Recombinant Chicken EGF

Katalog-Nummer RP1409C-005

Size : 5ug

Marke : Kingfisher Biotech

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EGF (Epidermal Growth Factor) is best known for having the ability to stimulate cell growth and proliferation. There are many EGF responses and they are regulated by seven ligands: EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF-like growth factor (HBEGF), betacellulin (BTC), amphiregulin (AREG), epiregulin (EREG), and epigen (EPGN) and four ErbB (HER) family receptor tyrosine kinases: EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. EGF family members are important for development and promoting mitogenesis and differentiation of mesenchymal and epithelial cells. EGF acts as a mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. EGF plays a significant role in epithelial development, angiogenesis, regulation of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture. EGF dysregulation is also associated with the growth and progression of many cancers.

Low concentrations of EGF distinguish high-producing and repeat breeder cows from normal cows. The dairy cows having a normal EGF expression profile show a higher pregnancy rate than cows with aberrant EGF expression profiles. Evidence links EGF to embryogenesis and/or implantation in mammalian species by influencing growth-promoting activities on the conceptus and endometrium. EGF regulation is especially crucial in breeding pigs because they have a non-invasive placentation and a prolonged implantation period.

Alternate Names - EGF, HOMG4, URG, epidermal growth factor, Epidermal growth factor​

Amino Acid Homology Across Species
Gallus gallus (chicken) EGF – 100%
Coturnix japonica (Japanese quail) EGF – 96%
Meleagris gallopavo (turkey) EGF – 96%
Anas platyrhynchos (mallard) EGF – 96%
Anser cygnoides domesticus (domestic goose) EGF – 96%
Nipponia nippon (crested ibis) EGF – 96%
Phalacrocorax carbo (great cormorant) EGF – 96%

Catalog No.:
RP1409C-005
Quantity:
5 ug
Source:
The Chicken EGF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Chicken EGF recombinant protein has a predicted molecular weight of 6.2 kDa.
Protein Sequence:
GDSIGCPPAY DSYCLHGGVC NYVSDLQDYA CNCVTGYVGE RCQFSDLEWW EQQHA (55)
Alias:
Epidermal Growth Factor
Country of Origin:
USA
Applications:
The Chicken EGF endotoxin-free recombinant protein can be used in cell culture, as an EGF ELISA Standard, and as a Western Blot Control.


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Katalog-Nummer
Beschreibung
Cond.
Preis zzgl. MwSt.
RP1395C-005
 5ug