CDK1 Mouse Monoclonal Antibody [Clone ID: POH-1]
Specifications
Product Data | |
Clone Name | POH-1 |
Applications | IF, IHC, IP, WB |
Recommended Dilution | Western Blot: 1-2 µg/ml. Immunoprecipitation. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Positive Control: Thymus. |
Reactivities | Human, Bovine |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Bacterially expressed full-length Human Cdk1 protein. |
Specificity | The antibody POH-1 specifically detects Cdk1 (p34Cdc2). Staining of Cdk1 reflects the proliferating potential of respective tissue. Negative Species: Mouse, Rat, Xenopus and Drosophila. |
Formulation | PBS, pH~7.4 State: Purified State: Liquid purified IgG fraction Preservative: 15 mM Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | cyclin-dependent kinase 1 |
Database Link | |
Background | The p34cdc2 is a 34 kDa phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. Expression of p34cdc2 reflects the proliferating potential of positively staining tissue. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. It is a 34kD catalytic subunit of maturation promoting factor (MPF) and complexes with both cyclin A and cyclin B in mammalian cells. |
Synonyms | CDK1, CDC2, CDC28A, CDKN1, P34CDC2, p34 protein kinase |
Reference Data |
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