Size : 5 ug
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Glycosylation of MCP-1/CCL2 has been shown to substantially improve its half-life when incubated at 37 degrees C. Symansis' purified MCP-1/CCL2hcx consists of up to 55% carbohydrate by weight.
Monocyte chemotactic protein-1 (MCP-1) is a member of the C-C chemokine family. MCP-1 exhibits chemotactic activity for a range of lymphocytes, but not neutrophils or eosinophils. It also exhibits chemotactic activity for neural stem cells. MCP-1 is expressed by a range of cells in response to the cytokines IL-1, TNF-a, IFN-g, as well as bacterial or viral products and mitogens.
1. Rose CE Jr., et al. (2003) Microcirculation 10: 273-88.
2. Ruggiero P, et al. (2003) Eur Cytokine Netw. 14: 91-6.
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