TTL Human Gene Knockout Kit (CRISPR)
Katalog-Nummer KN207805BN
Size : 1kit
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TTL Human Gene Knockout Kit (CRISPR)
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | TTL |
| Locus ID | 150465 |
| Components | KN207805G1, TTL gRNA vector 1 in pCas-Guide CRISPR vector KN207805G2, TTL gRNA vector 2 in pCas-Guide CRISPR vector KN207805BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_153712 |
| UniProt ID | Q8NG68 |
| Synonyms | MGC46235 |
| Summary | TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008] |
| Shipping | Ambient |
More linear donor DNA can be ordered separately
| Cat# | KN207805BND |
| Description | 10 ug linear donor DNA for KN207805BN kit |
| /€515 |
If you want to order 50ug, please order quantity of 5 for KN207805BND
Other selection marker is available for donor DNA.
Please contact tech@biotrend.com for a custom quote.
| Product Manuals |
| FAQs |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| GA115753 | TTL CRISPRa kit - CRISPR gene activation of human tubulin tyrosine ligase | 1 kit | | |
| KN207805 | TTL - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN207805LP | TTL - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN207805RB | TTL - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN407805 | TTL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.