Rat S100A4 (S100 Calcium Binding Protein A4) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	S100a4
Gene ID:	24615
Uniprot ID:	S10A4_RAT
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Modulates also the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors.
Protein Name	Protein S100-A4 Metastasin Nerve Growth Factor-Induced Protein 42a P9k Placental Calcium-Binding Protein S100 Calcium-Binding Protein A4
Database Links
Cellular Localisation	Secreted Nucleus Cytoplasm
Alternative ELISA Names	Protein S100-A4 ELISA kit Metastasin ELISA kit Nerve Growth Factor-Induced Protein 42a ELISA kit P9k ELISA kit Placental Calcium-Binding Protein ELISA kit S100 Calcium-Binding Protein A4 ELISA kit S100a4 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance