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Anti-Cytokeratin/Keratin 17 Polyclonal Antibody
Category: Antibodies
Catalog
03-GP-CK17
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More Information
Product Name
Anti-Cytokeratin/Keratin 17 Polyclonal Antibody
Description
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Synonyms
PC, K17, PC2, PCHC1
Clonality
Polyclonal
Immunogen
Recombinant human Keratin 17
Specificity
Acidic human keratin K17 (Mr 46,000); formerly also designated cytokeratin 17. In the epidermis suprabasal staining is found only in cornifying regions and in the outer root sheath of hair follicles.
Reactivity
Human
Applications
IHC, WB
Form
Stabilized Serum
Storage
2-8C
References
Demirkesen, C. et al. (1995) J. Cutan. Pathol. 22: 518-535Moll, R. et al. (1995) In: Aktuelle Aspekte der Tumorimmunologie in der Gynaekologie. W. Zuckschwerdt VerlagJennemann R (2007) J Biol Chem 282: 3083-3094
Background
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Supplier
ARP
View product citations for antibody 03-GP-CK17 on CiteAb