CD226 Mouse Monoclonal Antibody [Clone ID: DX11]
Katalog-Nummer SM2023LE
Size : 500ug
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| Product Data | |
| Clone Name | DX11 |
|---|---|
| Application | FC, FN, IP |
| Application | Flow Cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 1 x 10e6 cells in 100µl. Immunoprecipitation. Functional Assays. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line. |
| Specificity | This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells |
| Buffer | PBS, pH7.4 State: Low Endotoxin State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | CD226 molecule |
| Database Link | |
| Background | CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. |
| Synonyms | DNAX accessory molecule 1, DNAM-1 |
| Note | Endotoxin Level: less than 0.01 EU/µg |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.