative activity against human HEL 92.1.7 cells after 36 hrs by PrestoBlue dye based assay
    		[PMID: 28953386]
    HEL 92.1.7 IC50
    0.49 μM
    Compound: 1; SAHA
    Antiproliferative activity against HEL 92.1.7 cells harboring JAK2 V617F mutant after 36 hrs by PrestoBlue dye based assay
    Antiproliferative activity against HEL 92.1.7 cells harboring JAK2 V617F mutant after 36 hrs by PrestoBlue dye based assay
    		[PMID: 27541357]
    HeLa EC50
    0.0217 μM
    Compound: 1; SAHA; vorinostat
    Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA
    Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA
    		[PMID: 26611919]
    HeLa IC50
    0.053 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assay
    Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assay
    		[PMID: 23820574]
    HeLa IC50
    0.055 μM
    Compound: 1, SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence-based assay
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence-based assay
    		[PMID: 26814680]
    HeLa IC50
    0.063 μM
    Compound: 2, SAHA
    Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate preincubated for 4 hrs before substrate addition measured after 3 hrs by fluorescence assay
    Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate preincubated for 4 hrs before substrate addition measured after 3 hrs by fluorescence assay
    		10.1039/C2MD00317A
    HeLa IC50
    0.076 μM
    Compound: SAHA
    Inhibition of HDAC6 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    Inhibition of HDAC6 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    		[PMID: 26555243]
    HeLa IC50
    0.079 μM
    Compound: 2, SAHA
    Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
    		10.1039/C2MD00317A
    HeLa IC50
    0.079 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extracts using Fluor de Lys as substrate by fluorescence assay
    Inhibition of HDAC in human HeLa cell extracts using Fluor de Lys as substrate by fluorescence assay
    		[PMID: 22877635]
    HeLa IC50
    0.079 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cells by fluorescent activity assay
    Inhibition of HDAC in human HeLa cells by fluorescent activity assay
    		[PMID: 21420859]
    HeLa IC50
    0.079 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extract assessed as fluorophore release by fluorescence spectrophotometry
    Inhibition of HDAC in human HeLa cell extract assessed as fluorophore release by fluorescence spectrophotometry
    		[PMID: 21978679]
    HeLa IC50
    0.09 μM
    Compound: SAHA, Vorinostat
    Inhibition of human HDAC in HeLa cells after 30 mins by Fluor de Lys fluorescence assay
    Inhibition of human HDAC in HeLa cells after 30 mins by Fluor de Lys fluorescence assay
    		[PMID: 21889343]
    HeLa IC50
    0.1 μM
    Compound: SAHA
    Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysis
    Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysis
    		[PMID: 24742384]
    HeLa IC50
    0.1 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cells extracts after 60 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cells extracts after 60 mins by fluorescence assay
    		[PMID: 20576572]
    HeLa IC50
    0.102 μM
    Compound: vorinostat
    Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 26629860]
    HeLa IC50
    0.102 μM
    Compound: SAHA
    Inhibition of HDAC in human Hela cell nuclear extract after 15 mins
    Inhibition of HDAC in human Hela cell nuclear extract after 15 mins
    		[PMID: 23644210]
    HeLa IC50
    0.106 μM
    Compound: Vorinostat, SAHA, Zolinza
    Inhibition of full length FLAG-tagged recombinant HDAC3 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
    Inhibition of full length FLAG-tagged recombinant HDAC3 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
    		[PMID: 23964961]
    HeLa IC50
    0.107 μM
    Compound: 1, SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    		[PMID: 21476600]
    HeLa IC50
    0.11 μM
    Compound: 6, SAHA
    Inhibition of HDAC1/HDAC2 in human HeLa cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of HDAC1/HDAC2 in human HeLa cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    HeLa IC50
    0.11 μM
    Compound: 1, SAHA
    Inhibition of HDAC in HeLa cells by fluorescent activity assay
    Inhibition of HDAC in HeLa cells by fluorescent activity assay
    		[PMID: 17477518]
    HeLa IC50
    0.11 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine side chain of histone as substrate measured after 30 mins by fluorometric assay
    Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine side chain of histone as substrate measured after 30 mins by fluorometric assay
    		[PMID: 28011426]
    HeLa IC50
    0.11 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading flourimeter analysis
    Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading flourimeter analysis
    		[PMID: 25811792]
    HeLa IC50
    0.11 μM
    Compound: SAHA, Zolinza
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by UV-vis spectrophotometer analysis
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by UV-vis spectrophotometer analysis
    		[PMID: 26100440]
    HeLa IC50
    0.11 μM
    Compound: SAHA
    Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis
    Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis
    		[PMID: 23510562]
    HeLa IC50
    0.119 μM
    Compound: Vorinostat, SAHA, Zolinza
    Inhibition of full length FLAG-tagged recombinant HDAC1 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
    Inhibition of full length FLAG-tagged recombinant HDAC1 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
    		[PMID: 23964961]
    HeLa IC50
    0.12 μM
    Compound: SAHA
    Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis
    Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis
    		[PMID: 26629857]
    HeLa IC50
    0.122 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cells using Fluor de Lys as substrate by fluorescence assay
    Inhibition of HDAC in human HeLa cells using Fluor de Lys as substrate by fluorescence assay
    		[PMID: 23639537]
    HeLa IC50
    0.13 μM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cell extract using fluor de Lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC in human HeLa cell extract using fluor de Lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 23792316]
    HeLa IC50
    0.13 μM
    Compound: 1, SAHA
    Inhibition of HDAC1/2 in human HeLa cell extracts using acetylated histone peptide as substrate after 30 mins
    Inhibition of HDAC1/2 in human HeLa cell extracts using acetylated histone peptide as substrate after 30 mins
    		[PMID: 24525003]
    HeLa IC50
    0.14 μM
    Compound: SAHA
    Inhibition of HDAC1/HDAC2 isolated from human HeLa cells incubated for 30 mins by Color de Lys assay
    Inhibition of HDAC1/HDAC2 isolated from human HeLa cells incubated for 30 mins by Color de Lys assay
    		10.1039/C4MD00203B
    HeLa IC50
    0.147 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cytosolic extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cytosolic extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    		[PMID: 30245394]
    HeLa IC50
    0.16 μM
    Compound: SAHA
    Inhibition of HDAC6 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    Inhibition of HDAC6 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    HeLa IC50
    0.16 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
    		[PMID: 30879863]
    HeLa IC50
    0.168 μM
    Compound: 3; SAHA
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
    		[PMID: 30901208]
    HeLa IC50
    0.17 μM
    Compound: 2
    Inhibition of HDAC in human HeLa cells nuclear extracts by fluorometric assay
    Inhibition of HDAC in human HeLa cells nuclear extracts by fluorometric assay
    		[PMID: 23116147]
    HeLa IC50
    0.18 μM
    Compound: SAHA
    Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    HeLa IC50
    0.19 μM
    Compound: 1, SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 23493449]
    HeLa IC50
    0.19 μM
    Compound: SAHA
    Inhibition of HDAC1 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    Inhibition of HDAC1 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    		[PMID: 26555243]
    HeLa IC50
    0.193 μM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cells nuclear extracts using acetylated histone peptide as substrate after 30 mins by Color de Lys assay
    Inhibition of HDAC1/2 in human HeLa cells nuclear extracts using acetylated histone peptide as substrate after 30 mins by Color de Lys assay
    		[PMID: 26216016]
    HeLa IC50
    0.195 μM
    Compound: 1, SAHA, Vorinostat
    Inhibition of HDAC6 in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    Inhibition of HDAC6 in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    		[PMID: 21476600]
    HeLa IC50
    0.231 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa nuclear extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    Inhibition of HDAC in human HeLa nuclear extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
    		[PMID: 30245394]
    HeLa IC50
    0.26 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine as substrate after 30 mins by spectrophotometric analysis
    Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine as substrate after 30 mins by spectrophotometric analysis
    		[PMID: 24702857]
    HeLa IC50
    0.28 μM
    Compound: 2, (SAHA, vorinostat)
    Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetry
    Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetry
    		[PMID: 19419205]
    HeLa IC50
    0.33 μM
    Compound: SAHA
    Inhibition of HDAC8 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    Inhibition of HDAC8 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    		[PMID: 26555243]
    HeLa IC50
    0.35 μM
    Compound: SAHA
    Inhibition of class 1 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    Inhibition of class 1 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    		[PMID: 32267687]
    HeLa IC50
    0.48 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    HeLa IC50
    0.48 μM
    Compound: 1, SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorimetric analysis
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorimetric analysis
    		[PMID: 24766560]
    HeLa IC50
    0.56 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
    		[PMID: 26555243]
    HeLa IC50
    0.6 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
    Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
    		10.1039/C4MD00350K
    HeLa IC50
    0.7 μM
    Compound: SAHA
    Inhibition of HDAC from human HeLa cells by fluorogenic enzyme assay
    Inhibition of HDAC from human HeLa cells by fluorogenic enzyme assay
    		[PMID: 19457659]
    HeLa IC50
    0.72 μM
    Compound: SAHA
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    		[PMID: 24702857]
    HeLa IC50
    0.98 μM
    Compound: Zolinza, SAHA
    Inhibition of HDAC derived from human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorimetry
    Inhibition of HDAC derived from human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorimetry
    		[PMID: 22698782]
    HeLa IC50
    1.1 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay
    		[PMID: 20036560]
    HeLa IC50
    1.17 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    HeLa IC50
    1.41 μM
    Compound: SAHA
    Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    HeLa IC50
    1.5 μM
    Compound: 2a
    Cytotoxicity against human HeLa cells overexpressing HDAC by resazurin dye reduction assay
    Cytotoxicity against human HeLa cells overexpressing HDAC by resazurin dye reduction assay
    		[PMID: 21080629]
    HeLa IC50
    1.72 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 28336407]
    HeLa IC50
    1.84 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 29500131]
    HeLa IC50
    1.9 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    HeLa IC50
    107.8 nM
    Compound: 1, SAHA
    Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay
    Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 26122774]
    HeLa IC50
    11 nM
    Compound: Vorinostat
    Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after 60 mins by fluorescence analysis
    Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after 60 mins by fluorescence analysis
    		[PMID: 27597246]
    HeLa IC50
    11.5 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 27186676]
    HeLa IC50
    12 nM
    Compound: Vorinostat
    Inhibition of human HDAC in HeLa cell nuclear extract by fluorometric assay using Fluor de Lys substrate
    Inhibition of human HDAC in HeLa cell nuclear extract by fluorometric assay using Fluor de Lys substrate
    		[PMID: 26475519]
    HeLa IC50
    12.28 μM
    Compound: 1, SAHA
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    HeLa IC50
    12.28 μM
    Compound: 6, SAHA
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 25906087]
    HeLa IC50
    120.06 nM
    Compound: 1; SAHA
    Inhibition of HDAC activity in human HeLa cell nuclear extract using fluorometric substrate measured after 30 mins by fluorescence assay
    Inhibition of HDAC activity in human HeLa cell nuclear extract using fluorometric substrate measured after 30 mins by fluorescence assay
    		[PMID: 27886544]
    HeLa IC50
    121 nM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    		[PMID: 32267687]
    HeLa IC50
    131.26 nM
    Compound: 1; SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Lys(Ac)-pNA as substrate after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Lys(Ac)-pNA as substrate after 30 mins by fluorescence assay
    		[PMID: 28395150]
    HeLa IC50
    135 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extracts assessed as inhibition of substrate deacetylation using Boc-Lys (acetyl)-AMC as substrate by fluorescence based assay
    Inhibition of HDAC in human HeLa cell extracts assessed as inhibition of substrate deacetylation using Boc-Lys (acetyl)-AMC as substrate by fluorescence based assay
    		[PMID: 32247729]
    HeLa EC50
    14.2 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by XTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by XTT assay
    		[PMID: 21548582]
    HeLa IC50
    141 nM
    Compound: 1, SAHA
    Inhibition of HDAC in human HeLa cell nuclear extracts using Fluor de Lys as substrate by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extracts using Fluor de Lys as substrate by fluorescence assay
    		[PMID: 24119555]
    HeLa IC50
    144.8 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell extract using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell extract using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 25462271]
    HeLa GI50
    1460 nM
    Compound: SAHA
    Growth inhibition of human HeLa cells after 72 hrs by SRB assay
    Growth inhibition of human HeLa cells after 72 hrs by SRB assay
    		[PMID: 20884208]
    HeLa IC50
    147 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    HeLa IC50
    15 nM
    Compound: Vorinostat
    Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assay
    Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assay
    		[PMID: 26741358]
    HeLa IC50
    154.8 nM
    Compound: SAHA
    Inhibition of Class 1 histone deacetylase isolated from human HeLa cell nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay
    Inhibition of Class 1 histone deacetylase isolated from human HeLa cell nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 26349626]
    HeLa IC50
    159 nM
    Compound: Vorinostat
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method
    		[PMID: 28371677]
    HeLa IC50
    160.8 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extracts using (Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extracts using (Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 28336407]
    HeLa IC50
    161 nM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cell nuclear extracts preincubated for 5 mins followed by substrate addition measured after 0.5 hrs by Color de Lys assay
    Inhibition of HDAC1/2 in human HeLa cell nuclear extracts preincubated for 5 mins followed by substrate addition measured after 0.5 hrs by Color de Lys assay
    		[PMID: 26149591]
    HeLa IC50
    176.6 μM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate incubated for 2 hrs prior to substrate addition measured after 30 mins by fluorescence assay
    Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate incubated for 2 hrs prior to substrate addition measured after 30 mins by fluorescence assay
    		[PMID: 26386821]
    HeLa IC50
    18 nM
    Compound: 2, SAHA
    Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    		[PMID: 21984958]
    HeLa IC50
    18.9 μM
    Compound: SAHA
    Inhibition of class 2 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    Inhibition of class 2 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
    		[PMID: 32267687]
    HeLa IC50
    1860 nM
    Compound: SAHA
    Inhibition of HDAC8 from human HeLa cells nuclear extract by cell free fluorimetric assay
    Inhibition of HDAC8 from human HeLa cells nuclear extract by cell free fluorimetric assay
    		[PMID: 19093884]
    HeLa GI50
    19.21 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 28629630]
    HeLa IC50
    196 nM
    Compound: SAHA
    Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay
    Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay
    		[PMID: 20167479]
    HeLa IC50
    1989 nM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    		[PMID: 23622981]
    HeLa IC50
    1989 nM
    Compound: SAHA
    Inhibition of HDAC8 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC8 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 22260166]
    HeLa IC50
    2.04 μM
    Compound: SAHA
    Anticancer activity against human HeLa cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human HeLa cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    HeLa IC50
    2.06 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    HeLa IC50
    2.06 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    HeLa IC50
    2.12 μM
    Compound: SAHA
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    HeLa IC50
    2.2 μM
    Compound: 6, SAHA
    Cytotoxicity against human HeLa cells after 72 hrs by alamar-blue cell viability assay
    Cytotoxicity against human HeLa cells after 72 hrs by alamar-blue cell viability assay
    		[PMID: 19301902]
    HeLa IC50
    2.41 μM
    Compound: SAHA
    Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    		[PMID: 31991336]
    HeLa GI50
    2.5 μM
    Compound: 1, SAHA
    Growth inhibition of human HeLa cells after 72 hrs by XTT assay
    Growth inhibition of human HeLa cells after 72 hrs by XTT assay
    		[PMID: 24900500]
    HeLa IC50
    2.59 μM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cell nuclear extracts using Color de LysTM after 30 mins
    Inhibition of HDAC in human HeLa cell nuclear extracts using Color de LysTM after 30 mins
    		[PMID: 24095016]
    HeLa IC50
    2.6 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    HeLa IC50
    2.6 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs
    Antiproliferative activity against human HeLa cells after 48 hrs
    		[PMID: 24262004]
    HeLa IC50
    2.65 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 33021789]
    HeLa IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    		[PMID: 34624191]
    HeLa GI50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    		[PMID: 34500130]
    HeLa IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    		[PMID: 24296013]
    HeLa IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay
    Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    HeLa IC50
    2.8 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assay
    Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assay
    		[PMID: 23707260]
    HeLa CC50
    2.8 μM
    Compound: SAHA
    Cytotoxicity against human HeLa cells assessed as cell death incubated for 20 hrs measured by DNS assay
    Cytotoxicity against human HeLa cells assessed as cell death incubated for 20 hrs measured by DNS assay
    		[PMID: 34006099]
    HeLa IC50
    2.85 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    HeLa IC50
    2.9 μM
    Compound: Vorinostat
    Antiproliferative activity against human HeLa cells by CCK8 assay
    Antiproliferative activity against human HeLa cells by CCK8 assay
    		[PMID: 30660827]
    HeLa IC50
    2000 nM
    Compound: 2, SAHA
    Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometry
    Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometry
    		[PMID: 21984958]
    HeLa IC50
    27 nM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    		[PMID: 23622981]
    HeLa IC50
    27 nM
    Compound: SAHA
    Inhibition of HDAC6 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC6 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 22260166]
    HeLa IC50
    3.1 μM
    Compound: II, SAHA
    Antiproliferative activity against human HeLa cells after 4 hrs by WST-1 assay
    Antiproliferative activity against human HeLa cells after 4 hrs by WST-1 assay
    		[PMID: 18672316]
    HeLa GI50
    3.2 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    HeLa GI50
    3.36 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 23601706]
    HeLa IC50
    3.55 μM
    Compound: Vorinostat
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 28371677]
    HeLa IC50
    3.7 μM
    Compound: SAHA
    Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
    		[PMID: 25899338]
    HeLa IC50
    3.823 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
    Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
    		[PMID: 34454126]
    HeLa IC50
    38 nM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    		[PMID: 23622981]
    HeLa IC50
    38 nM
    Compound: SAHA
    Inhibition of HDAC1 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC1 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 22260166]
    HeLa IC50
    4.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 35477142]
    HeLa IC50
    4.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    		[PMID: 35255412]
    HeLa IC50
    4.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
    		[PMID: 33261898]
    HeLa IC50
    4.61 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    HeLa IC50
    4.66 μM
    Compound: SAHA
    Antiproliferative activity against siRNA-induced BAX knock down human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against siRNA-induced BAX knock down human HeLa cells after 48 hrs by MTT assay
    		[PMID: 33021789]
    HeLa EC50
    4.7 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
    		[PMID: 21548582]
    HeLa EC50
    4.8 μM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cells assessed as induction of histone H3 hyperacetylation after 24 hrs
    Inhibition of HDAC in human HeLa cells assessed as induction of histone H3 hyperacetylation after 24 hrs
    		[PMID: 18558669]
    HeLa IC50
    41 nM
    Compound: 2, SAHA
    Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    		[PMID: 21984958]
    HeLa IC50
    41 nM
    Compound: 2, SAHA
    Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
    		[PMID: 21984958]
    HeLa IC50
    416 nM
    Compound: SAHA
    Inhibition of HDAC1/HDAC2 in human HeLa cell extract incubated for 5 mins prior to substrate addition measured after 30 mins by microtitre plate reader analysis
    Inhibition of HDAC1/HDAC2 in human HeLa cell extract incubated for 5 mins prior to substrate addition measured after 30 mins by microtitre plate reader analysis
    		[PMID: 25311567]
    HeLa EC50
    43 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 24 hrs by XTT assay
    Antiproliferative activity against human HeLa cells after 24 hrs by XTT assay
    		[PMID: 21548582]
    HeLa CC50
    460 nM
    Compound: 1
    Antiproliferative activity against human P53-deficient HeLa cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human P53-deficient HeLa cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    HeLa IC50
    460 nM
    Compound: 1, SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by celltiter-blue viability assay
    Antiproliferative activity against human HeLa cells after 72 hrs by celltiter-blue viability assay
    		[PMID: 18809328]
    HeLa IC50
    460 nM
    Compound: 1, vorinostat
    Antiproliferative activity against human HeLa cells by CellTiter-Blue cell viability assay
    Antiproliferative activity against human HeLa cells by CellTiter-Blue cell viability assay
    		[PMID: 18370373]
    HeLa IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 32151834]
    HeLa IC50
    5.21 μM
    Compound: 1; SAHA
    Cytotoxicity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    HeLa IC50
    5.45 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    HeLa IC50
    6.07 μM
    Compound: SAHA
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    HeLa IC50
    65 nM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
    		[PMID: 23622981]
    HeLa IC50
    65 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assay
    		[PMID: 19914074]
    HeLa IC50
    65 nM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
    		[PMID: 22260166]
    HeLa IC50
    65 nM
    Compound: SAHA
    Inhibition of HDAC1/2 from human HeLa cells nuclear extract by cell free fluorimetric assay
    Inhibition of HDAC1/2 from human HeLa cells nuclear extract by cell free fluorimetric assay
    		[PMID: 19093884]
    HeLa IC50
    65 nM
    Compound: SAHA
    Inhibition of human HDAC in HeLa cells by flour de lys assay
    Inhibition of human HDAC in HeLa cells by flour de lys assay
    		[PMID: 18397827]
    HeLa IC50
    67 nM
    Compound: SAHA, Vorinostat
    Inhibition of HDAC in human HeLa cells using Ac-Arg-Gly-Lys(Ac)-AMC as fluorescent substrate after 20 mins by fluorescence assay
    Inhibition of HDAC in human HeLa cells using Ac-Arg-Gly-Lys(Ac)-AMC as fluorescent substrate after 20 mins by fluorescence assay
    		[PMID: 21621883]
    HeLa IC50
    67 nM
    Compound: SAHA, Zolinza
    Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluorimetry
    Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluorimetry
    		[PMID: 22435669]
    HeLa IC50
    7.13 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		10.1039/C5MD00247H
    HeLa IC50
    711 nM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    HeLa IC50
    8.96 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		10.1039/C5MD00247H
    HeLa IC50
    80 nM
    Compound: SAHA
    Inhibition of human HDAC in HeLa cells by fluorescent activity assay
    Inhibition of human HDAC in HeLa cells by fluorescent activity assay
    		[PMID: 19223622]
    HeLa IC50
    85.5 nM
    Compound: SAHA
    Inhibition of HDAC6 from human HeLa cells nuclear extract by cell free fluorimetric assay
    Inhibition of HDAC6 from human HeLa cells nuclear extract by cell free fluorimetric assay
    		[PMID: 19093884]
    HeLa IC50
    86 nM
    Compound: SAHA
    Inhibition of HDAC in human Hela cell lysate using Fluor-de-Lys as substrate compound pretreated for 30 mins before substrate addition by fluorescence assay
    Inhibition of HDAC in human Hela cell lysate using Fluor-de-Lys as substrate compound pretreated for 30 mins before substrate addition by fluorescence assay
    		[PMID: 23089527]
    HeLa IC50
    87 nM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in human HeLa cells nuclear extract using fluor de Lys as substrate preincubated for 5 mins by fluorometric analysis
    Inhibition of HDAC in human HeLa cells nuclear extract using fluor de Lys as substrate preincubated for 5 mins by fluorometric analysis
    		[PMID: 21080647]
    HeLa IC50
    87 nM
    Compound: SAHA
    Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetric assay
    Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetric assay
    		[PMID: 20884208]
    HeLa IC50
    9.19 μM
    Compound: SAHA
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		10.1039/C5MD00247H
    HeLa IC50
    9.69 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    		[PMID: 24095016]
    HeLa IC50
    91 nM
    Compound: SAHA
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 30 min by microtiter plate reader analysis
    Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 30 min by microtiter plate reader analysis
    		[PMID: 26907204]
    HeLa IC50
    96.4 nM
    Compound: 1, SAHA
    Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
    		[PMID: 22439863]
    HeLa IC50
    98.35 μM
    Compound: 1; SAHA
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
    		[PMID: 31655430]
    HeLa S3 IC50
    0.02 μM
    Compound: SAHA
    Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    		[PMID: 28337317]
    HeLa S3 IC50
    0.033 μM
    Compound: SAHA
    Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    		[PMID: 28337317]
    HeLa S3 IC50
    0.033 μM
    Compound: SAHA
    Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    		[PMID: 28337317]
    HeLa S3 IC50
    0.096 μM
    Compound: SAHA
    Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
    		[PMID: 28337317]
    Hep 3B2 GI50
    > 410 nM
    Compound: Vorinostat
    Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    Hep 3B2 GI50
    0.69 μM
    Compound: 1, SAHA
    Growth inhibition of human Hep3B cells after 48 hrs by SRB assay
    Growth inhibition of human Hep3B cells after 48 hrs by SRB assay
    		[PMID: 22439863]
    Hep 3B2 GI50
    1.21 μM
    Compound: SAHA
    Antiproliferative activity against human Hep3B cells after 48 hrs by SRB assay
    Antiproliferative activity against human Hep3B cells after 48 hrs by SRB assay
    		[PMID: 21712146]
    Hep 3B2 IC50
    2.3 μM
    Compound: Vorinostat
    Cytotoxicity against human Hep3B cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human Hep3B cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    Hep 3B2 IC50
    2.44 μM
    Compound: SAHA
    Antiproliferative activity against human Hep3B2 cells after hrs by ATP content assay
    Antiproliferative activity against human Hep3B2 cells after hrs by ATP content assay
    		[PMID: 20143778]
    Hep 3B2 IC50
    2.6 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    Hep 3B2 IC50
    5.4 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23707260]
    Hep 3B2 IC50
    5.58 μM
    Compound: SAHA
    Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    Hepatocyte GI50
    > 500 μM
    Compound: SAHA
    Growth inhibition of human hepatocytes after 21 hrs by MTT assay
    Growth inhibition of human hepatocytes after 21 hrs by MTT assay
    		[PMID: 17662606]
    HepG2 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    HepG2 IC50
    > 50 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    HepG2 EC50
    > 50 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 24 hrs by XTT assay
    Antiproliferative activity against human HepG2 cells after 24 hrs by XTT assay
    		[PMID: 21548582]
    HepG2 IC50
    0.14 μM
    Compound: SAHA, Vorinostat
    Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells after 48 hrs
    Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells after 48 hrs
    		[PMID: 24904967]
    HepG2 IC50
    0.18 μg/mL
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HepG2 IC50
    0.18 μM
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HepG2 IC50
    0.41 μM
    Compound: 1
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    HepG2 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    HepG2 IC50
    0.85 μM
    Compound: SAHA
    Cytotoxicity against human Hep-G2 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
    Cytotoxicity against human Hep-G2 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
    		[PMID: 34185525]
    HepG2 IC50
    1.18 μM
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
    Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
    		[PMID: 35175762]
    HepG2 IC50
    1.27 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    HepG2 IC50
    1.43 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    		[PMID: 34237620]
    HepG2 IC50
    1.49 μM
    Compound: SAHA, Vorinostat
    Cytotoxicity against human HepG2 cells after 48 hrs
    Cytotoxicity against human HepG2 cells after 48 hrs
    		[PMID: 24904967]
    HepG2 IC50
    1.54 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    HepG2 IC50
    1.66 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after hrs by ATP content assay
    Antiproliferative activity against human HepG2 cells after hrs by ATP content assay
    		[PMID: 20143778]
    HepG2 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    HepG2 IC50
    10.52 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		10.1039/C5MD00247H
    HepG2 IC50
    10.77 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		10.1039/C5MD00247H
    HepG2 CC50
    12 μM
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
    		[PMID: 30973727]
    HepG2 EC50
    12.2 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 23820574]
    HepG2 IC50
    13 μM
    Compound: Vorinostat
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    		[PMID: 35608269]
    HepG2 IC50
    2 μM
    Compound: 5; SAHA
    Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    HepG2 IC50
    2.26 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    HepG2 IC50
    2.265 μM
    Compound: SAHA
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    HepG2 IC50
    2.4 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    HepG2 EC50
    2.5 μM
    Compound: suberoylanilide
    Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
    Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
    		[PMID: 20966043]
    HepG2 IC50
    2.57 μM
    Compound: Vorinostat
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    HepG2 IC50
    2.8 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    HepG2 IC50
    2.9 μM
    Compound: Vorinostat
    Antiproliferative activity against human HepG2 cells by CCK8 assay
    Antiproliferative activity against human HepG2 cells by CCK8 assay
    		[PMID: 30660827]
    HepG2 GI50
    21.96 μM
    Compound: Vorinostat
    Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
    		[PMID: 29500130]
    HepG2 IC50
    23.62 μM
    Compound: SAHA
    Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by CCK8 assay
    		[PMID: 26211462]
    HepG2 IC50
    3.2 ng/mL
    Compound: SAHA; 1
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 3 days by trypan blue assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 3 days by trypan blue assay
    		[PMID: 35586423]
    HepG2 IC50
    3.33 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 29396364]
    HepG2 IC50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    		[PMID: 34624191]
    HepG2 GI50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    		[PMID: 34500130]
    HepG2 GI50
    3.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
    Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 22435669]
    HepG2 EC50
    3.8 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by XTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by XTT assay
    		[PMID: 21548582]
    HepG2 IC50
    3385 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    		[PMID: 34454126]
    HepG2 EC50
    35.5 μM
    Compound: suberoylanilide
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    		[PMID: 20966043]
    HepG2 IC50
    4.1 μM
    Compound: 1; SAHA
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28885834]
    HepG2 IC50
    4.5 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 30455152]
    HepG2 IC50
    4.95 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells by MTT assay
    Antiproliferative activity against human HepG2 cells by MTT assay
    		[PMID: 31546197]
    HepG2 GI50
    4600 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human HepG2 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    HepG2 IC50
    5.75 μM
    Compound: 1; SAHA
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    HepG2 IC50
    5.9 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 31120744]
    HepG2 IC50
    5.94 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    HepG2 IC50
    514.5 nM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    HepG2 IC50
    6 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    HepG2 IC50
    6.26 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 30108831]
    HepG2 IC50
    6.26 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 29288941]
    HepG2 GI50
    63.48 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 19822426]
    HepG2 IC50
    7.19 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    HepG2 IC50
    7.6 μM
    Compound: SAHA
    Cytotoxicity against human HepG2-A16-CD81EGFP cells assessed as inhibition of cell growth incubated for 24 hrs followed by medium transfer and incubation in multimode plate for 48 hrs by CellTiterGlo reagent based luminescence assay
    Cytotoxicity against human HepG2-A16-CD81EGFP cells assessed as inhibition of cell growth incubated for 24 hrs followed by medium transfer and incubation in multimode plate for 48 hrs by CellTiterGlo reagent based luminescence assay
    		[PMID: 33360801]
    HepG2 EC50
    8.4 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells after 48 hrs by XTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by XTT assay
    		[PMID: 21548582]
    HepG2 IC50
    8.78 μM
    Compound: SAHA
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		10.1039/C5MD00247H
    HepG2 IC50
    9.06 μM
    Compound: I-1; SAHA
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    		[PMID: 35245830]
    HepG2 IC50
    9.1 μM
    Compound: SAHA
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    		[PMID: 29348808]
    HepG2 IC50
    9.3 μM
    Compound: SAHA
    Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
    Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
    		[PMID: 20143840]
    HET-1A IC50
    960 nM
    Compound: SAHA
    Antiproliferative activity against human HET-1A cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HET-1A cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    HGC-27 IC50
    0.35 μM
    Compound: 5; SAHA
    Antiproliferative activity against human HGC27 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HGC27 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    HGC-27 IC50
    5.4 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human HGC27 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HGC27 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23707260]
    HGC-27 IC50
    5.79 μM
    Compound: SAHA
    Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    HH IC50
    0.86 μM
    Compound: 1; SAHA
    Cytotoxicity against human HH cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HH cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    		[PMID: 33588178]
    HH EC50
    1.03 μM
    Compound: SAHA
    Cytotoxicity against human HH cells assessed as cell proliferation after 70 hrs by MTS assay
    Cytotoxicity against human HH cells assessed as cell proliferation after 70 hrs by MTS assay
    		[PMID: 25974739]
    HL-60 IC50
    > 200 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    HL-60 IC50
    > 3.78 mM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    		[PMID: 20171895]
    HL-60 GI50
    0.08 μM
    Compound: SAHA
    Cytotoxicity against human HL60 cells after 72 hrs by cell titre 96 aqueous cell proliferation assay
    Cytotoxicity against human HL60 cells after 72 hrs by cell titre 96 aqueous cell proliferation assay
    		[PMID: 26653328]
    HL-60 IC50
    0.18 μg/mL
    Compound: Vorinostat
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HL-60 IC50
    0.22 μM
    Compound: Vorinostat
    Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    		[PMID: 36351184]
    HL-60 IC50
    0.42 μM
    Compound: SAHA
    Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition after 72 hrs by trypan blue staining based cell counting assay
    Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition after 72 hrs by trypan blue staining based cell counting assay
    		[PMID: 31883490]
    HL-60 IC50
    0.48 μM
    Compound: 1; SAHA
    Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    		[PMID: 33588178]
    HL-60 IC50
    0.52 μM
    Compound: SAHA
    Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTT assay
    		[PMID: 31413795]
    HL-60 IC50
    0.54 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36153841]
    HL-60 GI50
    0.55 μM
    Compound: SAHA
    Antiproliferative activity against human HL60 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human HL60 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    		[PMID: 25800646]
    HL-60 IC50
    0.69 μM
    Compound: Vorinostat
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HL-60 GI50
    0.75 μM
    Compound: Vorinostat
    Growth inhibition of human HL60 cells after 72 hrs by CellTiter Glo assay
    Growth inhibition of human HL60 cells after 72 hrs by CellTiter Glo assay
    		[PMID: 25182565]
    HL-60 IC50
    0.9 μM
    Compound: SAHA
    Cytotoxicity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
    Cytotoxicity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
    		[PMID: 34185525]
    HL-60 IC50
    0.93 μM
    Compound: 1; SAHA
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 34656899]
    HL-60 GI50
    0.93 μM
    Compound: 1, SAHA
    Growth inhibition of human HL60 cells after 72 hrs by XTT assay
    Growth inhibition of human HL60 cells after 72 hrs by XTT assay
    		[PMID: 24900500]
    HL-60 IC50
    1 μM
    Compound: SAHA
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    HL-60 EC50
    1.2 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human HL60 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    HL-60 EC50
    1.3 μM
    Compound: SAHA
    Induction of ATRA-induced human HL60 cell differentiation pretreated for 1 hr followed by ATRA addition measured after 3 days by Wright-Giemsa staining based microscopic analysis
    Induction of ATRA-induced human HL60 cell differentiation pretreated for 1 hr followed by ATRA addition measured after 3 days by Wright-Giemsa staining based microscopic analysis
    		[PMID: 28549889]
    HL-60 IC50
    1.5 μM
    Compound: 2; SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HL60 cells after 48 hrs by CCK-8 assay
    		[PMID: 29940115]
    HL-60 IC50
    1.52 μM
    Compound: SAHA
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    		[PMID: 36272186]
    HL-60 GI50
    1.74 μM
    Compound: SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by SRB assay
    Antiproliferative activity against human HL60 cells after 48 hrs by SRB assay
    		[PMID: 27344487]
    HL-60 GI50
    1.74 μM
    Compound: SAHA; 1
    Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 29567459]
    HL-60 IC50
    1331 nM
    Compound: SAHA
    Antiproliferative activity against Ara-C resistant human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against Ara-C resistant human HL60 cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    HL-60 IC50
    3.04 μM
    Compound: SAHA
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    HL-60 IC50
    4.26 μM
    Compound: SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    HL-60 IC50
    4.26 μM
    Compound: SA, SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    HL-60 IC50
    570.5 nM
    Compound: SAHA
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    HL-60 IC50
    729 nM
    Compound: SAHA
    Growth inhibition of human HL60 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
    Growth inhibition of human HL60 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
    		10.1039/C3MD00285C
    HL-60 IC50
    76.5 μM
    Compound: Zolinza, SAHA
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    		[PMID: 22698782]
    HL-60(TB) GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HL-60(TB) cells after 72 hrs by MTS assay
    Growth inhibition of human HL-60(TB) cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    HMEC EC50
    > 10 μM
    Compound: SAHA
    Cytotoxicity against HMEC after 72 hrs by trypan blue exclusion assay
    Cytotoxicity against HMEC after 72 hrs by trypan blue exclusion assay
    		[PMID: 19093884]
    HMEC IC50
    1.3 μM
    Compound: SAHA
    Cytotoxicity against HMEC after 72 hrs by MTT assay
    Cytotoxicity against HMEC after 72 hrs by MTT assay
    		[PMID: 18642892]
    HMEC IC50
    10.7 μM
    Compound: Vorinostat
    Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    		[PMID: 36262394]
    HMEC GI50
    5.8 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human HMEC after 72 hrs by WST1 assay
    Cytotoxicity against human HMEC after 72 hrs by WST1 assay
    		[PMID: 24015327]
    HONE1 cell line IC50
    1.18 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HONE1 cells by MTT assay
    Cytotoxicity against human HONE1 cells by MTT assay
    		[PMID: 24766560]
    HOP-62 GI50
    1.6 μM
    Compound: SAHA
    Antiproliferative activity against human HOP62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human HOP62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    HOP-62 IC50
    2.91 μM
    Compound: SAHA
    Cytotoxicity against human HOP-62 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HOP-62 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 35858522]
    HOP-92 GI50
    2.9 μM
    Compound: SAHA
    Antiproliferative activity against human HOP92 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human HOP92 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    HOP-92 GI50
    4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HOP92 cells after 72 hrs by MTS assay
    Growth inhibition of human HOP92 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    Hs-578T GI50
    3.6 μM
    Compound: SAHA
    Antiproliferative activity against human Hs578T cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human Hs578T cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    Hs-578T GI50
    4.83 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human Hs578T cells after 48 hrs by SRB assay
    Cytotoxicity against human Hs578T cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    Hs-578T GI50
    5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human Hs 578T cells after 72 hrs by MTS assay
    Growth inhibition of human Hs 578T cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    Hs68 IC50
    4.6 μM
    Compound: SAHA
    Cytotoxicity against human HS68 cells after 72 hrs by MTT assay
    Cytotoxicity against human HS68 cells after 72 hrs by MTT assay
    		[PMID: 23570542]
    HSC-3 IC50
    0.71 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HSC3 cells by MTT assay
    Cytotoxicity against human HSC3 cells by MTT assay
    		[PMID: 24766560]
    HT-1080 GI50
    1.79 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human HT1080 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human HT1080 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    HT-1080 IC50
    2.54 μM
    Compound: SAHA
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    HT-1080 IC50
    3.56 μM
    Compound: SAHA
    Anticancer activity against human HT-1080 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human HT-1080 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    HT-1080 GI50
    4.87 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human HT1080 cells by MTT assay
    Growth inhibition of human HT1080 cells by MTT assay
    		[PMID: 23601706]
    HT-29 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
    Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    HT-29 IC50
    0.56 μM
    Compound: SAHA
    Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    HT-29 IC50
    0.72 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human HT-29 cells by MTT assay
    Cytotoxicity against human HT-29 cells by MTT assay
    		[PMID: 24766560]
    HT-29 GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human HT-29 cells after 72 hrs by MTS assay
    Growth inhibition of human HT-29 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    HT-29 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    HT-29 IC50
    1.51 μM
    Compound: SAHA
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    HT-29 IC50
    1.78 μM
    Compound: 4; SAHA
    Antiproliferative activity against human HT-29 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by CCK-8 assay
    		[PMID: 29670692]
    HT-29 EC50
    2 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human HT-29 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    HT-29 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against human HT-29 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HT-29 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    HT-29 IC50
    2.37 μM
    Compound: SAHA
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    HT-29 GI50
    2.88 μM
    Compound: 1, SAHA
    Growth inhibition of human HT-29 cells after 96 hrs by MTT assay
    Growth inhibition of human HT-29 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    Huh-7 EC50
    0.36 μM
    Compound: 5, SAHA
    Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by luciferase reporter gene assay
    Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by luciferase reporter gene assay
    		[PMID: 25490700]
    Huh-7 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human Huh-7 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human Huh-7 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    Huh-7 CC50
    0.64 μM
    Compound: Vorinostat
    Cytotoxicity against human HuH7 cells assessed as reduction in cell viability incubated for 3 days by MTT assay
    Cytotoxicity against human HuH7 cells assessed as reduction in cell viability incubated for 3 days by MTT assay
    		[PMID: 31201063]
    Huh-7 IC50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human HuH7 cells after 72 hrs by CellTiter blue-reagent based assay
    Antiproliferative activity against human HuH7 cells after 72 hrs by CellTiter blue-reagent based assay
    		[PMID: 30645113]
    Huh-7 CC50
    1.9 μM
    Compound: 5, SAHA
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell viability after 3 days by CellTiter 96 assay
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell viability after 3 days by CellTiter 96 assay
    		[PMID: 25490700]
    Huh-7 IC50
    1.95 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human HuH-7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human HuH-7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    Huh-7 IC50
    3.88 μM
    Compound: SAHA
    Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    Huh-7 IC50
    4.3 μM
    Compound: 5; SAHA
    Antiproliferative activity against human HuH7 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HuH7 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    Huh-7 IC50
    4.95 μM
    Compound: SAHA
    Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay
    		[PMID: 29288941]
    Huh-7 IC50
    5.1 μM
    Compound: SAHA
    Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
    		[PMID: 31120744]
    HuP-T3 IC50
    0.8 μM
    Compound: 1a, SAHA
    Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay
    Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay
    		[PMID: 20055418]
    HuP-T3 IC50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human HupT3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HupT3 cells after 72 hrs by MTT assay
    		[PMID: 18642892]
    HuP-T3 IC50
    0.8 μM
    Compound: SAHA
    Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay
    Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay
    		[PMID: 18494463]
    HuP-T3 IC50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human HUPT3 cells by MTT assay
    Antiproliferative activity against human HUPT3 cells by MTT assay
    		[PMID: 19419863]
    HuT78 IC50
    0.71 μM
    Compound: 1; SAHA
    Cytotoxicity against human HuT78 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HuT78 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    		[PMID: 33588178]
    HuT78 GI50
    2.1 μM
    Compound: Vorin
    Cytotoxicity against human HUT78 cells after 72 hrs by MTS assay
    Cytotoxicity against human HUT78 cells after 72 hrs by MTS assay
    		[PMID: 24900743]
    HuT78 EC50
    290 nM
    Compound: 1
    Pro-apoptotic activity in human HUT78 cells after 18 hrs by caspase-Glo 3/7 assay
    Pro-apoptotic activity in human HUT78 cells after 18 hrs by caspase-Glo 3/7 assay
    		[PMID: 30122227]
    HuT78 GI50
    295 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human HUT78 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human HUT78 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    HuT78 GI50
    3 μM
    Compound: 2, SAHA, Vorinostat
    Cytotoxicity against human HUT78 cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against human HUT78 cells after 72 hrs by MTS-PMS assay
    		[PMID: 24164245]
    HuT78 GI50
    300 nM
    Compound: SAHA
    Growth inhibition of human HUT78 cells after 72 hrs by SRB assay
    Growth inhibition of human HUT78 cells after 72 hrs by SRB assay
    		[PMID: 20884208]
    HUVEC IC50
    > 50 μM
    Compound: SAHA
    Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    		[PMID: 37079967]
    HUVEC IC50
    0.85 μM
    Compound: SAHA
    Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by fluorimetry
    Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by fluorimetry
    		[PMID: 32347094]
    HUVEC IC50
    2.72 μM
    Compound: SAHA
    Cytotoxicity against HUVEC cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against HUVEC cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 37116762]
    HUVEC IC50
    2.84 μM
    Compound: SAHA
    Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    HUVEC IC50
    3610 nM
    Compound: SAHA
    Antiproliferative activity against HUVEC cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against HUVEC cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    HUVEC GI50
    8.13 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of HUVEC by MTT assay
    Growth inhibition of HUVEC by MTT assay
    		[PMID: 23601706]
    HUVEC IC50
    8.58 μM
    Compound: SAHA
    Cytotoxicity against HUVEC cells incubated for 72 hrs by CCK-8 assay
    Cytotoxicity against HUVEC cells incubated for 72 hrs by CCK-8 assay
    		[PMID: 36182802]
    IGROV-1 GI50
    1.1 μM
    Compound: SAHA
    Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    IGROV-1 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human IGROV1 cells after 72 hrs by MTS assay
    Growth inhibition of human IGROV1 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against human IGROV1 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    Antiproliferative activity against human IGROV1 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    		[PMID: 26890116]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Growth inhibition of human IGROV1 cells after 72 hrs
    Growth inhibition of human IGROV1 cells after 72 hrs
    		[PMID: 26376355]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Growth inhibition of human IGROV1/Pt1 cells after 72 hrs
    Growth inhibition of human IGROV1/Pt1 cells after 72 hrs
    		[PMID: 26376355]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against human IGROV1 cells assessed as growth inhibition after 72 hrs
    Antiproliferative activity against human IGROV1 cells assessed as growth inhibition after 72 hrs
    		[PMID: 24742384]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against p53 defective cis-platinum-resistant human IGROV1/Pt1 cells assessed as growth inhibition after 72 hrs
    Antiproliferative activity against p53 defective cis-platinum-resistant human IGROV1/Pt1 cells assessed as growth inhibition after 72 hrs
    		[PMID: 24742384]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against human IGROV1 cells after 72 hrs
    Antiproliferative activity against human IGROV1 cells after 72 hrs
    		[PMID: 19084294]
    IGROV-1 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against cisplatin-resistant human IGROV1 cells after 72 hrs
    Antiproliferative activity against cisplatin-resistant human IGROV1 cells after 72 hrs
    		[PMID: 19084294]
    IMR-32 IC50
    0.62 μM
    Compound: Vorinostat
    Antiproliferative activity against human IMR32 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    Antiproliferative activity against human IMR32 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    		[PMID: 31391882]
    JeKo-1 IC50
    0.42 μM
    Compound: SAHA
    Antiproliferative activity against human JeKo1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Antiproliferative activity against human JeKo1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 26890114]
    JeKo-1 IC50
    3.5 μM
    Compound: SAHA
    Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    JeKo-1 IC50
    638.6 nM
    Compound: SAHA
    Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    Jurkat IC50
    > 10 μM
    Compound: 4, SAHA
    Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-TFA as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
    Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-TFA as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
    		[PMID: 24261862]
    Jurkat IC50
    > 30 μM
    Compound: 3; SAHA
    Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    Jurkat IC50
    0.04 μM
    Compound: 4, SAHA
    Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-Ac as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
    Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-Ac as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
    		[PMID: 24261862]
    Jurkat IC50
    0.1 μM
    Compound: 1; SAHA
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33668008]
    Jurkat IC50
    0.27 μM
    Compound: 3; SAHA
    Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 30901208]
    Jurkat IC50
    0.3 μM
    Compound: SAHA
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 35043615]
    Jurkat IC50
    0.35 μM
    Compound: SAHA
    Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    Jurkat IC50
    0.47 μM
    Compound: Vorinostat
    Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
    		[PMID: 36351184]
    Jurkat IC50
    0.59 μM
    Compound: 4
    Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    Jurkat IC50
    0.7 μM
    Compound: 1; SAHA
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 48 hrs MTT assay
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 48 hrs MTT assay
    		[PMID: 33668008]
    Jurkat EC50
    0.72 μM
    Compound: SAHA
    Growth inhibition of human Jurkat cells after 44 hrs by MTT assay
    Growth inhibition of human Jurkat cells after 44 hrs by MTT assay
    		[PMID: 28337317]
    Jurkat EC50
    0.87 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human Jurkat JA16 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human Jurkat JA16 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    Jurkat GI50
    0.9 μM
    Compound: Vorin
    Cytotoxicity against human Jurkat cells after 72 hrs by MTS assay
    Cytotoxicity against human Jurkat cells after 72 hrs by MTS assay
    		[PMID: 24900743]
    Jurkat GI50
    1.1 μM
    Compound: 1, SAHA
    Growth inhibition of human Jurkat cells after 72 hrs by XTT assay
    Growth inhibition of human Jurkat cells after 72 hrs by XTT assay
    		[PMID: 24900500]
    Jurkat IC50
    1.18 μM
    Compound: SAHA
    Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
    		[PMID: 29500131]
    Jurkat IC50
    1.49 μM
    Compound: SAHA
    Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 24304348]
    Jurkat IC50
    1.49 μM
    Compound: SAHA
    Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 23547652]
    Jurkat EC50
    1.66 μM
    Compound: SAHA
    Cytotoxicity against human Jurkat cells assessed as cell proliferation after 70 hrs by MTS assay
    Cytotoxicity against human Jurkat cells assessed as cell proliferation after 70 hrs by MTS assay
    		[PMID: 25974739]
    Jurkat IC50
    10 nM
    Compound: 5; SAHA
    Inhibition of HDAC1 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
    Inhibition of HDAC1 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
    		[PMID: 27177826]
    Jurkat EC50
    1600 nM
    Compound: Vorinostat
    Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by Steady-Glo luciferase assay
    Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by Steady-Glo luciferase assay
    		[PMID: 32676157]
    Jurkat IC50
    20 nM
    Compound: 5; SAHA
    Inhibition of HDAC3 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
    Inhibition of HDAC3 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
    		[PMID: 27177826]
    Jurkat IC50
    3.62 μM
    Compound: SAHA
    Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    		[PMID: 37079967]
    Jurkat IC50
    32 μM
    Compound: 1; SAHA
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 24 hrs MTT assay
    Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 24 hrs MTT assay
    		[PMID: 33668008]
    K562 IC50
    0.11 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    K562 IC50
    0.14 μM
    Compound: SAHA
    Inhibition of HDAC in human K562 cell extract using Fluor-de-Lys deacetylase as substrate preincubated for 45 mins measured after 15 mins by fluorescence assay
    Inhibition of HDAC in human K562 cell extract using Fluor-de-Lys deacetylase as substrate preincubated for 45 mins measured after 15 mins by fluorescence assay
    		[PMID: 24328302]
    K562 IC50
    0.17 μM
    Compound: 1; SAHA
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
    		[PMID: 27142751]
    K562 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    K562 ED50
    0.45791 μM
    Compound: 5; SAHA
    Potentiation of (-)-lomaiviticin A-induced cytotoxicity against human K562 cells assessed as (-)-lomaiviticin A ED50 at compound to (-)-lomaiviticin A ratio of 5000:1 after 48 hrs by cell titer-glo luminescence assay (Rvb = 0.23776 nM)
    Potentiation of (-)-lomaiviticin A-induced cytotoxicity against human K562 cells assessed as (-)-lomaiviticin A ED50 at compound to (-)-lomaiviticin A ratio of 5000:1 after 48 hrs by cell titer-glo luminescence assay (Rvb = 0.23776 nM)
    		[PMID: 27177826]
    K562 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human K562 cells after 72 hrs by MTS assay
    Growth inhibition of human K562 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    K562 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human K562 cells after 72 hrs by MTS assay
    Growth inhibition of human K562 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    K562 IC50
    0.52 μM
    Compound: 1
    Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    K562 GI50
    0.52 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    		[PMID: 25800646]
    K562 IC50
    0.56 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    K562 IC50
    0.64 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay
    Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 23792316]
    K562 IC50
    0.645 μM
    Compound: vorinostat
    Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
    		[PMID: 26629860]
    K562 IC50
    0.65 μM
    Compound: SAHA
    Cytotoxicity against human K562 cells after 72 hrs by CellTiter-Glo assay
    Cytotoxicity against human K562 cells after 72 hrs by CellTiter-Glo assay
    		[PMID: 30245394]
    K562 IC50
    0.67 μM
    Compound: 6, SAHA
    Cytotoxicity against human K562 cells after 72 hrs by alamar-blue cell viability assay
    Cytotoxicity against human K562 cells after 72 hrs by alamar-blue cell viability assay
    		[PMID: 19301902]
    K562 IC50
    0.68 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    K562 IC50
    0.68 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    K562 IC50
    0.75 μM
    Compound: 3, SAHA
    Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
    Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
    		[PMID: 18038969]
    K562 IC50
    0.9 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    		[PMID: 34624191]
    K562 GI50
    0.9 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    		[PMID: 34500130]
    K562 IC50
    0.98 μM
    Compound: SAHA
    Anti-proliferative activity against human K562 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    K562 IC50
    1 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by trypan blue dye exclusion method
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by trypan blue dye exclusion method
    		[PMID: 25221651]
    K562 IC50
    1.02 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    K562 IC50
    1.03 μM
    Compound: 3; SAHA
    Synergistic antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
    Synergistic antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
    		[PMID: 30901208]
    K562 IC50
    1.11 μM
    Compound: 3; SAHA
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 30901208]
    K562 IC50
    1.17 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    		[PMID: 36272186]
    K562 ED50
    1.24803 μM
    Compound: 5; SAHA
    Cytotoxicity against human K562 cells assessed as decrease in cell viability after 48 hrs by cell titer-glo luminescence assay
    Cytotoxicity against human K562 cells assessed as decrease in cell viability after 48 hrs by cell titer-glo luminescence assay
    		[PMID: 27177826]
    K562 IC50
    1.35 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells by MTT assay
    Antiproliferative activity against human K562 cells by MTT assay
    		[PMID: 33132117]
    K562 IC50
    1.35 μM
    Compound: Vorinostat
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    K562 IC50
    1.391 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 35926141]
    K562 IC50
    1.44 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    K562 IC50
    1.45 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
    		[PMID: 31413795]
    K562 IC50
    1.49 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 28336407]
    K562 IC50
    1.51 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells incubated for 24 hrs by CCK8 assay
    Antiproliferative activity against human K562 cells incubated for 24 hrs by CCK8 assay
    		[PMID: 32247729]
    K562 IC50
    1.52 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    K562 IC50
    1.61 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 25311567]
    K562 IC50
    1.91 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    K562 IC50
    1.91 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    		[PMID: 28419930]
    K562 IC50
    1.95 μM
    Compound: Vorinostat
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 28371677]
    K562 GI50
    1.97 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    K562 IC50
    10 μM
    Compound: 5; SAHA
    Antiproliferative activity against human K562 cells after 96 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    K562 IC50
    143 nM
    Compound: 24; SAHA
    Inhibition of HDAC in human K562 cell extracts using (QSY-7)-RGGRGLGK(Ac)-GGARRHRK(TAMRA)NH2 as substrate preincubated for 30 mins followed by addition of endoproteinase Lys-C and measured after 2 hrs by fluorescence assay
    Inhibition of HDAC in human K562 cell extracts using (QSY-7)-RGGRGLGK(Ac)-GGARRHRK(TAMRA)NH2 as substrate preincubated for 30 mins followed by addition of endoproteinase Lys-C and measured after 2 hrs by fluorescence assay
    		[PMID: 31536895]
    K562 IC50
    2 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    K562 EC50
    2.2 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human K562 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    K562 IC50
    2.24 μM
    Compound: 3; SAHA
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    K562 IC50
    2.9 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    K562 IC50
    3.24 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    K562 IC50
    3.24 μM
    Compound: SA, SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    K562 IC50
    3.32 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    K562 GI50
    3.66 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 28629630]
    K562 IC50
    3.77 μM
    Compound: 1, SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 24525003]
    K562 IC50
    3.88 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    K562 IC50
    3.89 μM
    Compound: SAHA
    Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    K562 IC50
    3.94 μM
    Compound: SAHA
    Cytotoxicity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26149591]
    K562 IC50
    4.95 μM
    Compound: SAHA
    Antiproliferative activity against human K562 cells by MTT assay
    Antiproliferative activity against human K562 cells by MTT assay
    		[PMID: 31546197]
    K562 IC50
    444 nM
    Compound: SAHA
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    K562 IC50
    7.7 μM
    Compound: 2; SAHA
    Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
    		[PMID: 29940115]
    K562/A02 IC50
    3.13 μM
    Compound: SAHA
    Antiproliferative activity against human K562/A02 cells overexpressing P-gp by MTT assay
    Antiproliferative activity against human K562/A02 cells overexpressing P-gp by MTT assay
    		[PMID: 33132117]
    Kasumi 1 IC50
    620 nM
    Compound: Vorinostat
    Cytotoxicity against human Kasumi 1 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human Kasumi 1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    KATO III stomach cancer cell line IC50
    0.25 μM
    Compound: 3; SAHA
    Antiproliferative activity against human KATO III stomach cancer cell line assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human KATO III stomach cancer cell line assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    KB IC50
    0.75 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human KB cells by MTT assay
    Cytotoxicity against human KB cells by MTT assay
    		[PMID: 24766560]
    KB IC50
    1.8 μM
    Compound: SAHA
    Cytotoxicity against human KB cells after 72 hrs by MTS assay
    Cytotoxicity against human KB cells after 72 hrs by MTS assay
    		[PMID: 25899338]
    KB-V1 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human vinblastine resistant KB-V1 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human vinblastine resistant KB-V1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    KB-V1 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human KB-V1 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human KB-V1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    KG-1 IC50
    0.07 μM
    Compound: SAHA
    Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    KG-1 IC50
    0.59 μM
    Compound: 1; SAHA
    Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    		[PMID: 33588178]
    KG-1 IC50
    0.64 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    KG-1 IC50
    0.68 μM
    Compound: 1, SAHA
    Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    KG-1 IC50
    0.68 μM
    Compound: 6, SAHA
    Cytotoxicity against human KG1 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human KG1 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 25906087]
    KG-1 IC50
    0.9 μM
    Compound: SAHA
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 26907204]
    KG-1 IC50
    1.11 μM
    Compound: SAHA
    Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    KG-1 IC50
    1.15 μM
    Compound: 1, SAHA
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 24525003]
    KG-1 IC50
    1.52 μM
    Compound: SAHA
    Antiproliferative activity against human KG1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    KG-1 IC50
    1.59 μM
    Compound: SAHA
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    KG-1 IC50
    1.59 μM
    Compound: SA, SAHA
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    KG-1 IC50
    1.59 μM
    Compound: SAHA
    Antiproliferative activity against human KG-1 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human KG-1 cells incubated for 72 hrs by MTT assay
    		[PMID: 32961382]
    KG-1 IC50
    2.75 μM
    Compound: SAHA
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    		[PMID: 26216016]
    KM12 GI50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human KM12 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human KM12 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    KM12 GI50
    1.88 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human KM12 cells after 48 hrs by SRB assay
    Cytotoxicity against human KM12 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    KM12 GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human KM12 cells after 72 hrs by MTS assay
    Growth inhibition of human KM12 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    KM3/BTZ IC50
    78.2 nM
    Compound: SAHA
    Antiproliferative activity against bortezomib resistant human KM3/BTZ cells in presence of bortezomib incubated for 48 hrs by MTT assay
    Antiproliferative activity against bortezomib resistant human KM3/BTZ cells in presence of bortezomib incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    KM3/BTZ IC50
    860 nM
    Compound: SAHA
    Antiproliferative activity against bortezomib resistant human KM3/BTZ cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against bortezomib resistant human KM3/BTZ cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    KM-H2 IC50
    1.54 μM
    Compound: SAHA
    Antiproliferative activity against human KM-H2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human KM-H2 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    KMS-12-BM IC50
    0.94 μM
    Compound: 1; SAHA
    Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo assay
    		[PMID: 27541357]
    KMS-12-BM EC50
    0.94 μM
    Compound: 3; SAHA
    Antiproliferative activity against human KMS-12-BM cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    Antiproliferative activity against human KMS-12-BM cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 31627059]
    KMS-12-BM IC50
    0.94 μM
    Compound: 2
    Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo luminescent assay
    Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo luminescent assay
    		[PMID: 28953386]
    KMS-12-BM IC50
    0.94 μM
    Compound: 4
    Antiproliferative activity against human KMS-12-BM cells after 72 hrs by MTT assay
    Antiproliferative activity against human KMS-12-BM cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    KYSE-510 IC50
    0.59 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin resistant human KYSE-510 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin resistant human KYSE-510 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    KYSE-510 IC50
    0.7 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin sensitive human KYSE-510 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin sensitive human KYSE-510 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    KYSE-510 IC50
    4.62 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin sensitive human KYSE-510 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin sensitive human KYSE-510 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    KYSE-510 IC50
    4.66 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin resistant human KYSE-510 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin resistant human KYSE-510 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    KYSE-520 cell line IC50
    2.81 μM
    Compound: SAHA
    Antiproliferative activity against human KYSE520 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human KYSE520 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    L02 IC50
    > 10 μM
    Compound: SAHA
    Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    L02 IC50
    > 50 μM
    Compound: SAHA
    Cytotoxicity against human L02 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human L02 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    L02 IC50
    > 50000 nM
    Compound: SAHA
    Antiproliferative activity against human HL7702 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HL7702 cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    L02 IC50
    0.948 μM
    Compound: SAHA
    Antiproliferative activity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    L02 IC50
    1.35 μM
    Compound: SAHA
    Cytotoxicity against human HL7702 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human HL7702 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    L02 IC50
    27.4 μM
    Compound: SAHA
    Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 33021789]
    L02 IC50
    5.45 μM
    Compound: Vorinostat
    cytotoxicity against human HL-7702 cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
    cytotoxicity against human HL-7702 cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    L-428 IC50
    0.87 μM
    Compound: SAHA
    Antiproliferative activity against human L428 cells after 72 hrs by MTT assay
    Antiproliferative activity against human L428 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    L-428 IC50
    2.3 μM
    Compound: SAHA
    Antiproliferative activity against human L-428 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human L-428 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    Lewis lung carcinoma cell line IC50
    9.68 μM
    Compound: 4; SAHA
    Antiproliferative activity against mouse LLC cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against mouse LLC cells after 48 hrs by CCK-8 assay
    		[PMID: 29670692]
    LNCaP IC50
    0.69 μM
    Compound: SAHA
    Antiproliferative activity against human LNCAP cells incubated for 96 hrs by resazurin assay
    Antiproliferative activity against human LNCAP cells incubated for 96 hrs by resazurin assay
    		[PMID: 32435375]
    LNCaP IC50
    1 μM
    Compound: 5, SAHA
    Antiproliferative activity against human LNCap by MTT assay
    Antiproliferative activity against human LNCap by MTT assay
    		[PMID: 18166465]
    LNCaP IC50
    1.22 μM
    Compound: SAHA
    Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    LNCaP IC50
    1.8 μM
    Compound: SAHA
    Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 28131715]
    LNCaP IC50
    2.31 μM
    Compound: SAHA
    Cytotoxicity against androgen-dependent human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against androgen-dependent human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
    		[PMID: 24304348]
    LNCaP IC50
    2.31 μM
    Compound: SAHA
    Cytotoxicity against human LNCAP cells assessed as growth inhibition by MTS assay
    Cytotoxicity against human LNCAP cells assessed as growth inhibition by MTS assay
    		[PMID: 23547652]
    LNCaP IC50
    2.31 μM
    Compound: SAHA
    Inhibition of HDAC6 in human LNCAP cells assessed as tubulin acetylation by Western blot analysis
    Inhibition of HDAC6 in human LNCAP cells assessed as tubulin acetylation by Western blot analysis
    		[PMID: 25240614]
    LoVo GI50
    1700 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human LoVo cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human LoVo cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    LoVo IC50
    2.15 μM
    Compound: SAHA
    Antiproliferative activity against human LoVo cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human LoVo cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    LoVo IC50
    3.7 μM
    Compound: SAHA
    Antiproliferative activity against human LoVo cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    Antiproliferative activity against human LoVo cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    		[PMID: 26890116]
    LoVo IC50
    4.95 μM
    Compound: SAHA
    Antiproliferative activity against human LoVo cells by MTT assay
    Antiproliferative activity against human LoVo cells by MTT assay
    		[PMID: 31546197]
    LoVo IC50
    6.75 μM
    Compound: SAHA
    Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
    Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
    		[PMID: 30108831]
    LoVo IC50
    6.75 μM
    Compound: SAHA
    Antiproliferative activity against human LoVo cells assessed as cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human LoVo cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26555243]
    LOX IMVI GI50
    1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human LOXIMVI cells after 72 hrs by MTS assay
    Growth inhibition of human LOXIMVI cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    LOX IMVI GI50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human LOXIMVI cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human LOXIMVI cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    LOX IMVI GI50
    1.3 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    LOX IMVI GI50
    1.39 μM
    Compound: 1, SAHA
    Growth inhibition of LOX-IMVI cells by SRB assay
    Growth inhibition of LOX-IMVI cells by SRB assay
    		[PMID: 17477518]
    LOX IMVI GI50
    1.39 μM
    Compound: 2, SAHA
    Antiproliferative activity against human LOX-IMVI cells by SRB assay
    Antiproliferative activity against human LOX-IMVI cells by SRB assay
    		[PMID: 16723227]
    LOX IMVI GI50
    1.6 μM
    Compound: SAHA
    Growth inhibition of human LOX-IMVI cells after 21 hrs by MTT assay
    Growth inhibition of human LOX-IMVI cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    LP-1 IC50
    1.39 μM
    Compound: SAHA
    Antiproliferative activity against human LP-1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Antiproliferative activity against human LP-1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 26890114]
    M14 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human M14 cells after 72 hrs by MTS assay
    Growth inhibition of human M14 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    M14 GI50
    1.3 μM
    Compound: SAHA
    Antiproliferative activity against human M14 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human M14 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    Malme-3M GI50
    0.32 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MALME-3M cells after 72 hrs by MTS assay
    Growth inhibition of human MALME-3M cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    Malme-3M GI50
    0.37 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human MALME-3M cells after 48 hrs by SRB assay
    Cytotoxicity against human MALME-3M cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    MC-38 IC50
    1.26 μM
    Compound: SAHA
    Antiproliferative activity against mouse MC38 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against mouse MC38 cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    MC-38 GI50
    2.4 μM
    Compound: 7; SAHA
    Antiproliferative activity against mouse MC38 cells measured after 72 hrs by CCK8 assay
    Antiproliferative activity against mouse MC38 cells measured after 72 hrs by CCK8 assay
    		[PMID: 34783558]
    MC-38 GI50
    2.74 μM
    Compound: 3; SAHA
    Antiproliferative activity against mouse MC38 cells after 72 hrs by CCK-8 assay
    Antiproliferative activity against mouse MC38 cells after 72 hrs by CCK-8 assay
    		[PMID: 35390714]
    MCF-10A IC50
    > 50 μM
    Compound: 1; SAHA
    Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by SRB assay
    Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by SRB assay
    		[PMID: 32180916]
    MCF-10A IC50
    0.42 μM
    Compound: 6; SAHA
    Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MCF-10A IC50
    1.1 μM
    Compound: 6; SAHA
    Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MCF-10A IC50
    2.11 μM
    Compound: SAHA
    Antiproliferative activity against human MCF10A cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF10A cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    MCF-10A IC50
    28 μM
    Compound: SAHA
    Cytotoxicity against human MCF10A cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF10A cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    MCF-10A IC50
    31 μM
    Compound: 3, SAHA
    Cytotoxicity against human MCF10A cells after 96 hrs by MTA reduction assay
    Cytotoxicity against human MCF10A cells after 96 hrs by MTA reduction assay
    		[PMID: 23293738]
    MCF-10A GI50
    9.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MCF10A cells after 48 hrs by MTT assay
    Growth inhibition of human MCF10A cells after 48 hrs by MTT assay
    		[PMID: 22435669]
    MCF7 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
    		[PMID: 34116381]
    MCF7 IC50
    > 150 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    MCF7 IC50
    > 50 μM
    Compound: 1; SAHA
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33668008]
    MCF7 EC50
    0.01 μM
    Compound: 25a
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by SRB assay
    		[PMID: 34591488]
    MCF7 IC50
    0.16 μM
    Compound: 1
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
    		[PMID: 35238576]
    MCF7 IC50
    0.32 μM
    Compound: 6; SAHA
    Antiproliferative activity against human MCF7 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
    Antiproliferative activity against human MCF7 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
    		[PMID: 26613635]
    MCF7 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    MCF7 GI50
    0.45 μM
    Compound: 1, SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 24119555]
    MCF7 IC50
    0.45 μM
    Compound: 6; SAHA
    Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MCF7 IC50
    0.58 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    MCF7 GI50
    0.61 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 25800646]
    MCF7 EC50
    0.65 μM
    Compound: 3; SAHA
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    		[PMID: 31627059]
    MCF7 IC50
    0.65 μM
    Compound: 2
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 28953386]
    MCF7 IC50
    0.65 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 27541357]
    MCF7 GI50
    0.689 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells after 48 hrs by Sulforhodamine B assay
    Cytotoxicity against human MCF7 cells after 48 hrs by Sulforhodamine B assay
    		[PMID: 23639537]
    MCF7 IC50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 32151834]
    MCF7 IC50
    0.81 μM
    Compound: 4
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    MCF7 IC50
    0.9 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    MCF7 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    MCF7 IC50
    0.95 μM
    Compound: 6; SAHA
    Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MCF7 IC50
    1.04 μM
    Compound: SAHA
    Antiproliferative against human MCF-7 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative against human MCF-7 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 33045329]
    MCF7 IC50
    1.1 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		[PMID: 24766560]
    MCF7 IC50
    1.11 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    MCF7 IC50
    1.15 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 21924799]
    MCF7 GI50
    1.25 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured after 6 days by WST8 assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured after 6 days by WST8 assay
    		[PMID: 34610548]
    MCF7 IC50
    1.26 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells incubated for 96 hrs by resazurin assay
    Antiproliferative activity against human MCF7 cells incubated for 96 hrs by resazurin assay
    		[PMID: 32435375]
    MCF7 GI50
    1.34 μM
    Compound: 1, SAHA
    Growth inhibition of human MCF7 cells after 96 hrs by MTT assay
    Growth inhibition of human MCF7 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    MCF7 IC50
    1.6 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 24296013]
    MCF7 IC50
    1.6 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    		[PMID: 29360358]
    MCF7 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    MCF7 GI50
    17.9 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 28629630]
    MCF7 GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
    Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 22435669]
    MCF7 IC50
    2 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    		[PMID: 32738414]
    MCF7 IC50
    2.18 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 29396364]
    MCF7 GI50
    2.19 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    MCF7 GI50
    2.2 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    MCF7 IC50
    2.29 μM
    Compound: Vorinostat
    Cytotoxicity against human MCF7 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
    		[PMID: 23829483]
    MCF7 IC50
    2.36 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
    		[PMID: 35043615]
    MCF7 IC50
    2.5 μM
    Compound: SAHA; vorinostat
    Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
    Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
    		[PMID: 26725029]
    MCF7 IC50
    2.5 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    MCF7 IC50
    2.5 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33965842]
    MCF7 IC50
    2.5 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    		[PMID: 25993269]
    MCF7 IC50
    2.6 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
    		[PMID: 34624191]
    MCF7 GI50
    2.6 μM
    Compound: SAHA
    Antiproliferative activity against human MCF-7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human MCF-7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    		[PMID: 34500130]
    MCF7 IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay
    		[PMID: 29317150]
    MCF7 IC50
    2.7 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability in presence of erlotinib by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability in presence of erlotinib by MTT assay
    		[PMID: 32320239]
    MCF7 IC50
    2.8 μM
    Compound: Vorinostat
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 32791404]
    MCF7 IC50
    2.8 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after hrs by ATP content assay
    Antiproliferative activity against human MCF7 cells after hrs by ATP content assay
    		[PMID: 20143778]
    MCF7 IC50
    2.81 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 21714538]
    MCF7 IC50
    2.9 μM
    Compound: Vorinostat
    Antiproliferative activity against human MCF7 cells by CCK8 assay
    Antiproliferative activity against human MCF7 cells by CCK8 assay
    		[PMID: 30660827]
    MCF7 IC50
    28.66 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		10.1039/C5MD00247H
    MCF7 GI50
    29.1 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay
    		[PMID: 27614919]
    MCF7 IC50
    3.26 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    MCF7 IC50
    3.27 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    MCF7 IC50
    3.27 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells by MTT assay
    Antiproliferative activity against human MCF7 cells by MTT assay
    		[PMID: 31546197]
    MCF7 IC50
    3.47 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    MCF7 IC50
    3.49 μM
    Compound: SAHA
    Antiproliferative activity in human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    Antiproliferative activity in human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    		[PMID: 32061484]
    MCF7 IC50
    3.78 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    MCF7 IC50
    3.78 μM
    Compound: SA, SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    MCF7 CC50
    3000 nM
    Compound: 1
    Antiproliferative activity against human MCF7 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    MCF7 IC50
    354 nM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    MCF7 IC50
    38.2 μM
    Compound: SAHA
    Cytotoxic activity against human MCF7 cells after 24 hrs by MTT assay
    Cytotoxic activity against human MCF7 cells after 24 hrs by MTT assay
    		[PMID: 29496367]
    MCF7 IC50
    4.1 μM
    Compound: 5; SAHA
    Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    MCF7 IC50
    4.2 μM
    Compound: Vorinostat
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 26741358]
    MCF7 IC50
    4.2 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 32320239]
    MCF7 IC50
    4.339 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    		[PMID: 34454126]
    MCF7 IC50
    4.4 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against human MCF7 cells expressing ERalpha and ERbeta assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells expressing ERalpha and ERbeta assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23786452]
    MCF7 IC50
    4.48 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 29288941]
    MCF7 IC50
    4.5 μM
    Compound: Vorinostat
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 26475519]
    MCF7 IC50
    4.69 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    		[PMID: 28987602]
    MCF7 IC50
    4.78 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 37116762]
    MCF7 IC50
    4.83 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
    		[PMID: 30045621]
    MCF7 IC50
    5.15 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    		[PMID: 35272009]
    MCF7 IC50
    5.15 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells measured after 72 hrs
    Antiproliferative activity against human MCF7 cells measured after 72 hrs
    		[PMID: 35697181]
    MCF7 IC50
    5.43 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    MCF7 IC50
    54.55 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		10.1039/C5MD00247H
    MCF7 IC50
    6 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MCF7 cells up to 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells up to 72 hrs by MTT assay
    		[PMID: 27541357]
    MCF7 IC50
    6.17 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    		[PMID: 32180916]
    MCF7 IC50
    6.42 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
    		[PMID: 24185378]
    MCF7 IC50
    6.5 μM
    Compound: Vorinostat
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    		[PMID: 35608269]
    MCF7 IC50
    60.2 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
    Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 24095016]
    MCF7 IC50
    637.2 nM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    MCF7 IC50
    7.11 μM
    Compound: 1; SAHA
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    MCF7 IC50
    8.5 μM
    Compound: 3, SAHA
    Cytotoxicity against human MCF7 cells after 96 hrs by MTA reduction assay
    Cytotoxicity against human MCF7 cells after 96 hrs by MTA reduction assay
    		[PMID: 23293738]
    MCF7 GI50
    8.6 μM
    Compound: 1, SAHA
    Growth inhibition of human MCF7 cells after 72 hrs by XTT assay
    Growth inhibition of human MCF7 cells after 72 hrs by XTT assay
    		[PMID: 24900500]
    MCF7 IC50
    9.59 μM
    Compound: SAHA
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		10.1039/C5MD00247H
    MCF7 IC50
    9.798 μM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    MCF7 IC50
    939.97 nM
    Compound: SAHA
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    		[PMID: 30819618]
    MDA-MB-231 IC50
    > 100 μM
    Compound: 1; SAHA
    Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28885834]
    MDA-MB-231 IC50
    > 411 nM
    Compound: Vorinostat
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    MDA-MB-231 IC50
    0.16 μM
    Compound: SAHA, Vorinostat
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 24095016]
    MDA-MB-231 IC50
    0.201 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by resazurin dye based fluorescence assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by resazurin dye based fluorescence assay
    		[PMID: 29456804]
    MDA-MB-231 IC50
    0.43 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 5 days by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 5 days by MTT assay
    		[PMID: 28601509]
    MDA-MB-231 IC50
    0.61 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    		[PMID: 34237620]
    MDA-MB-231 IC50
    0.61 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin resistant human MDA-MB-231 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin resistant human MDA-MB-231 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    MDA-MB-231 IC50
    0.61 μM
    Compound: SAHA, vorinostat
    Inhibition of HDAC in cisplatin sensitive human MDA-MB-231 cells after 18 hrs by fluorescence assay
    Inhibition of HDAC in cisplatin sensitive human MDA-MB-231 cells after 18 hrs by fluorescence assay
    		[PMID: 23252603]
    MDA-MB-231 IC50
    0.61 μM
    Compound: 6; SAHA
    Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MDA-MB-231 GI50
    0.66 μM
    Compound: 1, SAHA
    Growth inhibition of human MDA-MB-231 cells by SRB assay
    Growth inhibition of human MDA-MB-231 cells by SRB assay
    		[PMID: 17477518]
    MDA-MB-231 GI50
    0.66 μM
    Compound: 2, SAHA
    Antiproliferative activity against human MDA-MB-231 cells by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells by SRB assay
    		[PMID: 16723227]
    MDA-MB-231 GI50
    0.89 μM
    Compound: SAHA
    Growth inhibition of human MDA-MB-231 cells after 21 hrs by MTT assay
    Growth inhibition of human MDA-MB-231 cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    MDA-MB-231 IC50
    0.96 μM
    Compound: 6; SAHA
    Antiproliferative activity against human MDA-MB-231 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
    Antiproliferative activity against human MDA-MB-231 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
    		[PMID: 26613635]
    MDA-MB-231 GI50
    0.97 μM
    Compound: 1, SAHA
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
    		[PMID: 22439863]
    MDA-MB-231 IC50
    0.97 μM
    Compound: 6; SAHA
    Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
    		[PMID: 30078609]
    MDA-MB-231 GI50
    1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
    Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 22435669]
    MDA-MB-231 IC50
    1.09 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    		[PMID: 33586434]
    MDA-MB-231 IC50
    1.11 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    MDA-MB-231 IC50
    1.18 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 21733698]
    MDA-MB-231 IC50
    1.19 μM
    Compound: 2
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 28953386]
    MDA-MB-231 IC50
    1.19 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 27541357]
    MDA-MB-231 EC50
    1.2 μM
    Compound: 3; SAHA
    Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
    		[PMID: 31627059]
    MDA-MB-231 IC50
    1.29 μM
    Compound: SAHA
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 24702857]
    MDA-MB-231 IC50
    1.31 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    MDA-MB-231 IC50
    1.35 μM
    Compound: Vorinostat
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    MDA-MB-231 IC50
    1.49 μM
    Compound: 4
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    MDA-MB-231 IC50
    1.54 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    MDA-MB-231 IC50
    1.66 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin sensitive human MDA-MB-231 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin sensitive human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    MDA-MB-231 IC50
    1.72 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    MDA-MB-231 IC50
    1.72 μM
    Compound: SA, SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    MDA-MB-231 IC50
    1.73 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 26907204]
    MDA-MB-231 IC50
    1.77 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 34043359]
    MDA-MB-231 IC50
    1.8 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay
    		10.1039/C4MD00211C
    MDA-MB-231 GI50
    1.81 μM
    Compound: 1, SAHA
    Growth inhibition of human MDA-MB-231 cells after 96 hrs by MTT assay
    Growth inhibition of human MDA-MB-231 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    MDA-MB-231 IC50
    1.91 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 21924799]
    MDA-MB-231 IC50
    1.98 μM
    Compound: SAHA
    Anti-proliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    MDA-MB-231 IC50
    13.48 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    MDA-MB-231 IC50
    1710 nM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    MDA-MB-231 GI50
    2 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    MDA-MB-231 GI50
    2 μM
    Compound: 2, SAHA
    Growth inhibition of human MDA-MB-231 cells by SRB assay
    Growth inhibition of human MDA-MB-231 cells by SRB assay
    		[PMID: 17904843]
    MDA-MB-231 GI50
    2 μM
    Compound: SAHA
    Growth inhibition of human MDA-MB-231 cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human MDA-MB-231 cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    MDA-MB-231 GI50
    2 μM
    Compound: SAHA
    Growth inhibition of human MDA-MB-231 cells after 5 days by sulforhodamine B assay
    Growth inhibition of human MDA-MB-231 cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    MDA-MB-231 IC50
    2.02 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26149591]
    MDA-MB-231 IC50
    2.03 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    MDA-MB-231 IC50
    2.11 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after hrs by ATP content assay
    Antiproliferative activity against human MDA-MB-231 cells after hrs by ATP content assay
    		[PMID: 20143778]
    MDA-MB-231 IC50
    2.23 μM
    Compound: SAHA
    Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    MDA-MB-231 IC50
    2.29 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 25311567]
    MDA-MB-231 GI50
    2.32 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    MDA-MB-231 IC50
    2.36 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by MTT assay
    		[PMID: 34847495]
    MDA-MB-231 GI50
    2.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTS assay
    Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    MDA-MB-231 GI50
    2.5 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    MDA-MB-231 IC50
    2.59 μM
    Compound: Vorinostat
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    MDA-MB-231 GI50
    2.67 μM
    Compound: 1; SAHA
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 28395150]
    MDA-MB-231 IC50
    2.69 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against cisplatin resistant human MDA-MB-231 cells after 72 hrs by MTT assay
    Cytotoxicity against cisplatin resistant human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 23252603]
    MDA-MB-231 GI50
    2.73 μM
    Compound: Vorinostat
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    		[PMID: 36262394]
    MDA-MB-231 IC50
    2.8 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter blue-reagent based assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter blue-reagent based assay
    		[PMID: 30645113]
    MDA-MB-231 IC50
    3 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 7 days
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 7 days
    		[PMID: 35643262]
    MDA-MB-231 IC50
    3.02 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    MDA-MB-231 IC50
    3.07 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36153841]
    MDA-MB-231 IC50
    3.3 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    MDA-MB-231 IC50
    3.31 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    MDA-MB-231 IC50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity in human MDA-MB-231 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    Antiproliferative activity in human MDA-MB-231 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    		[PMID: 32061484]
    MDA-MB-231 IC50
    3.4 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against ERalpha and ERbeta-deficient human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against ERalpha and ERbeta-deficient human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23786452]
    MDA-MB-231 IC50
    3.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
    		[PMID: 35255412]
    MDA-MB-231 IC50
    3.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
    		[PMID: 33261898]
    MDA-MB-231 IC50
    3.96 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    		[PMID: 25874326]
    MDA-MB-231 IC50
    4.5 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
    		[PMID: 27541357]
    MDA-MB-231 IC50
    4.53 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 28757101]
    MDA-MB-231 IC50
    4.585 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    MDA-MB-231 IC50
    4.61 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 26216016]
    MDA-MB-231 IC50
    4.61 μM
    Compound: 1, SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 24525003]
    MDA-MB-231 IC50
    4.66 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by SRB assay
    		[PMID: 32180916]
    MDA-MB-231 IC50
    4.93 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 29954683]
    MDA-MB-231 IC50
    5.52 μM
    Compound: Vorinostat
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 35477142]
    MDA-MB-231 IC50
    5.6 μM
    Compound: 1, SAHA
    Inhibition of human MDA-MB-231 cell proliferation after 48 hrs by MTT assay
    Inhibition of human MDA-MB-231 cell proliferation after 48 hrs by MTT assay
    		[PMID: 23493449]
    MDA-MB-231 IC50
    5.8 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    MDA-MB-231 IC50
    6.04 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth measured after 2 days by CCK8 assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth measured after 2 days by CCK8 assay
    		[PMID: 34610548]
    MDA-MB-231 IC50
    6000 nM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    		[PMID: 27665180]
    MDA-MB-231 IC50
    7.4 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 25815139]
    MDA-MB-231 IC50
    8.14 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
    		[PMID: 32791401]
    MDA-MB-231 IC50
    8.25 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 34656899]
    MDA-MB-435 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTS assay
    Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    MDA-MB-435 GI50
    0.88 μM
    Compound: 1, SAHA
    Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 24119555]
    MDA-MB-435 GI50
    1.18 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 25800646]
    MDA-MB-436 IC50
    3.9 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-436 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human MDA-MB-436 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    MDA-MB-453 IC50
    0.37 μM
    Compound: 5; SAHA
    Antiproliferative activity against human MDA-MB-453 cells after 96 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-453 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    MDA-MB-468 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTS assay
    Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    MDA-MB-468 IC50
    0.95 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-468 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-468 cells incubated for 72 hrs by MTT assay
    		[PMID: 32961382]
    MDA-MB-468 IC50
    10.03 μM
    Compound: SAHA
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    MDA-MB-468 IC50
    2.69 μM
    Compound: Vorinostat
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    MDA-MB-468 IC50
    2.75 μM
    Compound: SAHA
    Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
    		[PMID: 33586434]
    MDA-MB-468 IC50
    2.85 μM
    Compound: SAHA
    Anticancer activity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    MEF IC50
    4.4 μM
    Compound: SAHA
    Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay
    Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay
    		[PMID: 23570542]
    MG-63 GI50
    > 10 μM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human MG63 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human MG63 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    MGC-803 IC50
    1.54 μM
    Compound: SAHA
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
    		[PMID: 33957387]
    MGC-803 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    MGC-803 IC50
    2.678 μM
    Compound: SAHA
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
    		[PMID: 34454126]
    MGC-803 IC50
    3.51 μM
    Compound: SAHA
    Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    MGC-803 IC50
    8.67 μM
    Compound: Vorinostat
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    		[PMID: 33831778]
    MGC-803 IC50
    8.75 μM
    Compound: SAHA
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    		[PMID: 28987602]
    MGC-803 IC50
    9.74 μM
    Compound: SAHA
    Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    MIA PaCa-2 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human MiaPaca2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MiaPaca2 cells after 72 hrs by MTT assay
    		[PMID: 18642892]
    MIA PaCa-2 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human MIAPaCa2 cells by MTT assay
    Antiproliferative activity against human MIAPaCa2 cells by MTT assay
    		[PMID: 19419863]
    MIA PaCa-2 IC50
    1.1 μM
    Compound: 1a, SAHA
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay
    		[PMID: 20055418]
    MIA PaCa-2 IC50
    1.1 μM
    Compound: SAHA
    Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay
    Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay
    		[PMID: 18494463]
    MIA PaCa-2 IC50
    2.2 μM
    Compound: SAHA
    Cytotoxicity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    MIA PaCa-2 GI50
    3500 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    MIA PaCa-2 GI50
    790 nM
    Compound: SAHA
    Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
    		[PMID: 24999749]
    MKN-45 IC50
    1.25 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human MKN45 cells by MTT assay
    Cytotoxicity against human MKN45 cells by MTT assay
    		[PMID: 24766560]
    MKN-45 GI50
    7.3 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human MKN45 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MKN45 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    MM1.S IC50
    0.82 μM
    Compound: SAHA
    Antiproliferative activity against human MM1S cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Antiproliferative activity against human MM1S cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 26890114]
    MM1.S IC50
    1.54 μM
    Compound: SAHA
    Cytotoxicity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
    Cytotoxicity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
    		[PMID: 35119267]
    MM1.S IC50
    2844 nM
    Compound: SAHA
    Antiproliferative activity against human MM1S cells after 72 hrs by MTS assay
    Antiproliferative activity against human MM1S cells after 72 hrs by MTS assay
    		[PMID: 29795767]
    MM1.S IC50
    573 nM
    Compound: SAHA
    Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
    Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    MM1.S IC50
    590.3 nM
    Compound: SAHA
    Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
    Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    MM473 IC50
    > 10 μM
    Compound: SAHA
    Antiproliferative activity against human MM473 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human MM473 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    MM473 IC50
    8.2 μM
    Compound: SAHA
    Antiproliferative activity against human MM473 cells at 10 uM after 72 hrs by MTT assay relative to control
    Antiproliferative activity against human MM473 cells at 10 uM after 72 hrs by MTT assay relative to control
    		[PMID: 29150335]
    MM96L EC50
    0.01 μM
    Compound: 25a
    Antiproliferative activity against human MM96L cells assessed as cell growth inhibition by SRB assay
    Antiproliferative activity against human MM96L cells assessed as cell growth inhibition by SRB assay
    		[PMID: 34591488]
    MOLM-13 IC50
    0.345 μM
    Compound: 1; SAHA
    Cytotoxicity against human MOLM13 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
    Cytotoxicity against human MOLM13 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
    		[PMID: 31938464]
    MOLM-13 EC50
    1.2 μM
    Compound: SAHA
    Growth inhibition of human MOLM13 cells after 44 hrs by MTT assay
    Growth inhibition of human MOLM13 cells after 44 hrs by MTT assay
    		[PMID: 28337317]
    MOLM-13 IC50
    984.9 nM
    Compound: SAHA
    Antiproliferative activity against human MOLM13 cells harboring wild type p53/FLT3-ITD mutant after 72 hrs by MTT assay
    Antiproliferative activity against human MOLM13 cells harboring wild type p53/FLT3-ITD mutant after 72 hrs by MTT assay
    		[PMID: 27505848]
    MOLM-14 EC50
    0.54 μM
    Compound: 3; SAHA
    Antiproliferative activity against human MOLM14 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    Antiproliferative activity against human MOLM14 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 31627059]
    MOLT-4 IC50
    0.33 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    		[PMID: 28336407]
    MOLT-4 IC50
    0.36 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    MOLT-4 IC50
    0.38 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells incubated for 24 hrs by CCK8 assay
    Antiproliferative activity against human MOLT4 cells incubated for 24 hrs by CCK8 assay
    		[PMID: 32247729]
    MOLT-4 GI50
    0.4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human MOLT4 cells after 72 hrs by MTS assay
    Growth inhibition of human MOLT4 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    MOLT-4 IC50
    0.4 μM
    Compound: 3; SAHA
    Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 30901208]
    MOLT-4 IC50
    0.41 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT-4 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human MOLT-4 cells after 48 hrs by CCK-8 assay
    		[PMID: 35939996]
    MOLT-4 IC50
    0.41 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    MOLT-4 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human MOLT-4 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human MOLT-4 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    MOLT-4 IC50
    0.52 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    MOLT-4 IC50
    0.56 μM
    Compound: Vorinostat
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    		[PMID: 28371677]
    MOLT-4 GI50
    0.68 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human MOLT4 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human MOLT4 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    MOLT-4 IC50
    0.7 μM
    Compound: SAHA
    Cytotoxicity against human MOLT4 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MOLT4 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    MOLT-4 IC50
    1.08 μM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
    		[PMID: 29500131]
    MOLT-4 GI50
    542 nM
    Compound: SAHA
    Antiproliferative activity against human MOLT4 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human MOLT4 cells after 72 hrs by CCK8 assay
    		[PMID: 26331334]
    MOLT-4 GI50
    670 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human MOLT4 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human MOLT4 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    MRC5 IC50
    68.7 μM
    Compound: SAHA
    Anti-proliferative activity against human MRC5 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human MRC5 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    MV4-11 EC50
    < 30 nM
    Compound: Vorinostat
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-blue cell viability assay
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-blue cell viability assay
    		[PMID: 27754681]
    MV4-11 IC50
    0.24 μM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs in presence of SHP099 by CCK-8 assay
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs in presence of SHP099 by CCK-8 assay
    		[PMID: 36097406]
    MV4-11 IC50
    0.26 μM
    Compound: 10; SAHA
    Antiproliferative activity against human MV4-11 cells assessed as cell viability after 72 hrs by CCK8 assay
    Antiproliferative activity against human MV4-11 cells assessed as cell viability after 72 hrs by CCK8 assay
    		[PMID: 33077265]
    MV4-11 IC50
    0.29 μM
    Compound: SAHA
    Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
    Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
    		[PMID: 35119267]
    MV4-11 IC50
    0.31 μM
    Compound: 1; SAHA
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
    		[PMID: 31938464]
    MV4-11 IC50
    0.38 μM
    Compound: SAHA
    Cytotoxicity against human MV4-11 cells assessed as cell viability incubated for 72 hrs by Cell titer-blue assay
    Cytotoxicity against human MV4-11 cells assessed as cell viability incubated for 72 hrs by Cell titer-blue assay
    		[PMID: 34101461]
    MV4-11 IC50
    0.43 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    		[PMID: 29360358]
    MV4-11 IC50
    0.5 μM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    MV4-11 IC50
    0.5 μM
    Compound: SAHA
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30034592]
    MV4-11 EC50
    0.53 μM
    Compound: Vor; SAHA
    Induction of cell death in human MV4-11 cells measured at 48 hrs by fluorescence based microplate reader analysis
    Induction of cell death in human MV4-11 cells measured at 48 hrs by fluorescence based microplate reader analysis
    		[PMID: 29360358]
    MV4-11 GI50
    0.59 μM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human MV4-11 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
    		[PMID: 25800646]
    MV4-11 IC50
    0.68 μM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
    		[PMID: 36272186]
    MV4-11 IC50
    0.72 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
    		[PMID: 27142751]
    MV4-11 IC50
    0.85 μM
    Compound: 1; SAHA
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36153841]
    MV4-11 EC50
    0.9 μM
    Compound: Vor; SAHA
    Induction of apoptosis in human MV4-11 cells assessed as increase in caspase 3/7 activity measured at 24 hrs in presence of Z-DEVD-R110 or (Z-Asp-Glu-Val-Asp)2-rhodamine110 by fluorescence based microplate reader analysis
    Induction of apoptosis in human MV4-11 cells assessed as increase in caspase 3/7 activity measured at 24 hrs in presence of Z-DEVD-R110 or (Z-Asp-Glu-Val-Asp)2-rhodamine110 by fluorescence based microplate reader analysis
    		[PMID: 29360358]
    MV4-11 IC50
    0.98 μM
    Compound: 5; SAHA
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    		[PMID: 28765013]
    MV4-11 IC50
    220 nM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    MV4-11 IC50
    230 nM
    Compound: SAHA
    Cytotoxicity against human MV4-11 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human MV4-11 cells assessed as growth inhibition after 24 hrs by MTT assay
    		[PMID: 27186676]
    MV4-11 EC50
    418.1 nM
    Compound: SAHA; Vor
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Blue dye based spectrophotometric analysis
    Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Blue dye based spectrophotometric analysis
    		[PMID: 32321249]
    MV4-11 IC50
    439 nM
    Compound: SAHA
    Growth inhibition of human MV4-11 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
    Growth inhibition of human MV4-11 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
    		10.1039/C3MD00285C
    MV4-11 IC50
    496.1 nM
    Compound: SAHA
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    MV4-11 IC50
    85 nM
    Compound: SAHA
    Cytotoxicity against human MV4-11 cells after 72 hrs by MTT assay
    Cytotoxicity against human MV4-11 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    N2a IC50
    1.45 μM
    Compound: SAHA
    Cytotoxicity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 24 hrs by Cell Titer-Glo 2.0 Luminescent cell assay
    Cytotoxicity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 24 hrs by Cell Titer-Glo 2.0 Luminescent cell assay
    		[PMID: 33845233]
    NALM-6 IC50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    		[PMID: 36395680]
    NAMALVA IC50
    0.11 μM
    Compound: 1; SAHA
    Cytotoxicity against human NAMALVA cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human NAMALVA cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33668008]
    NB1 IC50
    2.71 μM
    Compound: Vorinostat
    Antiproliferative activity against human NB-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    Antiproliferative activity against human NB-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    		[PMID: 31391882]
    NB-4 IC50
    0.6 μM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human NB4 cells after 48 hrs
    Antiproliferative activity against human NB4 cells after 48 hrs
    		[PMID: 18723349]
    NB-4 IC50
    0.7 μM
    Compound: SAHA, vorinostat
    Growth inhibition of human NB4 cells by SRB assay
    Growth inhibition of human NB4 cells by SRB assay
    		[PMID: 17892933]
    NB-4 IC50
    0.7 μM
    Compound: SAHA
    Growth inhibition of human NB4 cells after 72 hrs
    Growth inhibition of human NB4 cells after 72 hrs
    		[PMID: 26376355]
    NB-4 IC50
    0.7 μM
    Compound: SAHA
    Antiproliferative activity against human NB4 cells after 72 hrs
    Antiproliferative activity against human NB4 cells after 72 hrs
    		[PMID: 19084294]
    NB-4 IC50
    0.98 μM
    Compound: SAHA, Vorinostat
    Induction of apoptosis in human NB4 cells after 48 hrs by Annexin V test
    Induction of apoptosis in human NB4 cells after 48 hrs by Annexin V test
    		[PMID: 23792316]
    NB-4 IC50
    1.2 μM
    Compound: SAHA
    Antiproliferative activity against human NB-4 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human NB-4 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    NB-4 IC50
    1.52 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human NB4 cells after 48 hrs by MTT assay
    Cytotoxicity against human NB4 cells after 48 hrs by MTT assay
    		[PMID: 21476600]
    NB-4 IC50
    3.3 μM
    Compound: SAHA
    Antiproliferative activity against human NB4 cells after 72 hrs by MTT assay
    Antiproliferative activity against human NB4 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    NB-4 IC50
    880 nM
    Compound: Vorinostat
    Cytotoxicity against human NB-4 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human NB-4 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    NCI/ADR-RES GI50
    0.16 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-ADR-RES cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-ADR-RES cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI/ADR-RES IC50
    1413.4 nM
    Compound: SAHA
    Cytotoxicity against human MCF7/ADR cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7/ADR cells after 72 hrs by SRB assay
    		[PMID: 30819618]
    NCI-H1299 IC50
    0.55 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H1299 by SRB assay
    Cytotoxicity against human NCI-H1299 by SRB assay
    		[PMID: 20855208]
    NCI-H1299 IC50
    3.46 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    NCI-H1299 IC50
    4.92 μM
    Compound: 1; SAHA
    Antiproliferative activity against human NCI-H1299 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human NCI-H1299 cells after 72 hrs by CCK8 assay
    		[PMID: 30045621]
    NCI-H1299 IC50
    5.1 μM
    Compound: 5; SAHA
    Antiproliferative activity against human NCI-H1299 cells after 96 hrs by MTT assay
    Antiproliferative activity against human NCI-H1299 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    NCI-H1299 IC50
    5.53 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H1299 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human NCI-H1299 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    NCI-H1299 IC50
    7.02 μM
    Compound: SAHA
    Antiproliferative activity against human H1299 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human H1299 cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    NCI-H1581 IC50
    2.501 μM
    Compound: SAHA
    Cytotoxicity against human NCI-1581 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human NCI-1581 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    NCI-H1975 GI50
    0.98 μM
    Compound: 1; SAHA
    Growth inhibition of human NCI-H1975 cells incubated for 48 hrs by SRB assay
    Growth inhibition of human NCI-H1975 cells incubated for 48 hrs by SRB assay
    		[PMID: 32058238]
    NCI-H1975 GI50
    1.41 μM
    Compound: SAHA; 1
    Antiproliferative activity against human NCI-H1975 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human NCI-H1975 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 29567459]
    NCI-H1975 IC50
    1.9 μM
    Compound: 8
    Antiproliferative activity against human NCI-H1975 expressing EGFR T790M/L858R mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H1975 expressing EGFR T790M/L858R mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
    		[PMID: 27769671]
    NCI-H1975 IC50
    2.04 μM
    Compound: Vorinostat
    Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    NCI-H1975 GI50
    2.61 μM
    Compound: 1; SAHA
    Antiproliferative activity against human NCI-H1975 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human NCI-H1975 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
    		[PMID: 31655430]
    NCI-H2126 IC50
    1.319 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H2126 by SRB assay
    Cytotoxicity against human NCI-H2126 by SRB assay
    		[PMID: 20855208]
    NCI-H226 IC50
    3.48 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H226 by SRB assay
    Cytotoxicity against human NCI-H226 by SRB assay
    		[PMID: 20855208]
    NCI-H226 GI50
    4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-H226 cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-H226 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI-H226 IC50
    8.33 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    NCI-H23 IC50
    0.383 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H23 by SRB assay
    Cytotoxicity against human NCI-H23 by SRB assay
    		[PMID: 20855208]
    NCI-H23 GI50
    0.92 μM
    Compound: 1, SAHA
    Growth inhibition of NCI-H23 cells by SRB assay
    Growth inhibition of NCI-H23 cells by SRB assay
    		[PMID: 17477518]
    NCI-H23 GI50
    0.92 μM
    Compound: 2, SAHA
    Antiproliferative activity against human NCI-H23 cells by SRB assay
    Antiproliferative activity against human NCI-H23 cells by SRB assay
    		[PMID: 16723227]
    NCI-H23 GI50
    1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-H23 cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-H23 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI-H23 GI50
    1.34 μM
    Compound: SAHA
    Growth inhibition of human NCI-H23 cells after 21 hrs by MTT assay
    Growth inhibition of human NCI-H23 cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    NCI-H23 IC50
    1.44 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H23 cells by colorimetric method
    Cytotoxicity against human NCI-H23 cells by colorimetric method
    		[PMID: 32916298]
    NCI-H23 GI50
    2 μM
    Compound: SAHA; NSC759852
    Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition at 10 uM incubated for 24 hrs by MTT assay
    Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition at 10 uM incubated for 24 hrs by MTT assay
    		[PMID: 36306372]
    NCI-H23 GI50
    2.34 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human NCI-H23 cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human NCI-H23 cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    NCI-H23 GI50
    2.34 μM
    Compound: SAHA
    Growth inhibition of human NCI-H23 cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human NCI-H23 cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    NCI-H23 GI50
    2.34 μM
    Compound: SAHA
    Growth inhibition of human NCI-H23 cells after 5 days by sulforhodamine B assay
    Growth inhibition of human NCI-H23 cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    NCI-H23 IC50
    2.8 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H23 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human NCI-H23 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    NCI-H23 IC50
    3.2 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H23 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H23 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 31546197]
    NCI-H292 IC50
    1.11 μM
    Compound: SAHA
    Growth inhibition of human NCI-H292 cells after 72 hrs by MTT assay
    Growth inhibition of human NCI-H292 cells after 72 hrs by MTT assay
    		[PMID: 28108250]
    NCI-H292 IC50
    2.01 μM
    Compound: SAHA
    Growth inhibition of human NCI-H292 cells in LDL depleted FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
    Growth inhibition of human NCI-H292 cells in LDL depleted FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
    		[PMID: 28108250]
    NCI-H292 IC50
    4.61 μM
    Compound: SAHA
    Growth inhibition of human NCI-H292 cells in FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
    Growth inhibition of human NCI-H292 cells in FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
    		[PMID: 28108250]
    NCI-H292 IC50
    5.15 μM
    Compound: SAHA
    Growth inhibition of human NCI-H292 cells after 72 hrs in presence of LDL by MTT assay
    Growth inhibition of human NCI-H292 cells after 72 hrs in presence of LDL by MTT assay
    		[PMID: 28108250]
    NCI-H322M GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-H322M cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-H322M cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI-H358 IC50
    2.5 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H358 cells after hrs by ATP content assay
    Antiproliferative activity against human NCI-H358 cells after hrs by ATP content assay
    		[PMID: 20143778]
    NCI-H441 IC50
    0.686 μM
    Compound: SAHA
    Cytotoxicity against human H441 by SRB assay
    Cytotoxicity against human H441 by SRB assay
    		[PMID: 20855208]
    NCI-H460 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human H460 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    NCI-H460 IC50
    0.425 μM
    Compound: 1; SAHA
    Antiproliferative activity against human NCI-H460 cells after 72 hrs by resazurin dye based fluorescence assay
    Antiproliferative activity against human NCI-H460 cells after 72 hrs by resazurin dye based fluorescence assay
    		[PMID: 29456804]
    NCI-H460 GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-H460 cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-H460 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI-H460 IC50
    0.82 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human H460 cells by MTT assay
    Cytotoxicity against human H460 cells by MTT assay
    		[PMID: 24766560]
    NCI-H460 GI50
    0.85 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 25800646]
    NCI-H460 GI50
    0.85 μM
    Compound: 1, SAHA
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 24119555]
    NCI-H460 GI50
    1 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H460 cells by MTT assay
    Cytotoxicity against human NCI-H460 cells by MTT assay
    		[PMID: 23538115]
    NCI-H460 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H460 cells after 72 hrs by SRB assay
    Antiproliferative activity against human NCI-H460 cells after 72 hrs by SRB assay
    		[PMID: 29150335]
    NCI-H460 IC50
    1 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
    		[PMID: 30660827]
    NCI-H460 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    NCI-H460 IC50
    1.7 μM
    Compound: SAHA
    Antiproliferative activity against human H460 cells after hrs by ATP content assay
    Antiproliferative activity against human H460 cells after hrs by ATP content assay
    		[PMID: 20143778]
    NCI-H460 IC50
    100 μM
    Compound: 5; SAHA
    Antiproliferative activity against human NCI-H460 cells after 96 hrs by MTT assay
    Antiproliferative activity against human NCI-H460 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    NCI-H460 IC50
    11.92 μM
    Compound: SAHA
    Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    		[PMID: 31991336]
    NCI-H460 IC50
    2.77 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by SRB assay
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by SRB assay
    		[PMID: 24185378]
    NCI-H460 IC50
    3.04 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    NCI-H460 IC50
    3.4 μM
    Compound: 2, SAHA
    Growth inhibition of human H460 cells after 48 hrs by SRB assay
    Growth inhibition of human H460 cells after 48 hrs by SRB assay
    		[PMID: 21073160]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA, vorinostat
    Growth inhibition of human H460 cells by SRB assay
    Growth inhibition of human H460 cells by SRB assay
    		[PMID: 17892933]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA
    Cytotoxicity against human H460 cells after 24 hrs by sulforhodamine B assay
    Cytotoxicity against human H460 cells after 24 hrs by sulforhodamine B assay
    		[PMID: 19359173]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity against human H460 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    Antiproliferative activity against human H460 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
    		[PMID: 26890116]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA
    Growth inhibition of human H460 cells after 72 hrs
    Growth inhibition of human H460 cells after 72 hrs
    		[PMID: 26376355]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity against human H460 cells assessed as growth inhibition after 72 hrs
    Antiproliferative activity against human H460 cells assessed as growth inhibition after 72 hrs
    		[PMID: 24742384]
    NCI-H460 IC50
    3.4 μM
    Compound: SAHA
    Antiproliferative activity against human H460 cells after 72 hrs
    Antiproliferative activity against human H460 cells after 72 hrs
    		[PMID: 19084294]
    NCI-H460 IC50
    3.448 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H460 by SRB assay
    Cytotoxicity against human NCI-H460 by SRB assay
    		[PMID: 20855208]
    NCI-H460 IC50
    4.136 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    NCI-H460 IC50
    4.2 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H460 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human NCI-H460 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    NCI-H460 IC50
    5.46 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    NCI-H460 IC50
    6.29 μM
    Compound: Vorinostat
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    NCI-H460 GI50
    8 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    		[PMID: 20605448]
    NCI-H522 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human NCI-H522 cells after 72 hrs by MTS assay
    Growth inhibition of human NCI-H522 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    NCI-H522 IC50
    0.832 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H522 by SRB assay
    Cytotoxicity against human NCI-H522 by SRB assay
    		[PMID: 20855208]
    NCI-H522 IC50
    1.72 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
    Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
    		[PMID: 35984756]
    NCI-H522 IC50
    2.38 μM
    Compound: SAHA
    Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    NCI-H526 GI50
    0.481 μM
    Compound: Vorinostat
    Antiproliferative activity against human NCI-H526 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    Antiproliferative activity against human NCI-H526 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
    		[PMID: 36262394]
    NCI-H661 IC50
    0.13 μM
    Compound: Vorinostat
    Antiproliferative activity against human NCI-H661 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H661 cells incubated for 72 hrs by MTT assay
    		[PMID: 25953722]
    NCI-H661 IC50
    0.13 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    		[PMID: 25874326]
    NCI-H661 IC50
    1 μM
    Compound: 1
    Antiproliferative activity against human H661 cells after 48 hrs
    Antiproliferative activity against human H661 cells after 48 hrs
    		[PMID: 17157009]
    NCI-H661 IC50
    5 μM
    Compound: SAHA
    Antiproliferative activity against H661 cells after 48 hrs
    Antiproliferative activity against H661 cells after 48 hrs
    		[PMID: 17897824]
    NCI-H69 EC50
    2.06 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H69 cells after 72 hrs by trypan blue exclusion assay
    Cytotoxicity against human NCI-H69 cells after 72 hrs by trypan blue exclusion assay
    		[PMID: 19093884]
    NCI-H727 IC50
    1.37 μM
    Compound: SAHA
    Cytotoxicity against human NCI-H727 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H727 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 35858522]
    NCI-H838 IC50
    5.18 μM
    Compound: Vorinostat
    Antiproliferation activity against human NCI-H838 cells incubated for 72 hrs by MTT assay
    Antiproliferation activity against human NCI-H838 cells incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    NCI-H929 IC50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H929 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human NCI-H929 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25238284]
    NCI-H929 EC50
    1.4 μM
    Compound: 3; SAHA
    Antiproliferative activity against human NCI-H929 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    Antiproliferative activity against human NCI-H929 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 31627059]
    NCI-H929 IC50
    2.83 μM
    Compound: SAHA
    Antiproliferative activity against human NCI-H929 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Antiproliferative activity against human NCI-H929 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 26890114]
    NFF IC50
    5170 nM
    Compound: SAHA
    Cytotoxicity against human NFF cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human NFF cells after 72 hrs by sulforhodamine B assay
    		[PMID: 30245402]
    NIH3T3 EC50
    4.8 μM
    Compound: SAHA
    Cytotoxicity against mouse NIH/3T3 cells assessed as cell proliferation after 70 hrs by MTS assay
    Cytotoxicity against mouse NIH/3T3 cells assessed as cell proliferation after 70 hrs by MTS assay
    		[PMID: 25974739]
    NUGC-3 GI50
    2.79 μM
    Compound: 2, SAHA
    Growth inhibition of human NUGC3 cells by SRB assay
    Growth inhibition of human NUGC3 cells by SRB assay
    		[PMID: 17904843]
    NUGC-3 GI50
    2.94 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human NUGC3 cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human NUGC3 cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    NUGC-3 GI50
    2.94 μM
    Compound: SAHA
    Growth inhibition of human NUGC3 cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human NUGC3 cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    NUGC-3 GI50
    2.94 μM
    Compound: SAHA
    Growth inhibition of human NUGC3 cells after 5 days by sulforhodamine B assay
    Growth inhibition of human NUGC3 cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    OCI-AML2 IC50
    0.78 μM
    Compound: 5; SAHA
    Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
    		[PMID: 28765013]
    OCI-AML2 IC50
    390 nM
    Compound: SAHA
    Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    OCI-AML-3 IC50
    0.85 μM
    Compound: 5; SAHA
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    		[PMID: 28765013]
    OCI-AML-3 IC50
    1365 nM
    Compound: SAHA
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    OCI-AML-3 IC50
    300 nM
    Compound: SAHA
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    OCI-Ly3 IC50
    2.2 μM
    Compound: SAHA
    Antiproliferative activity against human OCI-LY3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human OCI-LY3 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    OE19 GI50
    1.42 μM
    Compound: Vorinostat
    Antiproliferative activity against human OE19 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
    Antiproliferative activity against human OE19 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
    		[PMID: 31420257]
    OE33 GI50
    1.12 μM
    Compound: Vorinostat
    Antiproliferative activity against human OE33 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
    Antiproliferative activity against human OE33 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
    		[PMID: 31420257]
    ONS-76 IC50
    2.04 μM
    Compound: Vorinostat
    Antiproliferative activity against human ONS76 cells after 72 hrs by Celltiter-Glo assay
    Antiproliferative activity against human ONS76 cells after 72 hrs by Celltiter-Glo assay
    		[PMID: 28581289]
    OPM-2 EC50
    2.9 μM
    Compound: 3; SAHA
    Antiproliferative activity against human OPM2 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    Antiproliferative activity against human OPM2 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 31627059]
    OPM-2 IC50
    2.91 μM
    Compound: 1; SAHA
    Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo assay
    Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo assay
    		[PMID: 27541357]
    OPM-2 IC50
    2.91 μM
    Compound: 2
    Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo luminescent assay
    Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo luminescent assay
    		[PMID: 28953386]
    OVCAR-3 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
    Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    OVCAR-3 GI50
    1.4 μM
    Compound: SAHA
    Antiproliferative activity against human OVCAR3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human OVCAR3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    OVCAR-3 GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
    Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    OVCAR-4 GI50
    4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human OVCAR4 cells after 72 hrs by MTS assay
    Growth inhibition of human OVCAR4 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    OVCAR-5 GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human OVCAR5 cells after 72 hrs by MTS assay
    Growth inhibition of human OVCAR5 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    OVCAR-5 GI50
    1.78 μM
    Compound: SAHA
    Antiproliferative activity against human OVCAR5 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human OVCAR5 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 25800646]
    OVCAR-5 GI50
    1.78 μM
    Compound: 1, SAHA
    Antiproliferative activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 24119555]
    OVCAR-8 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human OVCAR8 cells after 72 hrs by MTS assay
    Growth inhibition of human OVCAR8 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    PANC-1 IC50
    > 10 μM
    Compound: SAHA
    Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    PANC-1 IC50
    0.9 μM
    Compound: Vorinostat
    Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    PANC-1 IC50
    3.14 μM
    Compound: SAHA
    Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 37116762]
    PANC-1 GI50
    678 nM
    Compound: SAHA
    Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
    		[PMID: 24999749]
    PBL IC50
    3.4 μM
    Compound: Vorinostat
    Cytotoxicity against human PBL cells assessed as cell growth inhibition after 72 hrs by MTS assay
    Cytotoxicity against human PBL cells assessed as cell growth inhibition after 72 hrs by MTS assay
    		[PMID: 30004697]
    PBMC IC50
    < 3.5 μM
    Compound: Vorinostat
    Cytotoxicity against human PBMC after 72 hrs by CellTiter-Glo luminescent cell viability assay
    Cytotoxicity against human PBMC after 72 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 30365892]
    PBMC IC50
    229 nM
    Compound: SAHA
    Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
    Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
    		10.1039/C3MD00285C
    PBMC IC50
    955 nM
    Compound: SAHA
    Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated IL-6 production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
    Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated IL-6 production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
    		10.1039/C3MD00285C
    PC-3 EC50
    > 166.67 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 23820574]
    PC-3 GI50
    > 410 nM
    Compound: Vorinostat
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    PC-3 IC50
    > 5 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    		[PMID: 29787262]
    PC-3 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    PC-3 GI50
    0.6 μM
    Compound: 1; SAHA
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 28395150]
    PC-3 GI50
    0.71 μM
    Compound: SAHA
    Growth inhibition of human PC3 cells after 21 hrs by MTT assay
    Growth inhibition of human PC3 cells after 21 hrs by MTT assay
    		[PMID: 17662606]
    PC-3 GI50
    0.73 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    		[PMID: 27344487]
    PC-3 IC50
    0.85 μM
    Compound: 2
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    		[PMID: 28953386]
    PC-3 IC50
    0.85 μM
    Compound: 1; SAHA
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    		[PMID: 27541357]
    PC-3 GI50
    0.89 μM
    Compound: 1, SAHA
    Growth inhibition of PC3 cells by SRB assay
    Growth inhibition of PC3 cells by SRB assay
    		[PMID: 17477518]
    PC-3 GI50
    0.89 μM
    Compound: 2, SAHA
    Antiproliferative activity against human PC3 cells by SRB assay
    Antiproliferative activity against human PC3 cells by SRB assay
    		[PMID: 16723227]
    PC-3 GI50
    0.96 μM
    Compound: Vorinostat
    Growth inhibition of human PC3 cells after 72 hrs by CellTiter Glo assay
    Growth inhibition of human PC3 cells after 72 hrs by CellTiter Glo assay
    		[PMID: 25182565]
    PC-3 IC50
    1 μM
    Compound: 4
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    		[PMID: 30243158]
    PC-3 GI50
    1.02 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    		[PMID: 21712146]
    PC-3 IC50
    1.14 μM
    Compound: SAHA
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    PC-3 GI50
    1.21 μM
    Compound: 1, SAHA
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    		[PMID: 22439863]
    PC-3 IC50
    1.21 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human PC3 cells after 96 hrs by celltiter 96 assay
    Antiproliferative activity against human PC3 cells after 96 hrs by celltiter 96 assay
    		[PMID: 21634430]
    PC-3 IC50
    1.33 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 21714538]
    PC-3 IC50
    1.35 μM
    Compound: Vorinostat
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    PC-3 IC50
    1.42 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    PC-3 IC50
    1.5 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by SRB assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by SRB assay
    		[PMID: 29223096]
    PC-3 IC50
    1.56 μM
    Compound: 1; SAHA
    Antiproliferative activity against human PC-3 cells incubated for 48 hrs by Sulforhodamine B staining method
    Antiproliferative activity against human PC-3 cells incubated for 48 hrs by Sulforhodamine B staining method
    		[PMID: 33077264]
    PC-3 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human PC3 cells after 72 hrs by MTS assay
    Growth inhibition of human PC3 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    PC-3 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    PC-3 IC50
    1.74 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human PC3 cells by MTT assay
    Cytotoxicity against human PC3 cells by MTT assay
    		[PMID: 24766560]
    PC-3 GI50
    1.77 μM
    Compound: 1, SAHA
    Growth inhibition of human PC3 cells after 96 hrs by MTT assay
    Growth inhibition of human PC3 cells after 96 hrs by MTT assay
    		[PMID: 26814680]
    PC-3 IC50
    1.81 μM
    Compound: SAHA
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability after 96 hrs by MTT assay
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability after 96 hrs by MTT assay
    		[PMID: 31883490]
    PC-3 IC50
    1.82 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells by colorimetric method
    Cytotoxicity against human PC3 cells by colorimetric method
    		[PMID: 32916298]
    PC-3 IC50
    1.86 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    PC-3 IC50
    1.9 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 35152694]
    PC-3 IC50
    1.92 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    PC-3 IC50
    1.98 μM
    Compound: SAHA, Vorinostat
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 21924799]
    PC-3 IC50
    10.4 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 26216016]
    PC-3 IC50
    13.91 μM
    Compound: Vorinostat
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 28371677]
    PC-3 IC50
    16.28 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 28336407]
    PC-3 GI50
    18.83 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 28629630]
    PC-3 GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human PC3 cells after 72 hrs by MTS assay
    Growth inhibition of human PC3 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    PC-3 IC50
    2.03 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells incubated for 96 hrs by resazurin assay
    Antiproliferative activity against human PC3 cells incubated for 96 hrs by resazurin assay
    		[PMID: 32435375]
    PC-3 IC50
    2.459 μM
    Compound: SAHA
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    PC-3 GI50
    2.69 μM
    Compound: 1, SAHA, Zolinza, Vorinostat
    Cytotoxicity against human PC3 cells assessed as growth inhibition by SRB assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition by SRB assay
    		[PMID: 23163332]
    PC-3 GI50
    2.69 μM
    Compound: 2, SAHA
    Growth inhibition of human PC3 cells by SRB assay
    Growth inhibition of human PC3 cells by SRB assay
    		[PMID: 17904843]
    PC-3 GI50
    2.69 μM
    Compound: SAHA
    Growth inhibition of human PC3 cells measured after 5 days by sulforhodamine-B assay
    Growth inhibition of human PC3 cells measured after 5 days by sulforhodamine-B assay
    		[PMID: 28011426]
    PC-3 GI50
    2.69 μM
    Compound: SAHA
    Growth inhibition of human PC3 cells after 5 days by sulforhodamine B assay
    Growth inhibition of human PC3 cells after 5 days by sulforhodamine B assay
    		[PMID: 25811792]
    PC-3 IC50
    2.78 μM
    Compound: 1, SAHA
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    PC-3 IC50
    2.9 μM
    Compound: Vorinostat
    Antiproliferative activity against human PC3 cells by CCK8 assay
    Antiproliferative activity against human PC3 cells by CCK8 assay
    		[PMID: 30660827]
    PC-3 IC50
    2.92 μM
    Compound: SAHA
    Anti-proliferative activity against human PC3 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 28947154]
    PC-3 GI50
    2000 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human PC3 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human PC3 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    PC-3 IC50
    3 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    PC-3 IC50
    3 μM
    Compound: 2; SAHA
    Anticancer activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Anticancer activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 34634618]
    PC-3 IC50
    3.07 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
    		[PMID: 29360358]
    PC-3 IC50
    3.2 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 31546197]
    PC-3 IC50
    3.22 μM
    Compound: SAHA
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    		[PMID: 37079967]
    PC-3 IC50
    3.46 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells incubated for 72 hrs by MTT assay
    		[PMID: 28987602]
    PC-3 IC50
    3.57 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    PC-3 IC50
    3.57 μM
    Compound: SA, SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    PC-3 IC50
    3.6 μM
    Compound: 1; SAHA
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    PC-3 IC50
    3052.4 nM
    Compound: SAHA
    Inhibition of Class 2a histone deacetylase in human PC3 cells using Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
    Inhibition of Class 2a histone deacetylase in human PC3 cells using Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
    		[PMID: 26349626]
    PC-3 IC50
    4.31 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
    		[PMID: 24185378]
    PC-3 GI50
    4.6 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    PC-3 IC50
    447.6 nM
    Compound: SAHA
    Inhibition of Class 1 histone deacetylase in human PC3 cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
    Inhibition of Class 1 histone deacetylase in human PC3 cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
    		[PMID: 26349626]
    PC-3 GI50
    5 μM
    Compound: Vorinostat
    Antiproliferative activity against human PC3 cells incubated for 72 hrs by CellTiter-Glo luminescence assay
    Antiproliferative activity against human PC3 cells incubated for 72 hrs by CellTiter-Glo luminescence assay
    		[PMID: 30802730]
    PC-3 IC50
    5.36 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    PC-3 IC50
    5.79 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 25311567]
    PC-3 IC50
    6.5 μM
    Compound: vorinostat
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by MTT assay
    		[PMID: 20403695]
    PC-3 IC50
    6.7 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 29533873]
    PC-3 IC50
    60.8 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells incubated for 24 hrs by CCK8 assay
    Antiproliferative activity against human PC3 cells incubated for 24 hrs by CCK8 assay
    		[PMID: 32247729]
    PC-3 IC50
    7.26 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 26907204]
    PC-3 IC50
    7.3 μM
    Compound: SAHA
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26149591]
    PC-3 GI50
    8.17 μM
    Compound: SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 19822426]
    PC-3 IC50
    873.26 nM
    Compound: 1; SAHA
    Antiproliferative activity against human PC3 cells measured after 48 hrs by sulforhodamine-B assay
    Antiproliferative activity against human PC3 cells measured after 48 hrs by sulforhodamine-B assay
    		[PMID: 27886544]
    PC-3 IC50
    9.79 μM
    Compound: 1, SAHA
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 24525003]
    PC-3 IC50
    9.9 μM
    Compound: 1, SAHA
    Inhibition of human PC3 cell proliferation after 48 hrs by MTT assay
    Inhibition of human PC3 cell proliferation after 48 hrs by MTT assay
    		[PMID: 23493449]
    PLC IC50
    1.534 μM
    Compound: SAHA
    Cytotoxicity against human PLC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human PLC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    PLC-PRF-5 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human PLC-PRF-5 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human PLC-PRF-5 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    PLC-PRF-5 IC50
    1.87 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human PLC-PRF-5 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human PLC-PRF-5 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    PLC-PRF-5 IC50
    2.22 μM
    Compound: SAHA
    Antiproliferative activity against human PLC-PRF-5 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human PLC-PRF-5 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    Raji IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human Raji cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human Raji cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    Raji IC50
    0.97 nM
    Compound: SAHA
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    		[PMID: 28325601]
    Raji IC50
    0.97 μM
    Compound: SAHA
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    		[PMID: 29534936]
    Raji IC50
    1.11 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    Raji IC50
    196 nM
    Compound: SAHA
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    		[PMID: 30629434]
    Raji IC50
    867.4 nM
    Compound: SAHA
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    Raji IC50
    9.44 μM
    Compound: SAHA
    Antiproliferative activity against human Raji cells after 3 days by MTT assay
    Antiproliferative activity against human Raji cells after 3 days by MTT assay
    		[PMID: 28601509]
    Ramos IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human Ramos cells after 72 hrs by MTT assay
    Cytotoxicity against human Ramos cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    Ramos IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human Ramos cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human Ramos cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    Ramos IC50
    0.52 nM
    Compound: SAHA
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    		[PMID: 28325601]
    Ramos IC50
    0.52 μM
    Compound: SAHA
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    		[PMID: 29534936]
    Ramos IC50
    0.62 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    Ramos IC50
    3.9 μM
    Compound: SAHA
    Antiproliferative activity against human Ramos cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human Ramos cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    Ramos IC50
    514.6 nM
    Compound: SAHA
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    RAW264.7 IC50
    0.76 μM
    Compound: 1, SAHA
    Inhibition of LPS-stimulated TNFalpha production in RAW264.7 cells after 24 hrs by ELISA
    Inhibition of LPS-stimulated TNFalpha production in RAW264.7 cells after 24 hrs by ELISA
    		[PMID: 17477518]
    RAW264.7 IC50
    1.88 μM
    Compound: 1, SAHA
    Inhibition of LPS-stimulated NO production in RAW264.7 cells after 24 hrs by ELISA
    Inhibition of LPS-stimulated NO production in RAW264.7 cells after 24 hrs by ELISA
    		[PMID: 17477518]
    RPMI-8226 IC50
    0.57 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
    		[PMID: 31413795]
    RPMI-8226 IC50
    0.66 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
    		[PMID: 29534936]
    RPMI-8226 IC50
    0.684 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
    Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
    		[PMID: 31865013]
    RPMI-8226 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 26890114]
    RPMI-8226 IC50
    1.25 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
    		[PMID: 28213282]
    RPMI-8226 GI50
    1.5 μM
    Compound: SAHA; NSC759852
    Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    		[PMID: 36306372]
    RPMI-8226 IC50
    10.6 μM
    Compound: SAHA
    Growth inhibition of human RPMI8226 cells after 72 hrs by MTT assay
    Growth inhibition of human RPMI8226 cells after 72 hrs by MTT assay
    		[PMID: 30594434]
    RPMI-8226 IC50
    2.39 μM
    Compound: SAHA
    Cytotoxicity against human RPMI8226 cells assessed as cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human RPMI8226 cells assessed as cell viability after 72 hrs by CCK8 assay
    		[PMID: 26211462]
    RPMI-8226 IC50
    2.39 μM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by WST8 assay
    		[PMID: 25261927]
    RPMI-8226 IC50
    2.4 μM
    Compound: SAHA
    Cytotoxicity against human RPMI8226 cells after 72 hrs by MTS assay
    Cytotoxicity against human RPMI8226 cells after 72 hrs by MTS assay
    		[PMID: 25490132]
    RPMI-8226 IC50
    423 nM
    Compound: SAHA
    Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay
    Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    RPMI-8226 IC50
    585.8 nM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
    Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    RPMI-8226 IC50
    870 nM
    Compound: SAHA
    Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    RS4-11 IC50
    3.98 μM
    Compound: SAHA
    Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34954595]
    RXF 393 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human RXF393 cells after 72 hrs by MTS assay
    Growth inhibition of human RXF393 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    RXF 393 GI50
    1.3 μM
    Compound: SAHA
    Antiproliferative activity against human RXF393 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human RXF393 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    RXF 631 GI50
    2 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human RXF631L cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human RXF631L cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    S9 IC50
    > 100 nM
    Compound: 6, SAHA
    Inhibition of human recombinant HDAC4 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of human recombinant HDAC4 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    S9 IC50
    120.5 nM
    Compound: 6, SAHA
    Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    S9 IC50
    21.5 nM
    Compound: 6, SAHA
    Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    S9 IC50
    34.5 nM
    Compound: 6, SAHA
    Inhibition of full length human recombinant HDAC11 expressed in baculovirus infected insect S9 cells after 30 mins by fluorescence assay
    Inhibition of full length human recombinant HDAC11 expressed in baculovirus infected insect S9 cells after 30 mins by fluorescence assay
    		[PMID: 25906087]
    S9 IC50
    5.5 nM
    Compound: 6, SAHA
    Inhibition of full length human recombinant HDAC8 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of full length human recombinant HDAC8 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    S9 IC50
    58.5 nM
    Compound: 6, SAHA
    Inhibition of full length human recombinant HDAC3 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
    Inhibition of full length human recombinant HDAC3 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
    		[PMID: 25906087]
    Sf21 IC50
    0.26 μM
    Compound: SAHA
    Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assay
    Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assay
    		[PMID: 26890116]
    Sf21 IC50
    0.306 μM
    Compound: 1; SAHA
    Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
    Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
    		[PMID: 27541357]
    Sf21 IC50
    1.6 μM
    Compound: SAHA
    Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf21 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf21 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    SF-268 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SF268 cells after 72 hrs by MTS assay
    Growth inhibition of human SF268 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SF-295 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SF295 cells after 72 hrs by MTS assay
    Growth inhibition of human SF295 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SF-539 GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SF539 cells after 72 hrs by MTS assay
    Growth inhibition of human SF539 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SF-539 GI50
    2 μM
    Compound: SAHA; NSC759852
    Cytotoxicity against human SF-539 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity against human SF-539 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
    		[PMID: 36306372]
    Sf9 IC50
    > 1 μM
    Compound: 1; SAHA
    Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs by electrophoretic mobility shift assay
    Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs by electrophoretic mobility shift assay
    		[PMID: 31938464]
    Sf9 IC50
    > 1000 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
    Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
    		[PMID: 30629434]
    Sf9 IC50
    > 10000 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    > 10000 nM
    Compound: SAHA
    Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    > 10000 nM
    Compound: SAHA
    Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    > 10000 nM
    Compound: SAHA
    Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    > 10000 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    0.0058 μM
    Compound: 1; SAHA
    Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by electrophoretic mobility shift assay
    Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by electrophoretic mobility shift assay
    		[PMID: 31938464]
    Sf9 IC50
    0.00657 μM
    Compound: 1; SAHA
    Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by electrophoretic mobility shift assay
    Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by electrophoretic mobility shift assay
    		[PMID: 31938464]
    Sf9 IC50
    0.0097 μM
    Compound: Vorinostat
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 9
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 9
    		[PMID: 31762274]
    Sf9 IC50
    0.02 μM
    Compound: 1; SAHA
    Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
    Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
    		[PMID: 27541357]
    Sf9 IC50
    0.029 μM
    Compound: SAHA
    Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate incubated for 90 mins by fluorescence assay
    Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate incubated for 90 mins by fluorescence assay
    		[PMID: 26890116]
    Sf9 IC50
    0.032 μM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC6 expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
    Inhibition of recombinant full length human HDAC6 expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
    		10.1039/C4MD00203B
    Sf9 IC50
    0.038 μM
    Compound: Vorinostat
    Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    		[PMID: 31420257]
    Sf9 IC50
    0.051 μM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC1 (1 to 482 amino acids) expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
    Inhibition of recombinant full length human HDAC1 (1 to 482 amino acids) expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
    		10.1039/C4MD00203B
    Sf9 IC50
    0.081 μM
    Compound: SAHA
    Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
    Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
    		[PMID: 26907204]
    Sf9 IC50
    0.089 μM
    Compound: Vorinostat
    Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    		[PMID: 31420257]
    Sf9 IC50
    0.102 μM
    Compound: Vorinostat
    Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 mins by fluorescence assay
    Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 mins by fluorescence assay
    		[PMID: 31762274]
    Sf9 IC50
    0.105 μM
    Compound: Vorinostat
    Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric m
    Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric m
    		[PMID: 31420257]
    Sf9 IC50
    0.111 μM
    Compound: Vorinostat
    Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate incubated for 90 mins by fluorescence assay
    Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate incubated for 90 mins by fluorescence assay
    		[PMID: 31762274]
    Sf9 IC50
    0.146 μM
    Compound: Vorinostat
    Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
    Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
    		[PMID: 31762274]
    Sf9 IC50
    0.183 μM
    Compound: Vorinostat
    Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
    		[PMID: 31420257]
    Sf9 IC50
    0.23 μM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC8 expressed in Baculovirus infected insect Sf9 cells preincubated for 30 mins followed by substrate addition measured after 15 to 45 mins by luminescence assay
    Inhibition of recombinant full length human HDAC8 expressed in Baculovirus infected insect Sf9 cells preincubated for 30 mins followed by substrate addition measured after 15 to 45 mins by luminescence assay
    		10.1039/C4MD00203B
    Sf9 IC50
    0.497 μM
    Compound: 1; SAHA
    Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by electrophoretic mobility shift assay
    Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by electrophoretic mobility shift assay
    		[PMID: 31938464]
    Sf9 IC50
    0.78 μM
    Compound: SAHA
    Inhibition of recombinant full-length human C-terminal HDAC8 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    Inhibition of recombinant full-length human C-terminal HDAC8 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    Sf9 IC50
    0.8 μM
    Compound: SAHA
    Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    Sf9 IC50
    101 nM
    Compound: Vorinostat
    Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based a
    Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based a
    		[PMID: 31391882]
    Sf9 IC50
    102 nM
    Compound: Zolinza
    Inhibition of full length recombinant GST-tagged N-terminal human HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
    Inhibition of full length recombinant GST-tagged N-terminal human HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
    		[PMID: 31531206]
    Sf9 IC50
    11 nM
    Compound: SAHA
    Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AMC preincubated for 15 mins followed by substrate addition measured a
    Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AMC preincubated for 15 mins followed by substrate addition measured a
    		[PMID: 27186676]
    Sf9 IC50
    13 nM
    Compound: SAHA
    Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
    Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
    		[PMID: 30594434]
    Sf9 IC50
    144.7 nM
    Compound: SAHA; Vor
    Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr fo
    Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr fo
    		[PMID: 32321249]
    Sf9 IC50
    170 nM
    Compound: SAHA
    Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
    Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
    		[PMID: 30629434]
    Sf9 IC50
    174 nM
    Compound: SAHA
    Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    		[PMID: 25815139]
    Sf9 IC50
    19 nM
    Compound: SAHA
    Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence b
    Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence b
    		[PMID: 31505452]
    Sf9 IC50
    208 nM
    Compound: SAHA
    Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    23 nM
    Compound: SAHA
    Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    		[PMID: 25815139]
    Sf9 IC50
    23 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    		[PMID: 25815139]
    Sf9 IC50
    29 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    3.7 μM
    Compound: SAHA
    Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
    Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
    		[PMID: 26907204]
    Sf9 IC50
    32 nM
    Compound: 5; SAHA
    Inhibition of recombinant C-terminal His/FLAG-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr
    Inhibition of recombinant C-terminal His/FLAG-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr
    		[PMID: 31117517]
    Sf9 IC50
    328 nM
    Compound: SAHA
    Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 240 mins by fluorescence based assay
    Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 240 mins by fluorescence based assay
    		[PMID: 31505452]
    Sf9 IC50
    33 nM
    Compound: SAHA
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    34.3 nM
    Compound: Vorinostat
    Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
    Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
    		[PMID: 31391882]
    Sf9 IC50
    35 nM
    Compound: SAHA
    Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
    Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
    		[PMID: 30594434]
    Sf9 IC50
    370 nM
    Compound: SAHA
    Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay
    Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay
    		[PMID: 27055940]
    Sf9 IC50
    47 nM
    Compound: Zolinza
    Inhibition of full length recombinant FLAG/His-tagged C-terminal human HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
    Inhibition of full length recombinant FLAG/His-tagged C-terminal human HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
    		[PMID: 31531206]
    Sf9 IC50
    49 nM
    Compound: SAHA
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed b
    Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed b
    		[PMID: 31505452]
    Sf9 IC50
    51 nM
    Compound: SAHA
    Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
    Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
    		[PMID: 31505452]
    Sf9 IC50
    56 nM
    Compound: SAHA
    Inhibition of recombinant C-terminal His-tagged full length human HDAC3/NcoR2 complex expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    Inhibition of recombinant C-terminal His-tagged full length human HDAC3/NcoR2 complex expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
    		[PMID: 25815139]
    Sf9 IC50
    682 nM
    Compound: SAHA
    Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
    		[PMID: 31177073]
    Sf9 IC50
    8.7 μM
    Compound: SAHA
    Inhibition of recombinant full-length human HDAC11 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    Inhibition of recombinant full-length human HDAC11 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
    		[PMID: 30245394]
    Sf9 IC50
    8.8 nM
    Compound: SAHA
    Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC class 2a substrate after 30 mins by fluorescence assay
    Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC class 2a substrate after 30 mins by fluorescence assay
    		[PMID: 25815139]
    SGC-7901 IC50
    0.64 μM
    Compound: 1; SAHA
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
    		[PMID: 34656899]
    SGC-7901 IC50
    1.03 μM
    Compound: SAHA
    Antiproliferative activity against human SGC7901 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    		[PMID: 31400938]
    SGC-7901 IC50
    135.71 μM
    Compound: SAHA
    Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    SGC-7901 IC50
    2.12 μM
    Compound: SAHA
    Antiproliferative activity against human SGC-7901 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human SGC-7901 cells measured after 48 hrs by MTT assay
    		[PMID: 35041998]
    SGC-7901 IC50
    3.3 μM
    Compound: Vorinostat
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
    		[PMID: 35608269]
    SH-SY5Y EC50
    > 50 μM
    Compound: SAHA
    Antiproliferative activity against human SH-SY5Y cells after 24 hrs by XTT assay
    Antiproliferative activity against human SH-SY5Y cells after 24 hrs by XTT assay
    		[PMID: 21548582]
    SH-SY5Y IC50
    0.5 μM
    Compound: SAHA
    Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assay
    Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assay
    		[PMID: 19344175]
    SH-SY5Y IC50
    0.73 μM
    Compound: SAHA
    Antiproliferative activity against human SH-SY5Y cells harboring ALK F1174L mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human SH-SY5Y cells harboring ALK F1174L mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
    		[PMID: 34237620]
    SH-SY5Y EC50
    17.4 μM
    Compound: SAHA
    Antiproliferative activity against human SH-SY5Y cells after 72 hrs by XTT assay
    Antiproliferative activity against human SH-SY5Y cells after 72 hrs by XTT assay
    		[PMID: 21548582]
    SH-SY5Y IC50
    2 μM
    Compound: SAHA
    Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 19344175]
    SH-SY5Y EC50
    25.6 μM
    Compound: SAHA
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by XTT assay
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by XTT assay
    		[PMID: 21548582]
    SH-SY5Y IC50
    7.87 μM
    Compound: SAHA
    Cytotoxicity against human SH-SY5Y cells assessed as cell viability measured after 36 hrs by CCK8 assay
    Cytotoxicity against human SH-SY5Y cells assessed as cell viability measured after 36 hrs by CCK8 assay
    		[PMID: 36645952]
    SK-BR-3 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human SKBR3 cells after 72 hrs by MTT assay
    Cytotoxicity against human SKBR3 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    SK-BR-3 IC50
    1.19 μM
    Compound: SAHA
    Antiproliferative activity against human SK-BR-3 cells after hrs by ATP content assay
    Antiproliferative activity against human SK-BR-3 cells after hrs by ATP content assay
    		[PMID: 20143778]
    SK-BR-3 GI50
    1.2 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human SK-BR-3 cells after 72 hrs by WST1 assay
    Cytotoxicity against human SK-BR-3 cells after 72 hrs by WST1 assay
    		[PMID: 24015327]
    SK-BR-3 EC50
    2.1 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human SK-BR-3 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human SK-BR-3 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    SK-BR-3 IC50
    2.13 μM
    Compound: Vorinostat
    Antiproliferation activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay
    Antiproliferation activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay
    		[PMID: 33493830]
    SK-BR-3 IC50
    2.58 μM
    Compound: 8
    Antiproliferative activity against human SK-BR-3 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Antiproliferative activity against human SK-BR-3 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
    		[PMID: 27769671]
    SK-BR-3 IC50
    2.6 μM
    Compound: 2a
    Cytotoxicity against human SKBR3 cells overexpressing HER2 by resazurin dye reduction assay
    Cytotoxicity against human SKBR3 cells overexpressing HER2 by resazurin dye reduction assay
    		[PMID: 21080629]
    SK-HEP1 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human SK-HEP1 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human SK-HEP1 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    SK-HEP1 IC50
    1.85 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human SK-HEP1 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human SK-HEP1 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    SK-HEP1 IC50
    3.3 μM
    Compound: 2; SAHA
    Anticancer activity against human SK-HEP1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Anticancer activity against human SK-HEP1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 34634618]
    SK-HEP1 IC50
    3.46 μM
    Compound: SAHA
    Antiproliferative activity against human SKHEP1 cells after hrs by ATP content assay
    Antiproliferative activity against human SKHEP1 cells after hrs by ATP content assay
    		[PMID: 20143778]
    SK-HEP1 IC50
    36.93 μM
    Compound: SAHA
    Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    SK-MEL-2 GI50
    1.3 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SK-MEL-2 cells after 72 hrs by MTS assay
    Growth inhibition of human SK-MEL-2 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SK-MEL-28 IC50
    0.482 μM
    Compound: 1; SAHA
    Antiproliferative activity against human SK-MEL-28 cells after 72 hrs by resazurin dye based fluorescence assay
    Antiproliferative activity against human SK-MEL-28 cells after 72 hrs by resazurin dye based fluorescence assay
    		[PMID: 29456804]
    SK-MEL-28 GI50
    1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTS assay
    Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SK-MEL-5 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SK-MEL-5 cells after 72 hrs by MTS assay
    Growth inhibition of human SK-MEL-5 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SK-MES-1 IC50
    2.42 μM
    Compound: SAHA
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    SK-MES-1 EC50
    2.42 μM
    Compound: SAHA
    Cytotoxicity against human SKMES1 cells after 72 hrs by trypan blue exclusion assay
    Cytotoxicity against human SKMES1 cells after 72 hrs by trypan blue exclusion assay
    		[PMID: 19093884]
    SK-N-AS IC50
    0.7 μM
    Compound: Vorinostat
    Antiproliferative activity against human SK-N-AS cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    Antiproliferative activity against human SK-N-AS cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
    		[PMID: 31391882]
    SK-N-BE(2) IC50
    4.58 μM
    Compound: SAHA
    Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    		[PMID: 37079967]
    SK-OV-3 IC50
    > 1000 nM
    Compound: SAHA
    Cytotoxicity against human SKOV3 cells after 72 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    SK-OV-3 GI50
    1 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SKOV3 cells after 72 hrs by MTS assay
    Growth inhibition of human SKOV3 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SK-OV-3 IC50
    1.66 mM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
    		[PMID: 20171895]
    SK-OV-3 IC50
    1130 nM
    Compound: SAHA
    Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
    		[PMID: 31177073]
    SK-OV-3 IC50
    2.2 μM
    Compound: 2a
    Cytotoxicity against human SKOV3 cells overexpressing HER2 by resazurin dye reduction assay
    Cytotoxicity against human SKOV3 cells overexpressing HER2 by resazurin dye reduction assay
    		[PMID: 21080629]
    SK-OV-3 GI50
    2.5 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    SMMC-7721 IC50
    1.99 μM
    Compound: SAHA
    Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    SMMC-7721 IC50
    5.2 μM
    Compound: SAHA
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    		[PMID: 31120744]
    SMMC-7721 IC50
    5.23 μM
    Compound: SAHA
    Antiproliferative activity against human SMMC7721 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells incubated for 48 hrs by MTT assay
    		[PMID: 30851694]
    SMMC-7721 IC50
    5.274 μM
    Compound: SAHA
    Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
    		[PMID: 31991336]
    SMMC-7721 IC50
    5.46 μM
    Compound: 1; CTCL
    Cytotoxicity against human SMMC-7721 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human SMMC-7721 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    		[PMID: 33143937]
    SMMC-7721 IC50
    5.46 μM
    Compound: Vorinostat
    Cytotoxicity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    SMMC-7721 IC50
    5.61 μM
    Compound: SAHA
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    		[PMID: 30108831]
    SMMC-7721 IC50
    5.61 μM
    Compound: SAHA
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    		[PMID: 29288941]
    SN12C GI50
    2 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SN12C cells after 72 hrs by MTS assay
    Growth inhibition of human SN12C cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SNB-19 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SNB19 cells after 72 hrs by MTS assay
    Growth inhibition of human SNB19 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SNB-75 GI50
    0.79 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SNB75 cells after 72 hrs by MTS assay
    Growth inhibition of human SNB75 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SNB-75 GI50
    0.8 μM
    Compound: SAHA
    Antiproliferative activity against human SNB75 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human SNB75 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    SNB-78 GI50
    16 μM
    Compound: 2, (SAHA, vorinostat)
    Growth inhibition of human SNB78 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SNB78 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 19419205]
    SNU-16 IC50
    0.29 μM
    Compound: 3; SAHA
    Antiproliferative activity against human SNU-16 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SNU-16 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 36449947]
    SNU-387 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human SNU-387 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human SNU-387 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    SNU-387 IC50
    2.45 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human SNU-387 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human SNU-387 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    SNU-398 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human SNU-398 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human SNU-398 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    SNU-398 IC50
    1.39 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human SNU-398 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human SNU-398 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    SNU-423 IC50
    0.079 μM
    Compound: SAHA
    Antiproliferative activity against human SNU-423 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human SNU-423 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 34509167]
    SR GI50
    0.4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SR cells after 72 hrs by MTS assay
    Growth inhibition of human SR cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SR GI50
    0.4 μM
    Compound: SAHA
    Antiproliferative activity against human SR cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human SR cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    SU.86.86 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human SU.86.86 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SU.86.86 cells after 72 hrs by MTT assay
    		[PMID: 18642892]
    SU.86.86 IC50
    1 μM
    Compound: SAHA
    Antiproliferative activity against human SU-8686 cells by MTT assay
    Antiproliferative activity against human SU-8686 cells by MTT assay
    		[PMID: 19419863]
    SU.86.86 IC50
    1.3 μM
    Compound: 1a, SAHA
    Growth inhibition of human SU-8686 cells after 72 hrs by MTS assay
    Growth inhibition of human SU-8686 cells after 72 hrs by MTS assay
    		[PMID: 20055418]
    SU.86.86 IC50
    1.3 μM
    Compound: SAHA
    Cytotoxicity against human SU 86.86 cells after 72 hrs by MTT assay
    Cytotoxicity against human SU 86.86 cells after 72 hrs by MTT assay
    		[PMID: 18494463]
    SU-DHL10 IC50
    0.47 μM
    Compound: 1; SAHA
    Antiproliferative activity against human SU-DHL-10 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human SU-DHL-10 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36153841]
    SU-DHL-6 IC50
    0.43 μM
    Compound: Vorinostat
    Cytotoxicity against human SU-DHL-6 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human SU-DHL-6 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    SU-DHL-6 IC50
    0.58 μM
    Compound: Vor; SAHA
    Antiproliferative activity against human SU-DHL-6 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    Antiproliferative activity against human SU-DHL-6 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
    		[PMID: 29360358]
    SUM-159-PT IC50
    1.381 μM
    Compound: SAHA
    Cytotoxicity against human SUM159PT cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human SUM159PT cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    SW1990 IC50
    3.8 μM
    Compound: 5; SAHA
    Antiproliferative activity against human SW1990 cells after 96 hrs by MTT assay
    Antiproliferative activity against human SW1990 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    SW1990 IC50
    5.72 μM
    Compound: SAHA
    Antiproliferative activity against human SW1990 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    Antiproliferative activity against human SW1990 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
    		[PMID: 36097406]
    SW480 IC50
    2.12 μM
    Compound: SAHA
    Antiproliferative activity against human SW480 cells measured after 72 hrs
    Antiproliferative activity against human SW480 cells measured after 72 hrs
    		[PMID: 35697181]
    SW480 IC50
    3.97 μM
    Compound: SAHA
    Antiproliferative activity against human SW480 cells assessed as cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human SW480 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26555243]
    SW-620 GI50
    0.54 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human SW620 cells after 48 hrs by SRB assay
    Cytotoxicity against human SW620 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    SW-620 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SW620 cells after 72 hrs by MTS assay
    Growth inhibition of human SW620 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SW-620 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human SW620 cells after 72 hrs by MTS assay
    Growth inhibition of human SW620 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    SW-620 IC50
    1.12 μM
    Compound: SAHA
    Cytotoxicity against human SW620 cells by colorimetric method
    Cytotoxicity against human SW620 cells by colorimetric method
    		[PMID: 32916298]
    SW-620 IC50
    1.7 μM
    Compound: SAHA; 112
    Antiproliferative activity against human SW620 cells assessed as inhibition of cell proliferation by CCK-8 assay
    Antiproliferative activity against human SW620 cells assessed as inhibition of cell proliferation by CCK-8 assay
    		[PMID: 31881454]
    SW-620 IC50
    2.8 μM
    Compound: Vorinostat
    Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by MTT assay
    		[PMID: 32791404]
    SW-620 IC50
    3.2 μM
    Compound: SAHA
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 31546197]
    SW-620 IC50
    3.7 μM
    Compound: SAHA, Vorinostat, Zolinza
    Antiproliferative activity against human SW620 cells after 48 hrs by SRB assay
    Antiproliferative activity against human SW620 cells after 48 hrs by SRB assay
    		[PMID: 24185378]
    SW-620 IC50
    3.87 μM
    Compound: SAHA
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    		[PMID: 28987602]
    SW-620 IC50
    4.31 μM
    Compound: Vorinostat
    Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by SRB assay
    Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by SRB assay
    		[PMID: 32791404]
    SW-620 IC50
    4.32 μM
    Compound: SAHA
    Antiproliferative activity against human SW620 cells assessed as cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human SW620 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26555243]
    SW-620 IC50
    6.94 μM
    Compound: SAHA
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
    		[PMID: 32153186]
    T-24 EC50
    0.12 μM
    Compound: SAHA, Zolinza
    Induction of histone H3 acetylation in human T24 cells after 3 hrs by ELISA
    Induction of histone H3 acetylation in human T24 cells after 3 hrs by ELISA
    		[PMID: 19084395]
    T-24 EC50
    0.25 μM
    Compound: SAHA, Zolinza
    Induction of alpha tubulin acetylation in human T24 cells after 3 hrs by ELISA
    Induction of alpha tubulin acetylation in human T24 cells after 3 hrs by ELISA
    		[PMID: 19084395]
    T-24 IC50
    2.4 μM
    Compound: SAHA
    Antiproliferative activity against human T24 cells after 72 hrs by CellTiter blue-reagent based assay
    Antiproliferative activity against human T24 cells after 72 hrs by CellTiter blue-reagent based assay
    		[PMID: 30645113]
    T47D GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human T47D cells after 72 hrs by MTS assay
    Growth inhibition of human T47D cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    T47D GI50
    0.5 μM
    Compound: SAHA
    Antiproliferative activity against human T47D cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human T47D cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    T47D IC50
    1.25 μM
    Compound: SAHA
    Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
    Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    T47D IC50
    2.243 μM
    Compound: SAHA
    Cytotoxicity against human T47D cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human T47D cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 32823005]
    T47D IC50
    3.01 μM
    Compound: Vorinostat
    Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    		[PMID: 29518312]
    TAMH IC50
    7.86 μM
    Compound: 2
    Cytotoxicity against TAMH cells assessed as cell viability after 24 hrs by CellTiter-Glo assay
    Cytotoxicity against TAMH cells assessed as cell viability after 24 hrs by CellTiter-Glo assay
    		[PMID: 28953386]
    TAMH IC50
    7.86 μM
    Compound: 1; SAHA
    Antiproliferative activity against mouse TAMH cells after 24 hrs by CellTiter-Glo assay
    Antiproliferative activity against mouse TAMH cells after 24 hrs by CellTiter-Glo assay
    		[PMID: 27541357]
    T-cell EC50
    0.6 μM
    Compound: SAHA, Vorinostat
    Reactivation of latent HIV1 NL4-3-Luc expression in human naive CD4+ T cells treated 7 days post-infection measured after 48 hrs by luminescence plate reader analysis
    Reactivation of latent HIV1 NL4-3-Luc expression in human naive CD4+ T cells treated 7 days post-infection measured after 48 hrs by luminescence plate reader analysis
    		[PMID: 24495105]
    THP-1 IC50
    > 10 μg/mL
    Compound: SAHA
    Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay
    Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay
    		[PMID: 25240614]
    THP-1 IC50
    0.5 μg/mL
    Compound: SAHA
    Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay
    Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay
    		[PMID: 25240614]
    THP-1 IC50
    1.1 μM
    Compound: SAHA
    Cytotoxicity against human THP1 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human THP1 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28368585]
    THP-1 IC50
    3.9 μM
    Compound: SAHA
    Antiproliferative activity against human THP-1 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human THP-1 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    THP-1 IC50
    9.5 μM
    Compound: 5; SAHA
    Antiproliferative activity against human THP1 cells after 96 hrs by MTT assay
    Antiproliferative activity against human THP1 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    TK-10 GI50
    0.63 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human TK10 cells after 72 hrs by MTS assay
    Growth inhibition of human TK10 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    TSGH IC50
    2.09 μM
    Compound: 1, SAHA, Vorinostat
    Cytotoxicity against human TSGH cells by MTT assay
    Cytotoxicity against human TSGH cells by MTT assay
    		[PMID: 24766560]
    U-251 IC50
    1 μM
    Compound: Vorinostat
    Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
    		[PMID: 30660827]
    U-251 GI50
    1.53 μM
    Compound: Zolinza, NSC 701852
    Cytotoxicity against human U251 cells after 48 hrs by SRB assay
    Cytotoxicity against human U251 cells after 48 hrs by SRB assay
    		[PMID: 24015327]
    U-251 GI50
    1.6 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human U251 cells after 72 hrs by MTS assay
    Growth inhibition of human U251 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    U-251 GI50
    1.6 μM
    Compound: SAHA
    Antiproliferative activity against human U251 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    Antiproliferative activity against human U251 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
    		[PMID: 32212730]
    U-251 IC50
    17.87 μM
    Compound: 1; SAHA
    Cytotoxicity against human TMZ-sensitive U251 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human TMZ-sensitive U251 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    		[PMID: 35005974]
    U-251 GI50
    2 μM
    Compound: SAHA
    Cytotoxicity against human U251 cells by MTT assay
    Cytotoxicity against human U251 cells by MTT assay
    		[PMID: 23538115]
    U-251 GI50
    6.5 μM
    Compound: SAHA
    Cytotoxicity against human U251 cells after 48 hrs by MTT assay
    Cytotoxicity against human U251 cells after 48 hrs by MTT assay
    		[PMID: 20605448]
    U-266 IC50
    0.59 μM
    Compound: SAHA
    Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
    Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
    		[PMID: 31865013]
    U-266 IC50
    0.88 μM
    Compound: SAHA
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    		[PMID: 28757101]
    U-266 IC50
    1.09 μM
    Compound: SAHA
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    U-266 IC50
    1.35 μM
    Compound: SAHA
    Cytotoxicity against human U266 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human U266 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    U-266 IC50
    3070 nM
    Compound: SAHA
    Antiproliferative activity against human U266 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human U266 cells incubated for 48 hrs by MTT assay
    		[PMID: 32267687]
    U-266 IC50
    42.6 μM
    Compound: SAHA
    Growth inhibition of human U266 cells after 72 hrs by MTT assay
    Growth inhibition of human U266 cells after 72 hrs by MTT assay
    		[PMID: 30594434]
    U-266 IC50
    581 nM
    Compound: SAHA
    Cytotoxicity against human U266 cells after 72 hrs by MTT assay
    Cytotoxicity against human U266 cells after 72 hrs by MTT assay
    		[PMID: 26443078]
    U2932 IC50
    1.1 μM
    Compound: SAHA
    Antiproliferative activity against human U2932 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human U2932 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    U2932 IC50
    2.7 μM
    Compound: SAHA
    Antiproliferative activity against human U2932 cells after 72 hrs by MTT assay
    Antiproliferative activity against human U2932 cells after 72 hrs by MTT assay
    		[PMID: 29150335]
    U2OS IC50
    2.23 μM
    Compound: SAHA
    Anticancer activity against human U2OS cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    Anticancer activity against human U2OS cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
    		[PMID: 36244186]
    U2OS IC50
    5.7 μM
    Compound: Vorinostat
    Cytotoxicity against human U2OS cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Cytotoxicity against human U2OS cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    		[PMID: 32791404]
    U-87MG ATCC IC50
    10 μM
    Compound: 5; SAHA
    Antiproliferative activity against human U87 cells after 96 hrs by MTT assay
    Antiproliferative activity against human U87 cells after 96 hrs by MTT assay
    		[PMID: 31117517]
    U-87MG ATCC IC50
    15.71 μM
    Compound: 1; SAHA
    Antiproliferation activity against human U-87 MG cells assessed as growth inhibition measured after 1 hr by MTT assay
    Antiproliferation activity against human U-87 MG cells assessed as growth inhibition measured after 1 hr by MTT assay
    		[PMID: 33744690]
    U-87MG ATCC IC50
    52 μM
    Compound: SAHA
    Antiproliferative activity against human U-87 MG cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human U-87 MG cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    U-937 IC50
    0.37 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 26100440]
    U-937 IC50
    0.54 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
    		[PMID: 28601509]
    U-937 IC50
    0.54 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
    		[PMID: 28419930]
    U-937 IC50
    0.72 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 29954683]
    U-937 CC50
    0.78 μM
    Compound: Vorinostat
    Cytotoxicity against human U937 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Glo luminescent cell viability assay
    Cytotoxicity against human U937 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Glo luminescent cell viability assay
    		[PMID: 29541372]
    U-937 EC50
    0.82 μM
    Compound: 1a, SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by cell titer-glo assay
    Antiproliferative activity against human U937 cells after 48 hrs by cell titer-glo assay
    		[PMID: 20218673]
    U-937 EC50
    0.88 μM
    Compound: SAHA
    Cytotoxicity against human U937 cells assessed as decrease in cell viability after 44 hrs by MTT assay
    Cytotoxicity against human U937 cells assessed as decrease in cell viability after 44 hrs by MTT assay
    		[PMID: 29150330]
    U-937 EC50
    0.88 μM
    Compound: SAHA
    Growth inhibition of human U937 cells after 44 hrs by MTT assay
    Growth inhibition of human U937 cells after 44 hrs by MTT assay
    		[PMID: 28337317]
    U-937 IC50
    0.97 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 25462271]
    U-937 IC50
    1.235 μM
    Compound: SAHA
    Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
    Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
    		[PMID: 34454126]
    U-937 GI50
    1.42 μM
    Compound: vorinostat, SAHA
    Antiproliferative activity against human U937 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    Antiproliferative activity against human U937 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
    		[PMID: 25218912]
    U-937 IC50
    1.45 μM
    Compound: SA, SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 24694055]
    U-937 IC50
    1.53 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 30879863]
    U-937 IC50
    1.53 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 29500131]
    U-937 IC50
    1.64 μM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    		[PMID: 28757101]
    U-937 CC50
    1050 nM
    Compound: 1
    Antiproliferative activity against human U937 cells after 72 hrs by celltiter-blue cell viability assay
    Antiproliferative activity against human U937 cells after 72 hrs by celltiter-blue cell viability assay
    		[PMID: 19441846]
    U-937 GI50
    1460 nM
    Compound: SAHA
    Antiproliferative activity against human U937 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human U937 cells after 72 hrs by CCK8 assay
    		[PMID: 26331334]
    U-937 IC50
    2.3 μM
    Compound: 1, SAHA
    Inhibition of human U937 cell proliferation after 48 hrs by MTT assay
    Inhibition of human U937 cell proliferation after 48 hrs by MTT assay
    		[PMID: 23493449]
    U-937 IC50
    2.83 μM
    Compound: Vorinostat
    Antiproliferative activity against human U937 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human U937 cells incubated for 72 hrs by MTT assay
    		[PMID: 25953722]
    U-937 IC50
    2.83 μM
    Compound: SAHA, Zolinza
    Antiproliferative activity against human U937 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    Antiproliferative activity against human U937 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
    		[PMID: 25874326]
    U-937 IC50
    3.35 μM
    Compound: SAHA
    Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 26349626]
    U-937 GI50
    390 nM
    Compound: SAHA
    Growth inhibition of human U937 cells after 72 hrs by SRB assay
    Growth inhibition of human U937 cells after 72 hrs by SRB assay
    		[PMID: 20884208]
    U-937 IC50
    4.33 μM
    Compound: SAHA
    Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		10.1039/C4MD00203B
    U-937 IC50
    4.82 μM
    Compound: 1, SAHA
    Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    		[PMID: 26122774]
    U-937 GI50
    450 nM
    Compound: SAHA, vorinostat
    Antiproliferative activity against human U937 cells after 72 hrs by WST-1 assay
    Antiproliferative activity against human U937 cells after 72 hrs by WST-1 assay
    		[PMID: 21080647]
    U-937 IC50
    5.49 μM
    Compound: 6, SAHA
    Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 25906087]
    U-937 IC50
    907.5 nM
    Compound: SAHA
    Antiproliferative activity against p53 null human U937 cells after 72 hrs by MTT assay
    Antiproliferative activity against p53 null human U937 cells after 72 hrs by MTT assay
    		[PMID: 27505848]
    UACC-257 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human UACC257 cells after 72 hrs by MTS assay
    Growth inhibition of human UACC257 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    UACC-62 GI50
    0.4 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human UACC62 cells after 72 hrs by MTS assay
    Growth inhibition of human UACC62 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    UO-31 GI50
    0.5 μM
    Compound: SAHA, Zolinza
    Growth inhibition of human UO31 cells after 72 hrs by MTS assay
    Growth inhibition of human UO31 cells after 72 hrs by MTS assay
    		[PMID: 22435669]
    Vero IC50
    0.9 μM
    Compound: SAHA, vorinostat
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 72 hrs by MTT assay
    		[PMID: 23786452]
    Vero IC50
    1.03 μM
    Compound: SAHA
    Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 28057407]
    Vero IC50
    1.375 μg/mL
    Compound: SAHA
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    		[PMID: 20669972]
    Vero IC50
    1200 ng/mL
    Compound: SAHA
    Cytotoxicity against african green monkey Vero cells after 1 to 2 days by neutral red assay
    Cytotoxicity against african green monkey Vero cells after 1 to 2 days by neutral red assay
    		[PMID: 19914074]
    Vero IC50
    261.6 ng/mL
    Compound: SAHA
    Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
    Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
    		[PMID: 19914074]
    Vero IC50
    4.1 μM
    Compound: SAHA
    Antiproliferative activity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 33965842]
    Vero IC50
    4.1 μM
    Compound: SAHA
    Antiproliferative activity against african green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    Antiproliferative activity against african green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTT assay
    		[PMID: 25993269]
    Vero IC50
    4.465 μM
    Compound: SAHA
    Cytotoxicity against African Green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    Cytotoxicity against African Green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTS assay
    		[PMID: 32061484]
    Vero IC50
    478.9 ng/mL
    Compound: SAHA
    Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
    Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
    		[PMID: 19914074]
    Vero EC50
    5.2 μM
    Compound: SAHA
    Cytotoxicity against african green monkey Vero cells cells assessed as cell proliferation after 70 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells cells assessed as cell proliferation after 70 hrs by MTS assay
    		[PMID: 25974739]
    WI-38 IC50
    > 30 μM
    Compound: SAHA; NSC759852
    Cytotoxicity against human WI-38 cells assessed as reduction in cell survival incubated for 30 mins by methylene blue staining based analysis
    Cytotoxicity against human WI-38 cells assessed as reduction in cell survival incubated for 30 mins by methylene blue staining based analysis
    		[PMID: 36306372]
    WI-38 IC50
    10.07 μM
    Compound: 1; SAHA
    Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
    		[PMID: 36242988]
    WI-38 IC50
    49.87 μM
    Compound: SAHA
    Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 34628244]
    WI-38 GI50
    6080 nM
    Compound: SAHA
    Antiproliferative activity against human WI38 cells after 72 hrs by CCK8 assay
    Antiproliferative activity against human WI38 cells after 72 hrs by CCK8 assay
    		[PMID: 26331334]
    Z-138 IC50
    0.7 μM
    Compound: SAHA
    Antiproliferative activity against human Z138 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    Antiproliferative activity against human Z138 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
    		[PMID: 34772529]
    In Vitro

    Vorinostat efficiently suppresses MES-SA cell growth at a low dosage (3 μM) already after 24 hours treatment. HDACs class I (HDAC2 and 3) as well as class II (HDAC7) are preferentially affected by this treatment. Vorinostat significantly increases p21WAF1 expression and apoptosis in MES-SA cells[1].
    Vorinostat inhibits SK-N-SH and SK-N-Be(2)C with the IC25 values of 1 μM and 0.5 μM, respectively[2].
    Vorinostat is an effective inhibitor of HPV-18 DNA amplification, reduces oncoproteins E6 and E7 activities and triggers apoptosis in HPV-infected, differentiated cells[7].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Vorinostat Related Antibodies
    In Vivo

    Vorinostat (50 mg/kg/day) reduces tumor growth by more than 50% in nude mice injected with 5×106 MES-SA cells[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Klinische Studie
    Molekulargewicht

    264.32

    Formel

    C14H20N2O3
    CAS. Nr.

    149647-78-9
    Appearance

    Solid

    Color

    White to light yellow

    SMILES

    O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O
    Versand

    Room temperature in continental US; may vary elsewhere.
    Speicherung
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 1 year
    -20°C 6 months
    Lösungsmittel & Löslichkeit
    In Vitro: 

    DMSO : ≥ 100 mg/mL (378.33 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.7833 mL 18.9165 mL 37.8329 mL
    5 mM 0.7567 mL 3.7833 mL 7.5666 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    • Molaritätsrechner

    • Verdünnungsrechner

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  5% DMSO    40% PEG300    5% Tween-80    50% Saline

      Solubility: ≥ 2.5 mg/mL (9.46 mM); Clear solution

    • Protocol 2

      Add each solvent one by one:  5% DMSO    95% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.5 mg/mL (9.46 mM); Clear solution

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  20% HP-β-CD in Saline

      Solubility: 3.33 mg/mL (12.60 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    % 
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    Reinheit & Dokumentation

    Purity: 99.95%

    SDS (419 KB)

    COA (243 KB) LCMS (94 KB)

    Handling Instructions (2659 KB)
    Verweise

    • [1]. Hrzenjak A et al. Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. Mol Cancer. 2010 Mar 4;9:49.  [Content Brief]

      [2]. Lautz TB, et al. The effect of vorinostat on the development of resistance to NSC 123127 in neuroblastoma. PLoS One. 2012;7(7):e40816.  [Content Brief]

      [3]. Richon VM, et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.  [Content Brief]

      [4]. Xu WS, et al. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene. 2007 Aug 13;26(37):5541-52.  [Content Brief]

      [5]. Pérez-Cañamás A, et al. Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease. Mol Psychiatry. 2017 May;22(5):711-723.  [Content Brief]

      [6]. Wang J, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017 Dec 20;8(1):2207.  [Content Brief]

      [7]. Banerjee NS, et al. Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11138-E11147.  [Content Brief]

    Zellassay
    [1]

    Cell lysates are prepared by using RIPA buffer (25 mM Tris-HCl pH 7.6, 150 mM NaCl, 1% NP-40, 1% sodium deoxycholate, 0.1% SDS), and the protein concentration is determined by Bio-Rad DC Protein Assay. Protein lysates are separated by SDS-PAGE and transferred to nitrocellulose membrane. Following antibodies and dilutions are used: rabbit anti HDAC1 (1 μg/mL); rabbit anti HDAC2 (1 μg/mL); rabbit anti HDAC3 (9 μg/mL); rabbit anti HDAC7 (3 μg/mL); mouse anti p21WAF1 (0.5 μg/mL). As secondary antibodies, the rabbit anti-mouse and swine anti-rabbit HRP-coupled antibodies at a final concentration of 1 μg/mL. An overnight incubation at 4°C is used for all primary antibodies, followed by washing and 2-hours incubation at RT with secondary antibodies. Specific protein bands are visualized by enhanced chemiluminescence assay. To demonstrate equal loading of protein samples all western blots are probed for β-tubulin.

    MCE hat die Genauigkeit dieser Methoden nicht unabhängig bestätigt. Sie dienen nur als Referenz.
    Tierverwaltung
    [1]

    Twelve weeks old male mice (n=14) are anesthetized with Isofluran and 5×106 MES-SA cells are injected subcutaneously into the right flank of the animal. Mice from a control group receives placebo containing 300 μL of empty HOP-β-CD (2-hydroxypropyl-β-cyclodextrin) vesicles. Another group of mice receives vorinostat dissolved in HOP-β-CD at a concentration of 50 mg/kg/day. Both, empty vesicles and vorinostat are administered intraperitoneally, starting on the day 4 after the injection of MES-SA tumor cells. Mice body weight and tumor size (w2 × l × 0.52; measured by caliper) are estimated twice a week. All mice are treated for 21 days and afterwards sacrificed by cervical dislocation. Each tumor is isolated as a whole and different tumor parameters are determined. Finally, tumor slices are cryo preserved and formalin fixed (4%) for further analyses.

    MCE hat die Genauigkeit dieser Methoden nicht unabhängig bestätigt. Sie dienen nur als Referenz.
    Verweise

    • [1]. Hrzenjak A et al. Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. Mol Cancer. 2010 Mar 4;9:49.  [Content Brief]

      [2]. Lautz TB, et al. The effect of vorinostat on the development of resistance to NSC 123127 in neuroblastoma. PLoS One. 2012;7(7):e40816.  [Content Brief]

      [3]. Richon VM, et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.  [Content Brief]

      [4]. Xu WS, et al. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene. 2007 Aug 13;26(37):5541-52.  [Content Brief]

      [5]. Pérez-Cañamás A, et al. Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease. Mol Psychiatry. 2017 May;22(5):711-723.  [Content Brief]

      [6]. Wang J, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017 Dec 20;8(1):2207.  [Content Brief]

      [7]. Banerjee NS, et al. Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11138-E11147.  [Content Brief]

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 3.7833 mL 18.9165 mL 37.8329 mL 94.5823 mL
    5 mM 0.7567 mL 3.7833 mL 7.5666 mL 18.9165 mL
    10 mM 0.3783 mL 1.8916 mL 3.7833 mL 9.4582 mL
    15 mM 0.2522 mL 1.2611 mL 2.5222 mL 6.3055 mL
    20 mM 0.1892 mL 0.9458 mL 1.8916 mL 4.7291 mL
    25 mM 0.1513 mL 0.7567 mL 1.5133 mL 3.7833 mL
    30 mM 0.1261 mL 0.6305 mL 1.2611 mL 3.1527 mL
    40 mM 0.0946 mL 0.4729 mL 0.9458 mL 2.3646 mL
    50 mM 0.0757 mL 0.3783 mL 0.7567 mL 1.8916 mL
    60 mM 0.0631 mL 0.3153 mL 0.6305 mL 1.5764 mL
    80 mM 0.0473 mL 0.2365 mL 0.4729 mL 1.1823 mL
    100 mM 0.0378 mL 0.1892 mL 0.3783 mL 0.9458 mL
    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    Vorinostat Related Classifications

    Help & FAQs

    Keywords:

    Vorinostat149647-78-9SAHA Suberoylanilide hydroxamic acidHDACAutophagyMitophagyFilovirusApoptosisHPVHistone deacetylasesMitochondrial AutophagyHuman papillomavirusInhibitorinhibitorinhibit

    Sie könnten auch an folgenden Produkten interessiert sein:



    Katalog-Nummer
    Beschreibung
    Cond.
    Preis zzgl. MwSt.
    6160-05
    Rabbit Anti-Goat IgG(H+L)-HRP
     1.0mL