These rat liver microsomes are prepared from Sprague Dawley rats and are suitable as controls in Western applications. Each vial contains enough material for more than 20 Westerns. Oxford Biomedical Research offers the following control preparations:

PC10

Male Rat Liver Microsomes

PC11

Female Rat Liver Microsomes

PC12

Clofibrate Induced Rat Liver (RL) Microsomes- exhibits high levels of CYP 4A (1)

PC16

Pyridine Induced RL Microsomes- exhibits high levels of CYP 2E1

PC18

Dexamethasone Induced RL Microsomes- exhibits high levels of CYP 3A.

PC21

3-Methylcholanthrene Induced RL Microsomes- exhibits high levels of CYP 1A1 and 1A2.

References

1. Zangar, et al., Arch. Biochem. Biophys. 337:217-224, 1997.
2. Kim, Putt, Reddy, Hollenberg, and Novak, J Pharm & Exp Therap 267: 927-936, 1993.
3. Kim, Reddy, and Novak, Drug Metab & Dispos 23:818-824, 1995.