CD8A Mouse Monoclonal Antibody [Clone ID: vpg9]
Katalog-Nummer SM424R
Size : 100Tests
Product Data | |
Clone Name | vpg9 |
---|---|
Application | FC |
Application | Flow Cytometry. |
Reactivity | Feline |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Feline thymocytes. Spleen cells from immunised BALB/c were fused with cells of the NSO mouse myeloma cell line |
Specificity | This antibody recognises the homologue of human CD8. Clone vpg 9 specifically recognises an epitope associated with the alpha/beta complex of the CD8 heterodimer. |
Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: PE State: Lyophilized purified IgG Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1 ml distilled water |
Conjugation | PE |
Storage | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
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