Dimethyl sulfoxide [67-68-5]
Katalog-Nummer T0341-100mL
Size : 100mL
Marke : TargetMol
Dimethyl sulfoxide
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Dimethyl sulfoxide
Catalog No. T0341Cas No. 67-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
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100 mL | |
200 mL | |
500 mL |
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
Description | Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity. |
In vitro | METHODS: Human colorectal cancer cells HCT-116 and SW-480 were treated with Dimethyl sulfoxide (0.1%-1.5%) for 24 h, and cell viability was measured by MTT. RESULTS: Dimethyl sulfoxide showed a dose-dependent effect on cell proliferation. Cells treated with 1.5% Dimethyl sulfoxide showed about 10% reduction in cell growth. [1] |
In vivo | METHODS: To detect toxicity, Dimethyl sulfoxide (10%-100%) was administered to Swiss mice by single intraperitoneal injection for five days. RESULTS: The LD50 increased with decreasing concentration and the LD50 values for 10%, 25%, 50%, 75%, and 100% Dimethyl sulfoxide were >10.1, 15.4, 13.3, 11.9, and 10.9 g/kg, respectively. [2] |
Alias | Methyl Sulfoxide, DMSO |
Molecular Weight | 78.13 |
Formula | C2H6OS |
Cas No. | 67-68-5 |
Storage | store at RT |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg, each
animal weighs 20 g, and the dosage volume is 100 μL. A total of
10 animals were administered, and the formula you used is 5%
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSO
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSO
main solution, add 300 μLPEG300
mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2O
mix well and clarify.
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
solventbacteriostaticBacterialInhibitorinhibitanti-freezinganti-inflammatoryaproticDimethyl sulfoxide